9 items (Saprospira grandis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	adk	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (192 aa)
	udk	COG0572 Uridine kinase. (209 aa)
	pyrH	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa)
	SGRA_2628	COG1428 Deoxynucleoside kinases. (219 aa)
	ndk	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
	SGRA_3733	COG1428 Deoxynucleoside kinases. (210 aa)
	tdk	COG1435 Thymidine kinase. (184 aa)
	cmk	COG0283 Cytidylate kinase. (237 aa)
	gmk	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (206 aa)

Your Current Organism:

Saprospira grandis

NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SGRA_2628	gmk	SGRA_2628	SGRA_3886	COG1428 Deoxynucleoside kinases.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.917
SGRA_2628	tdk	SGRA_2628	SGRA_3788	COG1428 Deoxynucleoside kinases.	COG1435 Thymidine kinase.	0.501
SGRA_3733	adk	SGRA_3733	SGRA_0637	COG1428 Deoxynucleoside kinases.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.913
SGRA_3733	cmk	SGRA_3733	SGRA_3800	COG1428 Deoxynucleoside kinases.	COG0283 Cytidylate kinase.	0.910
SGRA_3733	tdk	SGRA_3733	SGRA_3788	COG1428 Deoxynucleoside kinases.	COG1435 Thymidine kinase.	0.562
adk	SGRA_3733	SGRA_0637	SGRA_3733	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	COG1428 Deoxynucleoside kinases.	0.913
adk	gmk	SGRA_0637	SGRA_3886	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.720
adk	ndk	SGRA_0637	SGRA_3714	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.938
adk	pyrH	SGRA_0637	SGRA_1595	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.496
cmk	SGRA_3733	SGRA_3800	SGRA_3733	COG0283 Cytidylate kinase.	COG1428 Deoxynucleoside kinases.	0.910
cmk	gmk	SGRA_3800	SGRA_3886	COG0283 Cytidylate kinase.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.484
cmk	ndk	SGRA_3800	SGRA_3714	COG0283 Cytidylate kinase.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.928
cmk	pyrH	SGRA_3800	SGRA_1595	COG0283 Cytidylate kinase.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.414
cmk	udk	SGRA_3800	SGRA_1088	COG0283 Cytidylate kinase.	COG0572 Uridine kinase.	0.922
gmk	SGRA_2628	SGRA_3886	SGRA_2628	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	COG1428 Deoxynucleoside kinases.	0.917
gmk	adk	SGRA_3886	SGRA_0637	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.720
gmk	cmk	SGRA_3886	SGRA_3800	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	COG0283 Cytidylate kinase.	0.484
gmk	ndk	SGRA_3886	SGRA_3714	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.925
gmk	pyrH	SGRA_3886	SGRA_1595	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.733
gmk	udk	SGRA_3886	SGRA_1088	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	COG0572 Uridine kinase.	0.400