STRINGSTRING
hemH hemH SGRA_0832 SGRA_0832 hemN hemN SGRA_1114 SGRA_1114 SGRA_1121 SGRA_1121 SGRA_1122 SGRA_1122 SGRA_1226 SGRA_1226 SGRA_1227 SGRA_1227 SGRA_1372 SGRA_1372 SGRA_1373 SGRA_1373 SGRA_1493 SGRA_1493 cyoE cyoE hemD hemD SGRA_2015 SGRA_2015 SGRA_2036 SGRA_2036 hemA hemA hemC hemC SGRA_2578 SGRA_2578 SGRA_3027 SGRA_3027 hemE hemE hemL hemL SGRA_4016 SGRA_4016 hemF hemF hemB hemB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (340 aa)
SGRA_0832COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain. (383 aa)
hemNOxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (349 aa)
SGRA_1114Cobalamin synthesis protein CobW; COG0523 Putative GTPases (G3E family). (332 aa)
SGRA_1121Hypothetical protein. (187 aa)
SGRA_1122Hypothetical protein. (249 aa)
SGRA_1226Von Willebrand factor type A; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. (333 aa)
SGRA_1227Von Willebrand factor type A; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. (336 aa)
SGRA_1372Cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (185 aa)
SGRA_1373COG1981 Predicted membrane protein. (188 aa)
SGRA_1493TPR repeat-containing protein; COG0457 FOG: TPR repeat. (563 aa)
cyoEProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (277 aa)
hemDuroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (262 aa)
SGRA_2015Porphobilinogen deaminase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (221 aa)
SGRA_2036Cytochrome oxidase assembly; COG1612 Uncharacterized protein required for cytochrome oxidase assembly. (383 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (466 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (298 aa)
SGRA_2578Von Willebrand factor type A; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. (550 aa)
SGRA_3027Regulatory protein (nitrile hydratase activator like); COG0523 Putative GTPases (G3E family). (401 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (342 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; COG0001 Glutamate-1-semialdehyde aminotransferase. (428 aa)
SGRA_4016Hypothetical protein. (686 aa)
hemFCOG0408 Coproporphyrinogen III oxidase. (308 aa)
hemBCOG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (333 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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