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| | SGRA_4226 | Metallophosphoesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (319 aa) |
| | SGRA_0015 | Calcium-binding EF-hand-containing protein; COG5126 Ca2+-binding protein (EF-Hand superfamily). (150 aa) |
| | trkH | Trk system potassium uptake protein; COG0168 Trk-type K+ transport systems, membrane components. (500 aa) |
| | SGRA_0034 | Putative metallopeptidase, M16 family protein. (336 aa) |
| | SGRA_0042 | Hypothetical protein. (479 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa) |
| | SGRA_0114 | COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes. (348 aa) |
| | SGRA_0122 | COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (435 aa) |
| | SGRA_0133 | Cytochrome c family protein. (203 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (537 aa) |
| | uppS | Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (259 aa) |
| | SGRA_0207 | Tetratricopeptide repeat domain protein; COG0457 FOG: TPR repeat. (285 aa) |
| | SGRA_0210 | Tetratricopeptide TPR_2; COG0457 FOG: TPR repeat. (282 aa) |
| | kdsC | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). (174 aa) |
| | rlmN | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (348 aa) |
| | sodA | Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (256 aa) |
| | SGRA_0275 | COG1343 Uncharacterized protein predicted to be involved in DNA repair. (98 aa) |
| | cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (321 aa) |
| | SGRA_0280 | COG2010 Cytochrome c, mono- and diheme variants. (121 aa) |
| | nfi | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (229 aa) |
| | SGRA_0329 | 2OG-Fe(II) oxygenase; COG3751 Predicted proline hydroxylase. (195 aa) |
| | mrp | ATP-binding protein, Mrp/Nbp35 family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (364 aa) |
| | SGRA_0369 | Lvivd repeat-containing protein. (430 aa) |
| | sodA-2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (203 aa) |
| | SGRA_0379 | Hypothetical protein. (150 aa) |
| | SGRA_0387 | Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. (119 aa) |
| | SGRA_0509 | 2OG-Fe(II) oxygenase; COG3491 Isopenicillin N synthase and related dioxygenases; Belongs to the iron/ascorbate-dependent oxidoreductase family. (318 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (340 aa) |
| | map | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (267 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (537 aa) |
| | SGRA_0555 | Hypothetical protein; COG0730 Predicted permeases. (252 aa) |
| | gloA | methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. (133 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (304 aa) |
| | SGRA_0599 | COG0694 Thioredoxin-like proteins and domains. (82 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | obgE | GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (335 aa) |
| | rimO | SSU ribosomal protein s12p methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (441 aa) |
| | prpE | prpE protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (627 aa) |
| | pilC | COG1459 Type II secretory pathway, component PulF. (375 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (422 aa) |
| | SGRA_0702 | 23S rRNA (uracil-5-)-methyltransferase RumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (501 aa) |
| | add | COG1816 Adenosine deaminase. (431 aa) |
| | icd | COG0473 Isocitrate/isopropylmalate dehydrogenase. (481 aa) |
| | SGRA_0716 | COG1858 Cytochrome c peroxidase. (327 aa) |
| | SGRA_0730 | Hypothetical protein. (169 aa) |
| | SGRA_0746 | Putative zinc-type alcohol dehydrogenase-like protein; COG1064 Zn-dependent alcohol dehydrogenases. (335 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (839 aa) |
| | SGRA_0771 | Hypothetical protein. (617 aa) |
| | SGRA_0786 | Hypothetical protein; COG4570 Holliday junction resolvase. (186 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (227 aa) |
| | SGRA_0798 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). (286 aa) |
| | lpxH | Metallophosphoesterase; COG2908 Uncharacterized protein conserved in bacteria. (265 aa) |
| | coaX | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (247 aa) |
| | SGRA_0842 | Amidohydrolase; COG1228 Imidazolonepropionase and related amidohydrolases. (430 aa) |
| | SGRA_0843 | Amidohydrolase; COG1228 Imidazolonepropionase and related amidohydrolases. (1008 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (876 aa) |
| | ribBA | Gtp cyclohydrolase ii; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (415 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (491 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (417 aa) |
| | cysS | COG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (556 aa) |
| | engB | GTP-binding protein HSR1-related protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (202 aa) |
| | SGRA_0933 | Phosphopantetheinyl transferase-like protein; COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (210 aa) |
| | ppnK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (295 aa) |
| | katE | COG0753 Catalase; Belongs to the catalase family. (504 aa) |
| | speA | Orn/DAP/Arg decarboxylase 2; COG1166 Arginine decarboxylase (spermidine biosynthesis). (465 aa) |
| | SGRA_1005 | Aminopeptidase; COG1363 Cellulase M and related proteins. (354 aa) |
| | hemN | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (349 aa) |
| | SGRA_1023 | RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (554 aa) |
| | SGRA_1024 | Zinc finger SWIM domain protein. (534 aa) |
| | SGRA_1027 | COG1864 DNA/RNA endonuclease G, NUC1. (410 aa) |
| | fbp | COG0158 Fructose-1,6-bisphosphatase. (327 aa) |
| | SGRA_1051 | 4Fe-4S ferredoxin, iron-sulfur binding protein; COG1145 Ferredoxin. (118 aa) |
| | crtR | Beta-carotene hydroxylase. (154 aa) |
| | queE | Radical SAM family protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (255 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (185 aa) |
| | SGRA_1090 | Radical SAM domain-containing protein; COG0641 Arylsulfatase regulator (Fe-S oxidoreductase). (404 aa) |
| | phhA | COG3186 Phenylalanine-4-hydroxylase. (245 aa) |
| | SGRA_1092 | Hypothetical protein. (334 aa) |
| | SGRA_1094 | Hypothetical protein; COG0247 Fe-S oxidoreductase. (268 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (902 aa) |
| | astE | Succinylglutamate desuccinylase/aspartoacylase family protein; COG2988 Succinylglutamate desuccinylase. (333 aa) |
| | SGRA_1113 | FeS assembly protein IscX; COG2975 Uncharacterized protein conserved in bacteria. (79 aa) |
| | recO | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (238 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (417 aa) |
| | SGRA_1151 | Nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (399 aa) |
| | hppD | COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins. (364 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (392 aa) |
| | SGRA_1211 | Peptidase M1 membrane alanine aminopeptidase; COG0308 Aminopeptidase N. (668 aa) |
| | SGRA_1236 | COG2120 Uncharacterized proteins, LmbE homologs. (238 aa) |
| | SGRA_1245 | Alcohol dehydrogenase zinc-binding domain protein; COG1064 Zn-dependent alcohol dehydrogenases. (350 aa) |
| | SGRA_1252 | Glycosyl transferase group 1; COG0535 Predicted Fe-S oxidoreductases. (341 aa) |
| | SGRA_1281 | Hypothetical protein. (611 aa) |
| | ftsH | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (675 aa) |
| | mqnC | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (380 aa) |
| | SGRA_1349 | Hypothetical protein; COG0247 Fe-S oxidoreductase. (455 aa) |
| | SGRA_1373 | COG1981 Predicted membrane protein. (188 aa) |
| | SGRA_1374 | Hypothetical protein. (137 aa) |
| | cynT | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (196 aa) |
| | speB | Arginase/agmatinase/formiminoglutamase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. (342 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (623 aa) |
| | thiE | Thiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase. (218 aa) |
| | thiE-2 | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (218 aa) |
| | lysS | COG1190 Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family. (545 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1123 aa) |
| | coxB | Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (462 aa) |
| | SGRA_1511 | COG2010 Cytochrome c, mono- and diheme variants. (252 aa) |
| | SGRA_1512 | Hypothetical protein. (177 aa) |
| | SGRA_1514 | Putative iron-sulfur binding oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing. (1121 aa) |
| | SGRA_1515 | COG2857 Cytochrome c1. (486 aa) |
| | gcp | UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (396 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (320 aa) |
| | SGRA_1545 | Metallophosphoesterase; COG2908 Uncharacterized protein conserved in bacteria. (281 aa) |
| | lpxC | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (461 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (213 aa) |
| | thiH | COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (381 aa) |
| | SGRA_1653 | Membrane associated hydrolase. (851 aa) |
| | suhB | Inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (268 aa) |
| | cysQ | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (263 aa) |
| | sdaA-2 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (482 aa) |
| | SGRA_1736 | Peptidase M16 domain protein; COG0612 Predicted Zn-dependent peptidases. (425 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (683 aa) |
| | SGRA_1751 | Hypothetical protein. (256 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (335 aa) |
| | ubiD | UbiD family decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. (610 aa) |
| | SGRA_1806 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (713 aa) |
| | SGRA_1870 | Hypothetical protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. (138 aa) |
| | iscU | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa) |
| | SGRA_1884 | Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. (108 aa) |
| | icmF | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1119 aa) |
| | trmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (455 aa) |
| | SGRA_1941 | Phosphodiesterase, MJ0936 family protein; COG0622 Predicted phosphoesterase. (173 aa) |
| | SGRA_1957 | FeoA family protein. (120 aa) |
| | ruvC | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (177 aa) |
| | pfk | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa) |
| | SGRA_1980 | Putative Zn-dependent aminopeptidase; COG0308 Aminopeptidase N. (1009 aa) |
| | cydA | COG1271 Cytochrome bd-type quinol oxidase, subunit 1. (459 aa) |
| | ptpS | COG0720 6-pyruvoyl-tetrahydropterin synthase. (138 aa) |
| | SGRA_2021 | Mov34/MPN/PAD-1 family protein; COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily. (155 aa) |
| | mtnB | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (224 aa) |
| | SGRA_2033 | Putative Zn-dependent aminopeptidase; COG0308 Aminopeptidase N. (753 aa) |
| | SGRA_2036 | Cytochrome oxidase assembly; COG1612 Uncharacterized protein required for cytochrome oxidase assembly. (383 aa) |
| | SGRA_2042 | Peptidase m48 ste24p; COG4783 Putative Zn-dependent protease, contains TPR repeats. (265 aa) |
| | SGRA_2044 | Arginase. (349 aa) |
| | SGRA_2047 | Hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (365 aa) |
| | SGRA_2067 | Putative zinc protease; COG0612 Predicted Zn-dependent peptidases. (412 aa) |
| | pheS | COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (345 aa) |
| | ftnA | Ferritin 1; Iron-storage protein. (172 aa) |
| | rnhA | Putative ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family. (209 aa) |
| | uvrA | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (943 aa) |
| | queG | Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (309 aa) |
| | ybeY | Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (145 aa) |
| | mutY | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (402 aa) |
| | apbE | Thiamin biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. (327 aa) |
| | SGRA_2187 | COG0723 Rieske Fe-S protein. (137 aa) |
| | SGRA_2189 | COG1734 DnaK suppressor protein. (138 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (510 aa) |
| | radC | COG2003 DNA repair proteins; Belongs to the UPF0758 family. (242 aa) |
| | SGRA_2198 | COG0694 Thioredoxin-like proteins and domains. (207 aa) |
| | SGRA_2212 | Hypothetical protein. (195 aa) |
| | tadA | Cmp/dcmp deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa) |
| | SGRA_2247 | COG2120 Uncharacterized proteins, LmbE homologs. (237 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; COG1995 Pyridoxal phosphate biosynthesis protein; Belongs to the PdxA family. (517 aa) |
| | pqqL | Peptidase m16 domain protein; COG0612 Predicted Zn-dependent peptidases; Belongs to the peptidase M16 family. (985 aa) |
| | ppa | COG0221 Inorganic pyrophosphatase. (209 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1420 aa) |
| | SGRA_2318 | Galanin. (302 aa) |
| | SGRA_2325 | Hypothetical protein. (205 aa) |
| | SGRA_2329 | Putative deoxyribonucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (195 aa) |
| | SGRA_2361 | Beta-lactamase domain protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (216 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (342 aa) |
| | SGRA_2383 | Putative vitamin B12 receptor precursor; COG1629 Outer membrane receptor proteins, mostly Fe transport. (882 aa) |
| | hutI | COG1228 Imidazolonepropionase and related amidohydrolases. (418 aa) |
| | SGRA_2392 | COG3000 Sterol desaturase. (401 aa) |
| | cah | COG3338 Carbonic anhydrase. (281 aa) |
| | uvrA-2 | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (930 aa) |
| | SGRA_2430 | Peptidase, M16 family protein; COG0612 Predicted Zn-dependent peptidases; Belongs to the peptidase M16 family. (956 aa) |
| | hflX | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (403 aa) |
| | rfbA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (289 aa) |
| | miaB | (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (483 aa) |
| | mtnC | 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (226 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (252 aa) |
| | pyk | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa) |
| | pnp | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (747 aa) |
| | SGRA_2533 | COG0308 Aminopeptidase N. (548 aa) |
| | SGRA_2545 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (413 aa) |
| | rng | COG1530 Ribonucleases G and E. (520 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (205 aa) |
| | SGRA_2576 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (361 aa) |
| | SGRA_2611 | COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family. (538 aa) |
| | metH | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1225 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (456 aa) |
| | sprA | Gliding motility protein SprA. (2512 aa) |
| | SGRA_2706 | COG1858 Cytochrome c peroxidase. (400 aa) |
| | SGRA_2707 | Hypothetical protein. (259 aa) |
| | pcrB | Geranylgeranylglyceryl phosphate synthase-like protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). (236 aa) |
| | rsgA | GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (312 aa) |
| | SGRA_2736 | Hypothetical protein; COG0730 Predicted permeases. (247 aa) |
| | SGRA_2764 | Hypothetical protein. (373 aa) |
| | SGRA_2767 | Peptidase m1 membrane alanine aminopeptidase; COG0308 Aminopeptidase N. (630 aa) |
| | icd-2 | COG0538 Isocitrate dehydrogenases. (399 aa) |
| | copA | Heavy metal translocating p-type atpase; COG2217 Cation transport ATPase. (739 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (831 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (875 aa) |
| | pepN | Peptidase M1 membrane alanine aminopeptidase; COG0308 Aminopeptidase N. (874 aa) |
| | cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (161 aa) |
| | SGRA_2812 | Biotin/lipoyl attachment domain-containing protein; COG0511 Biotin carboxyl carrier protein. (160 aa) |
| | SGRA_2826 | Beta-lactamase domain protein; COG0491 Zn-dependent hydrolases, including glyoxylases. (297 aa) |
| | pepT | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (409 aa) |
| | SGRA_2850 | Hypothetical protein. (1172 aa) |
| | SGRA_2861 | COG0621 2-methylthioadenine synthetase. (448 aa) |
| | vanX | Peptidase m15d vanx d-ala-d-ala dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (258 aa) |
| | troR | Iron dependent repressor; COG1321 Mn-dependent transcriptional regulator. (223 aa) |
| | SGRA_2890 | COG2309 Leucyl aminopeptidase (aminopeptidase T). (365 aa) |
| | SGRA_2977 | Peptidase m48 ste24p; COG0501 Zn-dependent protease with chaperone function. (264 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (296 aa) |
| | SGRA_2997 | Galanin. (331 aa) |
| | SGRA_2998 | COG2010 Cytochrome c, mono- and diheme variants. (131 aa) |
| | SGRA_2999 | COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems. (211 aa) |
| | SGRA_3004 | Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. (344 aa) |
| | SGRA_3005 | Hypothetical protein. (176 aa) |
| | SGRA_3030 | Peptidase M50; COG0750 Predicted membrane-associated Zn-dependent proteases 1. (446 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) |
| | mtnD | Methionine salvage pathway protein E-2/E-2'; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (175 aa) |
| | nqrF | Na(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (442 aa) |
| | dps | COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family. (167 aa) |
| | rfbA-2 | Nucleotidyl transferase; COG1209 dTDP-glucose pyrophosphorylase. (331 aa) |
| | SGRA_3095 | Riboflavin biosynthesis protein ribd; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (348 aa) |
| | apbE-2 | Apbe family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. (338 aa) |
| | SGRA_3139 | Zinc finger swim domain-containing protein. (446 aa) |
| | SGRA_3143 | Copper-translocating P-type ATPase; COG2217 Cation transport ATPase. (71 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (202 aa) |
| | SGRA_3148 | Peptidase M42 family protein; COG1363 Cellulase M and related proteins. (360 aa) |
| | SGRA_3155 | COG1864 DNA/RNA endonuclease G, NUC1. (269 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (724 aa) |
| | SGRA_3188 | COG1858 Cytochrome c peroxidase. (459 aa) |
| | surE | 5'(3')-nucleotidase/polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (256 aa) |
| | manB | COG1109 Phosphomannomutase. (463 aa) |
| | SGRA_3271 | Hypothetical protein. (92 aa) |
| | clpX | Sigma 54 interacting domain protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (419 aa) |
| | gpm | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (510 aa) |
| | folE | COG0302 GTP cyclohydrolase I. (231 aa) |
| | ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (710 aa) |
| | pepF | Oligoendopeptidase, M3 family protein; COG1164 Oligoendopeptidase F. (562 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (695 aa) |
| | SGRA_3396 | 5 nucleotidase deoxy cytosolic type C; COG4502 Uncharacterized protein conserved in bacteria. (149 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (174 aa) |
| | acs | Acetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (633 aa) |
| | SGRA_3458 | COG1741 Pirin-related protein; Belongs to the pirin family. (287 aa) |
| | rpe | COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa) |
| | sms | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (464 aa) |
| | SGRA_3562 | Hypothetical protein. (790 aa) |
| | SGRA_3611 | Succinylglutamate desuccinylase/aspartoacylase; COG3608 Predicted deacylase. (319 aa) |
| | gshB | COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase). (322 aa) |
| | SGRA_3613 | Hypothetical protein. (481 aa) |
| | SGRA_3624 | Carboxypeptidase Taq; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. (499 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (378 aa) |
| | lemA | LemA family protein; COG0457 FOG: TPR repeat. (328 aa) |
| | acnA | Aconitate hydratase; COG1048 Aconitase A. (759 aa) |
| | SGRA_3668 | Galanin; COG0556 Helicase subunit of the DNA excision repair complex. (323 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (405 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
| | SGRA_3716 | Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (181 aa) |
| | mqnE | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (417 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (330 aa) |
| | hmgA | COG3508 Homogentisate 1,2-dioxygenase. (386 aa) |
| | SGRA_3772 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (497 aa) |
| | tdk | COG1435 Thymidine kinase. (184 aa) |
| | SGRA_3797 | Periplasmic binding protein; COG4558 ABC-type hemin transport system, periplasmic component. (304 aa) |
| | SGRA_3819 | Peptidase M1 membrane alanine aminopeptidase; COG0308 Aminopeptidase N. (675 aa) |
| | sfcA | Malate dehydrogenase; COG0281 Malic enzyme. (403 aa) |
| | SGRA_3832 | Hypothetical protein. (378 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa) |
| | SGRA_3842 | Nucleotidyl transferase; COG1209 dTDP-glucose pyrophosphorylase. (328 aa) |
| | katE-2 | COG0753 Catalase. (576 aa) |
| | apaG | Co2+/Mg2+ efflux protein ApaG; COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. (129 aa) |
| | bioA | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (432 aa) |
| | dps-2 | COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family. (158 aa) |
| | SGRA_3933 | 4'-phosphopantetheinyl transferase superfamily protein; COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); Belongs to the P-Pant transferase superfamily. (190 aa) |
| | SGRA_3976 | Hypothetical protein. (461 aa) |
| | SGRA_3989 | phytanoyl-CoA dioxygenase. (315 aa) |
| | rocF | Arginase/agmatinase/formiminoglutamase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. (326 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (672 aa) |
| | hemF | COG0408 Coproporphyrinogen III oxidase. (308 aa) |
| | SGRA_4095 | Hypothetical protein. (358 aa) |
| | manB-2 | COG1109 Phosphomannomutase. (467 aa) |
| | ptpS-2 | COG0720 6-pyruvoyl-tetrahydropterin synthase. (138 aa) |
| | hemB | COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (333 aa) |
| | SGRA_4151 | COG4206 Outer membrane cobalamin receptor protein. (676 aa) |
| | SGRA_4195 | COG1858 Cytochrome c peroxidase. (330 aa) |
| | SGRA_4209 | Cyclase family protein; COG1878 Predicted metal-dependent hydrolase. (256 aa) |
