STRINGSTRING
efp efp SGRA_2643 SGRA_2643 SGRA_2648 SGRA_2648 SGRA_2650 SGRA_2650 SGRA_2653 SGRA_2653 oxyR oxyR SGRA_2699 SGRA_2699 infC infC troR troR lrp lrp SGRA_2979 SGRA_2979 fur-2 fur-2 marC marC SGRA_3138 SGRA_3138 SGRA_3173 SGRA_3173 SGRA_3207 SGRA_3207 SGRA_3208 SGRA_3208 SGRA_3209 SGRA_3209 SGRA_3210 SGRA_3210 SGRA_3211 SGRA_3211 SGRA_3212 SGRA_3212 SGRA_3213 SGRA_3213 mcp mcp SGRA_3220 SGRA_3220 cheY cheY cheB cheB cheA cheA rpoN rpoN SGRA_3250 SGRA_3250 SGRA_3261 SGRA_3261 rpoE-10 rpoE-10 SGRA_3372 SGRA_3372 SGRA_3379 SGRA_3379 SGRA_3446 SGRA_3446 pilH pilH phoB1-2 phoB1-2 SGRA_3549 SGRA_3549 SGRA_3560 SGRA_3560 SGRA_3587 SGRA_3587 SGRA_3596 SGRA_3596 nusB nusB SGRA_3650 SGRA_3650 SGRA_3651 SGRA_3651 SGRA_3662 SGRA_3662 SGRA_3663 SGRA_3663 SGRA_3683 SGRA_3683 SGRA_3827 SGRA_3827 oxyR-2 oxyR-2 SGRA_3852 SGRA_3852 oxyR-3 oxyR-3 SGRA_3882 SGRA_3882 SGRA_3957 SGRA_3957 SGRA_4009 SGRA_4009 SGRA_4027 SGRA_4027 SGRA_4073 SGRA_4073 lpd-2 lpd-2 SGRA_4095 SGRA_4095 SGRA_4102 SGRA_4102 rpoE-11 rpoE-11 SGRA_4184 SGRA_4184 asnC asnC SGRA_1158 SGRA_1158 SGRA_1244 SGRA_1244 SGRA_1246 SGRA_1246 SGRA_1250 SGRA_1250 SGRA_1255 SGRA_1255 pleC1 pleC1 SGRA_1279 SGRA_1279 hupB hupB SGRA_1288 SGRA_1288 SGRA_1293 SGRA_1293 rsfS rsfS birA birA SGRA_1355 SGRA_1355 SGRA_1375 SGRA_1375 SGRA_1410 SGRA_1410 SGRA_1412 SGRA_1412 SGRA_1467 SGRA_1467 eIF-1 eIF-1 prfB prfB SGRA_1510 SGRA_1510 SGRA_1541 SGRA_1541 phoR-2 phoR-2 SGRA_1554 SGRA_1554 tsf tsf rpoE-5 rpoE-5 rpoE-6 rpoE-6 rpoS rpoS mfd mfd fnr fnr SGRA_1732 SGRA_1732 rpoE-7 rpoE-7 SGRA_1788 SGRA_1788 infA infA fusA fusA SGRA_1856 SGRA_1856 SGRA_1857 SGRA_1857 SGRA_1866 SGRA_1866 SGRA_1892 SGRA_1892 prfC prfC SGRA_1935 SGRA_1935 SGRA_1937 SGRA_1937 SGRA_2030 SGRA_2030 greA greA SGRA_2092 SGRA_2092 SGRA_2093 SGRA_2093 SGRA_2114 SGRA_2114 SGRA_2115 SGRA_2115 SGRA_2118 SGRA_2118 SGRA_2152 SGRA_2152 SGRA_2160 SGRA_2160 SGRA_2161 SGRA_2161 SGRA_2162 SGRA_2162 SGRA_2167 SGRA_2167 SGRA_2168 SGRA_2168 SGRA_2169 SGRA_2169 recX recX prfA prfA mdaB mdaB SGRA_0144 SGRA_0144 SGRA_0177 SGRA_0177 SGRA_0178 SGRA_0178 SGRA_0197 SGRA_0197 phoR phoR phoB1 phoB1 SGRA_0310 SGRA_0310 SGRA_0326 SGRA_0326 SGRA_0344 SGRA_0344 SGRA_0390 SGRA_0390 SGRA_0410 SGRA_0410 dacA dacA SGRA_0451 SGRA_0451 SGRA_0494 SGRA_0494 SGRA_0495 SGRA_0495 SGRA_0518 SGRA_0518 SGRA_0546 SGRA_0546 SGRA_0571 SGRA_0571 SGRA_0576 SGRA_0576 SGRA_0590 SGRA_0590 degS degS narL narL rpoE rpoE SGRA_0626 SGRA_0626 fur fur SGRA_0696 SGRA_0696 SGRA_0705 SGRA_0705 dnaA dnaA rpoE-2 rpoE-2 SGRA_0735 SGRA_0735 lpd lpd SGRA_0043 SGRA_0043 SGRA_0111 SGRA_0111 SGRA_0128 SGRA_0128 SGRA_0764 SGRA_0764 SGRA_0776 SGRA_0776 rpoD rpoD SGRA_0789 SGRA_0789 mraZ mraZ SGRA_0911 SGRA_0911 SGRA_1024 SGRA_1024 rpoE-3 rpoE-3 rpoE-4 rpoE-4 SGRA_1097 SGRA_1097 infB infB nusA nusA SGRA_1132 SGRA_1132 SGRA_1157 SGRA_1157 SGRA_2285 SGRA_2285 yhbH yhbH tufA tufA nusG nusG rplA rplA SGRA_2324 SGRA_2324 SGRA_2345 SGRA_2345 SGRA_2356 SGRA_2356 pal-3 pal-3 SGRA_2395 SGRA_2395 SGRA_2396 SGRA_2396 rpoE-8 rpoE-8 SGRA_2415 SGRA_2415 SGRA_2416 SGRA_2416 lepA lepA rpoE-9 rpoE-9 SGRA_2480 SGRA_2480 SGRA_2500 SGRA_2500 SGRA_2521 SGRA_2521 hupB-2 hupB-2 mutS2 mutS2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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efpElongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (188 aa)
SGRA_2643Hypothetical protein. (532 aa)
SGRA_2648COG0640 Predicted transcriptional regulators. (99 aa)
SGRA_2650Outer membrane assembly protein. (906 aa)
SGRA_2653Transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. (195 aa)
oxyRRedox-sensitive transcriptional activator OxyR; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (308 aa)
SGRA_2699COG1846 Transcriptional regulators. (216 aa)
infCCOG0290 Translation initiation factor 3 (IF-3); Belongs to the IF-3 family. (168 aa)
troRIron dependent repressor; COG1321 Mn-dependent transcriptional regulator. (223 aa)
lrpTranscriptional regulator, AsnC family protein; COG1522 Transcriptional regulators. (165 aa)
SGRA_2979Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins. (288 aa)
fur-2Fur family transcriptional regulator protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family. (139 aa)
marCMultiple antibiotic resistance (MarC)-related protein; COG2095 Multiple antibiotic transporter. (189 aa)
SGRA_3138Hypothetical protein. (509 aa)
SGRA_3173Regulatory protein tetr; COG1309 Transcriptional regulator. (202 aa)
SGRA_3207Transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (239 aa)
SGRA_3208Two component transcriptional regulator, LuxR family; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (175 aa)
SGRA_3209COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family. (99 aa)
SGRA_3210Anti-anti-sigma regulatory factor; COG0840 Methyl-accepting chemotaxis protein. (291 aa)
SGRA_3211COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (119 aa)
SGRA_3212Switch protein/serine-threonine kinase; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). (132 aa)
SGRA_3213Putative anti-sigma regulatory factor, serine/threonine protein kinase; COG0656 Aldo/keto reductases, related to diketogulonate reductase. (200 aa)
mcpMethyl-accepting chemotaxis protein; COG2202 FOG: PAS/PAC domain. (757 aa)
SGRA_3220CheW protein; COG0835 Chemotaxis signal transduction protein. (167 aa)
cheYChemotaxis response regulator (CheY); COG0784 FOG: CheY-like receiver. (127 aa)
cheBProtein-glutamate methylesterase, two-component response regulator, chemotaxis; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (349 aa)
cheACOG0643 Chemotaxis protein histidine kinase and related kinases. (551 aa)
rpoNCOG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog. (539 aa)
SGRA_3250Histidine kinase; COG0642 Signal transduction histidine kinase. (394 aa)
SGRA_3261Transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. (212 aa)
rpoE-10RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
SGRA_3372Transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (303 aa)
SGRA_3379COG0286 Type I restriction-modification system methyltransferase subunit. (911 aa)
SGRA_3446Histidine kinase; COG0591 Na+/proline symporter. (895 aa)
pilHTwo-component system response regulator; COG0784 FOG: CheY-like receiver. (122 aa)
phoB1-2Two component transcriptional regulator, winged helix family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (235 aa)
SGRA_3549Histidine kinase; COG0642 Signal transduction histidine kinase. (326 aa)
SGRA_3560COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (291 aa)
SGRA_3587Nad(p)h dehydrogenase (quinone); COG2249 Putative NADPH-quinone reductase (modulator of drug activity B). (193 aa)
SGRA_3596COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (211 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (311 aa)
SGRA_3650rsbR, positive regulator of sigma-B; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (286 aa)
SGRA_3651COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (289 aa)
SGRA_3662Hypothetical protein. (278 aa)
SGRA_3663Hypothetical protein. (270 aa)
SGRA_3683Hypothetical protein; COG0457 FOG: TPR repeat. (317 aa)
SGRA_3827Hypothetical protein. (120 aa)
oxyR-2Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (314 aa)
SGRA_3852Anti-anti-sigma regulatory factor; COG0840 Methyl-accepting chemotaxis protein. (288 aa)
oxyR-3Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (315 aa)
SGRA_3882COG1510 Predicted transcriptional regulators; Belongs to the GbsR family. (218 aa)
SGRA_3957Putative AraC family transcriptional regulator; COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain. (299 aa)
SGRA_4009SNARE associated Golgi protein-related protein. (202 aa)
SGRA_4027Putative transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (292 aa)
SGRA_4073Hypothetical protein; COG2378 Predicted transcriptional regulator. (338 aa)
lpd-2COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (470 aa)
SGRA_4095Hypothetical protein. (358 aa)
SGRA_4102rsbR, positive regulator of sigma-B; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (333 aa)
rpoE-11COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (201 aa)
SGRA_4184Two component regulator propeller domain protein; COG3292 Predicted periplasmic ligand-binding sensor domain. (357 aa)
asnCTranscriptional regulator, AsnC family protein; COG1522 Transcriptional regulators. (160 aa)
SGRA_1158Two component LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (231 aa)
SGRA_1244Hypothetical protein. (237 aa)
SGRA_1246AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (280 aa)
SGRA_1250Type 4 fimbriae expression regulatory protein PilR; COG3283 Transcriptional regulator of aromatic amino acids metabolism. (300 aa)
SGRA_1255Type 4 fimbriae expression regulatory protein PilR; COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain. (608 aa)
pleC1Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase. (678 aa)
SGRA_1279Hypothetical protein. (104 aa)
hupBDNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (108 aa)
SGRA_1288Transcriptional regulator, TetR family; COG1309 Transcriptional regulator. (228 aa)
SGRA_1293COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (290 aa)
rsfSIojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (130 aa)
birACOG0340 Biotin-(acetyl-CoA carboxylase) ligase. (272 aa)
SGRA_1355Smr protein/MutS2; COG1193 Mismatch repair ATPase (MutS family). (365 aa)
SGRA_1375RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
SGRA_1410Transcriptional regulator, ArsR family protein; COG0640 Predicted transcriptional regulators. (111 aa)
SGRA_1412Transcriptional regulator, ArsR family protein; COG0640 Predicted transcriptional regulators. (78 aa)
SGRA_1467Regulatory protein ArsR; COG0640 Predicted transcriptional regulators. (112 aa)
eIF-1COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins. (113 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (334 aa)
SGRA_1510Hypothetical protein. (497 aa)
SGRA_1541COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (241 aa)
phoR-2Histidine kinase; COG0642 Signal transduction histidine kinase. (500 aa)
SGRA_1554Transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (281 aa)
tsfElongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (278 aa)
rpoE-5COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (213 aa)
rpoE-6RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa)
rpoSPutative RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (290 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1122 aa)
fnrCRP family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. (223 aa)
SGRA_1732RNA polymerase, sigma-E factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)
rpoE-7RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
SGRA_1788Transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators. (294 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
fusAElongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (710 aa)
SGRA_1856Histidine kinase; COG0642 Signal transduction histidine kinase. (771 aa)
SGRA_1857Two component transcriptional regulator, LuxR family protein; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. (280 aa)
SGRA_1866Hypothetical protein. (189 aa)
SGRA_1892COG2207 AraC-type DNA-binding domain-containing proteins. (296 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (526 aa)
SGRA_1935LexA DNA-binding protein; COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen. (446 aa)
SGRA_1937COG0506 Proline dehydrogenase. (362 aa)
SGRA_2030Secreted protein. (180 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (160 aa)
SGRA_2092Histidine kinase; COG0642 Signal transduction histidine kinase. (728 aa)
SGRA_2093Two component transcriptional regulator, LuxR family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (289 aa)
SGRA_2114Transcriptional regulator, BadM/Rrf2 family protein; COG1959 Predicted transcriptional regulator. (145 aa)
SGRA_2115Two-component system response regulator; COG0784 FOG: CheY-like receiver. (520 aa)
SGRA_2118GumN family protein; COG3735 Uncharacterized protein conserved in bacteria. (314 aa)
SGRA_2152COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). (135 aa)
SGRA_2160COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (289 aa)
SGRA_2161COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (284 aa)
SGRA_2162COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (296 aa)
SGRA_2167COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (286 aa)
SGRA_2168COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (290 aa)
SGRA_2169COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (283 aa)
recXRegulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. (163 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa)
mdaBNAD(P)H dehydrogenase (quinone); COG2249 Putative NADPH-quinone reductase (modulator of drug activity B). (197 aa)
SGRA_0144Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (310 aa)
SGRA_0177Two component transcriptional regulator, LytTR family protein; COG3279 Response regulator of the LytR/AlgR family. (234 aa)
SGRA_0178Signal transduction histidine kinase, LytS; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain. (352 aa)
SGRA_0197RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
phoRHistidine kinase; COG0642 Signal transduction histidine kinase. (355 aa)
phoB1COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (237 aa)
SGRA_0310COG1733 Predicted transcriptional regulators. (113 aa)
SGRA_0326Histidine kinase; COG0642 Signal transduction histidine kinase. (1237 aa)
SGRA_0344Signal peptidase I. (114 aa)
SGRA_0390Response regulator receiver protein. (307 aa)
SGRA_0410Transcriptional regulator, Crp/Fnr family protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. (149 aa)
dacAHypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (256 aa)
SGRA_0451Hypothetical protein. (836 aa)
SGRA_0494Signal transduction histidine kinase, LytS; COG3275 Putative regulator of cell autolysis. (354 aa)
SGRA_0495Two component transcriptional regulator, LytTR family protein; COG3279 Response regulator of the LytR/AlgR family. (239 aa)
SGRA_0518Hypothetical protein. (105 aa)
SGRA_0546Putative transcriptional regulator, Crp/Fnr family; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. (190 aa)
SGRA_0571Anti-anti-sigma regulatory factor; COG0840 Methyl-accepting chemotaxis protein. (287 aa)
SGRA_0576COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (132 aa)
SGRA_0590Gaf sensor signal transduction histidine kinase; COG2203 FOG: GAF domain. (400 aa)
degSMulti-sensor signal transduction histidine kinase; COG2202 FOG: PAS/PAC domain. (1047 aa)
narLTwo component transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (219 aa)
rpoERNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (172 aa)
SGRA_0626COG5343 Uncharacterized protein conserved in bacteria. (281 aa)
furFerric-uptake regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family. (154 aa)
SGRA_0696COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family. (116 aa)
SGRA_0705Organic hydroperoxide resistance transcriptionalregulator; COG1846 Transcriptional regulators. (146 aa)
dnaAChromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (501 aa)
rpoE-2RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
SGRA_0735Penicillinase repressor; COG3682 Predicted transcriptional regulator. (108 aa)
lpdCOG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (472 aa)
SGRA_0043Type 4 fimbriae expression regulatory protein pilR; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (549 aa)
SGRA_0111Gaf sensor signal transduction histidine kinase; COG2203 FOG: GAF domain. (412 aa)
SGRA_0128COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (291 aa)
SGRA_0764Putative two component, sigma54 specific, transcriptional regulator, Fis family protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (421 aa)
SGRA_0776Hypothetical protein. (208 aa)
rpoDRNA polymerase, sigma 70 subunit, RpoD subfamily protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (290 aa)
SGRA_0789Hypothetical protein. (124 aa)
mraZMraZ protein; COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family. (153 aa)
SGRA_0911tetR family regulatory protein; COG1309 Transcriptional regulator. (211 aa)
SGRA_1024Zinc finger SWIM domain protein. (534 aa)
rpoE-3RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (152 aa)
rpoE-4RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
SGRA_1097GumN family protein; COG3735 Uncharacterized protein conserved in bacteria. (266 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (1002 aa)
nusATranscription elongation factor NusA; Participates in both transcription termination and antitermination. (438 aa)
SGRA_1132Two component, sigma54 specific, Fis family transcriptional regulator; COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain. (534 aa)
SGRA_1157Histidine kinase; COG4585 Signal transduction histidine kinase. (248 aa)
SGRA_2285RNA polymerase sigma factor, sigma-70 family protein; COG1191 DNA-directed RNA polymerase specialized sigma subunit. (199 aa)
yhbHRibosomal subunit interface protein; COG1544 Ribosome-associated protein Y (PSrp-1). (100 aa)
tufATranslation elongation factor 1a (ef-1a/ef-tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (395 aa)
nusGNusG antitermination factor; Participates in transcription elongation, termination and antitermination. (180 aa)
rplA50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (230 aa)
SGRA_2324Appr-1-p processing domain protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. (348 aa)
SGRA_2345COG3326 Predicted membrane protein. (93 aa)
SGRA_2356Two component regulator propeller domain protein; COG3292 Predicted periplasmic ligand-binding sensor domain. (770 aa)
pal-3OmpA/MotB domain-containing protein; COG0457 FOG: TPR repeat. (675 aa)
SGRA_2395ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (200 aa)
SGRA_2396anti-FecI sigma factor, FecR; COG3712 Fe2+-dicitrate sensor, membrane component. (339 aa)
rpoE-8RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
SGRA_2415Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. (151 aa)
SGRA_2416Transcriptional regulator, XRE family; COG1813 Predicted transcription factor, homolog of eukaryotic MBF1. (105 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (596 aa)
rpoE-9COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
SGRA_2480COG1309 Transcriptional regulator. (194 aa)
SGRA_2500Sigma54 specific transcriptional regulator, Fis family protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (433 aa)
SGRA_2521Hypothetical protein; COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit. (105 aa)
hupB-2COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family. (106 aa)
mutS2MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (800 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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