STRINGSTRING
SGRA_4226 SGRA_4226 SGRA_1189 SGRA_1189 mtnN mtnN ampC-2 ampC-2 SGRA_1664 SGRA_1664 deoC deoC SGRA_1965 SGRA_1965 SGRA_2068 SGRA_2068 SGRA_2329 SGRA_2329 SGRA_2475 SGRA_2475 pnp pnp rnhB rnhB rny rny cdd cdd SGRA_2947 SGRA_2947 surE surE pncA pncA SGRA_3396 SGRA_3396 SGRA_3474 SGRA_3474 amn amn SGRA_3648 SGRA_3648 SGRA_3736 SGRA_3736 xseA xseA mazG mazG dut dut SGRA_3885 SGRA_3885 SGRA_3989 SGRA_3989 SGRA_4026 SGRA_4026 SGRA_4209 SGRA_4209 SGRA_4225 SGRA_4225 SGRA_0085 SGRA_0085 kynU kynU SGRA_0949 SGRA_0949
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGRA_4226Metallophosphoesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (319 aa)
SGRA_1189Amidohydrolase 3; COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold. (564 aa)
mtnNPurine or other phosphorylase family 1; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (227 aa)
ampC-2COG2367 Beta-lactamase class A. (350 aa)
SGRA_1664Hypothetical protein; COG3386 Gluconolactonase. (265 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa)
SGRA_1965Beta-lactamase domain protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; Belongs to the UPF0173 family. (232 aa)
SGRA_2068Metal dependent phosphohydrolase; COG1078 HD superfamily phosphohydrolases. (406 aa)
SGRA_2329Putative deoxyribonucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (195 aa)
SGRA_2475MazG nucleotide pyrophosphohydrolase; COG1694 Predicted pyrophosphatase. (113 aa)
pnpPolynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (747 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (205 aa)
rnyPhosphodiesterase; Endoribonuclease that initiates mRNA decay. (545 aa)
cddCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (161 aa)
SGRA_2947Extracellular nuclease. (679 aa)
surE5'(3')-nucleotidase/polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (256 aa)
pncANicotinamidase; COG1335 Amidases related to nicotinamidase. (207 aa)
SGRA_33965 nucleotidase deoxy cytosolic type C; COG4502 Uncharacterized protein conserved in bacteria. (149 aa)
SGRA_3474N-formylkynurenine (aryl-) formamidase. (254 aa)
amnAMP nucleosidase; COG0775 Nucleoside phosphorylase. (257 aa)
SGRA_3648Hypothetical protein; COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase. (271 aa)
SGRA_3736Hypothetical protein; COG0210 Superfamily I DNA and RNA helicases. (1481 aa)
xseACOG1570 Exonuclease VII, large subunit; Belongs to the XseA family. (399 aa)
mazGNucleoside triphosphate pyrophosphohydrolase; COG1694 Predicted pyrophosphatase. (254 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa)
SGRA_3885Hypothetical protein; COG1561 Uncharacterized stress-induced protein. (287 aa)
SGRA_3989phytanoyl-CoA dioxygenase. (315 aa)
SGRA_4026Hypothetical protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold. (262 aa)
SGRA_4209Cyclase family protein; COG1878 Predicted metal-dependent hydrolase. (256 aa)
SGRA_42255'-Nucleotidase domain protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. (252 aa)
SGRA_0085Lipoprotein. (602 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (425 aa)
SGRA_0949COG1722 Exonuclease VII small subunit. (65 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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