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SGRA_4204 SGRA_4204 uvrD-2 uvrD-2 rsmE rsmE ycaJ ycaJ smc smc SGRA_4031 SGRA_4031 SGRA_3885 SGRA_3885 SGRA_3855 SGRA_3855 SGRA_3854 SGRA_3854 SGRA_3847 SGRA_3847 SGRA_3715 SGRA_3715 recD recD SGRA_3694 SGRA_3694 SGRA_3690 SGRA_3690 SGRA_3669 SGRA_3669 lemA lemA comM comM murA murA SGRA_3562 SGRA_3562 rluD-3 rluD-3 bacA bacA SGRA_3310 SGRA_3310 SGRA_3305 SGRA_3305 SGRA_3271 SGRA_3271 gyrB gyrB ybeA ybeA recB recB iscS-2 iscS-2 SGRA_3202 SGRA_3202 SGRA_3182 SGRA_3182 SGRA_3152 SGRA_3152 SGRA_3139 SGRA_3139 SGRA_2995 SGRA_2995 SGRA_2989 SGRA_2989 ccmC ccmC rsmD rsmD SGRA_2910 SGRA_2910 vanX vanX SGRA_2831 SGRA_2831 SGRA_2786 SGRA_2786 murF murF dnaB dnaB SGRA_2715 SGRA_2715 rsgA rsgA SGRA_2689 SGRA_2689 ruvA ruvA SGRA_2669 SGRA_2669 era era ruvB ruvB comL comL rnc rnc SGRA_2491 SGRA_2491 rbfA rbfA SGRA_2446 SGRA_2446 SGRA_2434 SGRA_2434 SGRA_2387 SGRA_2387 SGRA_2328 SGRA_2328 SGRA_2267 SGRA_2267 prfA prfA SGRA_2214 SGRA_2214 SGRA_2198 SGRA_2198 SGRA_2172 SGRA_2172 murB murB SGRA_2156 SGRA_2156 ybeY ybeY SGRA_2122 SGRA_2122 typA typA recG recG SGRA_2076 SGRA_2076 mltD mltD SGRA_2058 SGRA_2058 SGRA_2052 SGRA_2052 SGRA_1984 SGRA_1984 engA engA SGRA_1972 SGRA_1972 SGRA_1969 SGRA_1969 SGRA_1961 SGRA_1961 gidB gidB ksgA ksgA SGRA_1902 SGRA_1902 prfC prfC SGRA_1884 SGRA_1884 iscU iscU iscS iscS SGRA_1870 SGRA_1870 ccmF ccmF SGRA_1796 SGRA_1796 frr frr SGRA_1707 SGRA_1707 mfd mfd SGRA_1638 SGRA_1638 SGRA_1605 SGRA_1605 recQ-2 recQ-2 parE parE prfB prfB hscB hscB SGRA_1459 SGRA_1459 SGRA_1366 SGRA_1366 rplT rplT rsfS rsfS SGRA_1217 SGRA_1217 SGRA_1214 SGRA_1214 SGRA_1151 SGRA_1151 rimP rimP SGRA_1113 SGRA_1113 ddl ddl ruvX ruvX SGRA_1038 SGRA_1038 SGRA_1023 SGRA_1023 recQ recQ SGRA_0976 SGRA_0976 rsmI rsmI engB engB rluF rluF parC parC ftsZ ftsZ murC murC murG murG murD murD mraY mraY murE murE ftsI ftsI mraW mraW topA topA SGRA_0830 SGRA_0830 pbpC pbpC SGRA_0775 SGRA_0775 SGRA_0769 SGRA_0769 priA priA SGRA_0714 SGRA_0714 SGRA_0673 SGRA_0673 SGRA_0671 SGRA_0671 obgE obgE SGRA_0599 SGRA_0599 gyrA gyrA hlpA-2 hlpA-2 hlpA hlpA SGRA_0503 SGRA_0503 SGRA_0494 SGRA_0494 rluB rluB yaeT yaeT mrdA mrdA SGRA_0387 SGRA_0387 SGRA_0380 SGRA_0380 SGRA_0369 SGRA_0369 mrp mrp murI murI ccmB ccmB cas1 cas1 SGRA_0275 SGRA_0275 rlmN rlmN SGRA_0221 SGRA_0221 rimM rimM SGRA_0181 SGRA_0181 SGRA_0178 SGRA_0178 mltG mltG rluE rluE SGRA_0015 SGRA_0015
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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SGRA_4204TPR repeat-containing protein; COG0457 FOG: TPR repeat. (1085 aa)
uvrD-2COG0210 Superfamily I DNA and RNA helicases. (759 aa)
rsmE16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (238 aa)
ycaJRecombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase. (424 aa)
smcChromosome segregation protein smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1173 aa)
SGRA_4031rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (363 aa)
SGRA_3885Hypothetical protein; COG1561 Uncharacterized stress-induced protein. (287 aa)
SGRA_3855Hypothetical protein. (163 aa)
SGRA_3854Hypothetical protein. (163 aa)
SGRA_3847TPR repeat-containing protein; COG4995 Uncharacterized protein conserved in bacteria. (524 aa)
SGRA_3715TPR repeat-containing protein; COG0457 FOG: TPR repeat. (1061 aa)
recDPutative exodeoxyribonuclease V; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. (762 aa)
SGRA_3694Putative lipoprotein. (291 aa)
SGRA_3690TPR repeat-containing protein; COG0457 FOG: TPR repeat. (1032 aa)
SGRA_3669Hypothetical protein; COG2217 Cation transport ATPase. (937 aa)
lemALemA family protein; COG0457 FOG: TPR repeat. (328 aa)
comMMg chelatase, subunit chli; COG0606 Predicted ATPase with chaperone activity. (518 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (439 aa)
SGRA_3562Hypothetical protein. (790 aa)
rluD-3Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (345 aa)
bacAPutative bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (320 aa)
SGRA_3310COG4232 Thiol:disulfide interchange protein. (852 aa)
SGRA_3305Hypothetical protein. (499 aa)
SGRA_3271Hypothetical protein. (92 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (658 aa)
ybeArRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (157 aa)
recBUvrD/REP helicase; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains). (1091 aa)
iscS-2COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (376 aa)
SGRA_3202Tetratricopeptide tpr_1 repeat-containing protein; COG0457 FOG: TPR repeat. (1013 aa)
SGRA_3182Tetratricopeptide tpr_1 repeat-containing protein; COG0457 FOG: TPR repeat. (836 aa)
SGRA_3152COG3210 Large exoproteins involved in heme utilization or adhesion. (103 aa)
SGRA_3139Zinc finger swim domain-containing protein. (446 aa)
SGRA_2995ErfK/YbiS/YcfS/YnhG family protein; COG3034 Uncharacterized protein conserved in bacteria. (244 aa)
SGRA_2989TPR repeat-containing protein; COG0457 FOG: TPR repeat. (1006 aa)
ccmCCOG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component. (349 aa)
rsmDMethyltransferase; COG0742 N6-adenine-specific methylase. (184 aa)
SGRA_2910Uroporphyrin-iii c/tetrapyrrole (corrin/porphyrin) methyltransferase; COG0313 Predicted methyltransferases. (235 aa)
vanXPeptidase m15d vanx d-ala-d-ala dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (258 aa)
SGRA_2831Tetratricopeptide tpr_1 repeat-containing protein; COG0457 FOG: TPR repeat. (926 aa)
SGRA_2786Hypothetical protein. (99 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. (437 aa)
dnaBPrimary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (510 aa)
SGRA_2715Hypothetical protein. (176 aa)
rsgAGTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (312 aa)
SGRA_2689Surface antigen (D15); COG0729 Outer membrane protein. (1042 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa)
SGRA_2669Putative organic solvent tolerance protein OstA. (966 aa)
eraGTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (299 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (341 aa)
comLOuter membrane assembly lipoprotein YfiO; COG4105 DNA uptake lipoprotein. (270 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (252 aa)
SGRA_2491Hypothetical protein. (474 aa)
rbfARibosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (135 aa)
SGRA_2446TPR repeat-containing protein; COG0457 FOG: TPR repeat. (1490 aa)
SGRA_2434Glycosyl transferase family 4; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase. (378 aa)
SGRA_2387Thioredoxin domain protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (295 aa)
SGRA_2328Putative disulfide-isomerase; COG0526 Thiol-disulfide isomerase and thioredoxins. (802 aa)
SGRA_2267COG2035 Predicted membrane protein. (302 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa)
SGRA_2214Hypothetical protein; COG1520 FOG: WD40-like repeat. (564 aa)
SGRA_2198COG0694 Thioredoxin-like proteins and domains. (207 aa)
SGRA_2172Hypothetical protein. (1718 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (332 aa)
SGRA_2156COG1843 Flagellar hook capping protein. (1660 aa)
ybeYHypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (145 aa)
SGRA_2122Hypothetical protein. (360 aa)
typAGTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response. (607 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (702 aa)
SGRA_2076Hypothetical protein; COG0457 FOG: TPR repeat. (689 aa)
mltDCOG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains). (600 aa)
SGRA_2058Hypothetical protein. (646 aa)
SGRA_2052COG1952 Preprotein translocase subunit SecB. (125 aa)
SGRA_1984TPR repeat-containing protein; COG0457 FOG: TPR repeat. (1153 aa)
engAGtp-binding protein enga; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (433 aa)
SGRA_1972Chromosome segregation ATPase-like protein. (1125 aa)
SGRA_1969Putative lipoprotein. (525 aa)
SGRA_1961Hypothetical protein. (307 aa)
gidBMethyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (210 aa)
ksgA16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (264 aa)
SGRA_1902Hypothetical protein. (421 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (526 aa)
SGRA_1884Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. (108 aa)
iscUFeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa)
iscSCysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (406 aa)
SGRA_1870Hypothetical protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. (138 aa)
ccmFCOG1138 Cytochrome c biogenesis factor. (836 aa)
SGRA_1796COG1952 Preprotein translocase subunit SecB. (145 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (187 aa)
SGRA_1707Outer membrane protein. (596 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1122 aa)
SGRA_1638ABC transporter related protein; COG1131 ABC-type multidrug transport system, ATPase component. (210 aa)
SGRA_1605Tetratricopeptide tpr_1 repeat-containing protein; COG0457 FOG: TPR repeat. (1000 aa)
recQ-2COG0514 Superfamily II DNA helicase. (737 aa)
parEDNA topoisomerase IV subunit B; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit. (616 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (334 aa)
hscBCo-chaperone Hsc20; COG1076 DnaJ-domain-containing proteins 1. (176 aa)
SGRA_1459COG0785 Cytochrome c biogenesis protein. (234 aa)
SGRA_1366Chromosome segregation ATPase-like protein; COG3210 Large exoproteins involved in heme utilization or adhesion. (109 aa)
rplTRibosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (115 aa)
rsfSIojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (130 aa)
SGRA_1217Hypothetical protein. (288 aa)
SGRA_1214Terminal quinol oxidase subunit. (340 aa)
SGRA_1151Nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (399 aa)
rimPHypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (162 aa)
SGRA_1113FeS assembly protein IscX; COG2975 Uncharacterized protein conserved in bacteria. (79 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (902 aa)
ruvXHolliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (171 aa)
SGRA_1038TPR repeat-containing protein; COG4995 Uncharacterized protein conserved in bacteria. (981 aa)
SGRA_1023RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (554 aa)
recQATP-dependent DNA helicase, RecQ family protein; COG0514 Superfamily II DNA helicase. (2930 aa)
SGRA_0976TPR repeat-containing protein; COG4995 Uncharacterized protein conserved in bacteria. (714 aa)
rsmIUroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (252 aa)
engBGTP-binding protein HSR1-related protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (202 aa)
rluFPutative ribosomal RNA pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. (234 aa)
parCCOG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit. (839 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (463 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (453 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (361 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (458 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (417 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (491 aa)
ftsIPeptidoglycan glycosyltransferase; COG0768 Cell division protein FtsI/penicillin-binding protein 2. (719 aa)
mraWS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (302 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (876 aa)
SGRA_0830Hypothetical protein. (239 aa)
pbpCPenicillin-binding protein 1C; COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC. (812 aa)
SGRA_0775TPR repeat-containing protein; COG0457 FOG: TPR repeat. (991 aa)
SGRA_0769Hypothetical protein. (356 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (839 aa)
SGRA_0714Hypothetical protein. (166 aa)
SGRA_0673Outer membrane chaperone Skp (OmpH); COG2825 Outer membrane protein. (168 aa)
SGRA_0671Hypothetical protein. (2397 aa)
obgEGTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (335 aa)
SGRA_0599COG0694 Thioredoxin-like proteins and domains. (82 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (858 aa)
hlpA-2Outer membrane chaperone Skp (OmpH); COG2825 Outer membrane protein. (155 aa)
hlpAOuter membrane chaperone Skp (OmpH); COG2825 Outer membrane protein. (171 aa)
SGRA_0503Outer membrane chaperone Skp (OmpH); COG2825 Outer membrane protein. (168 aa)
SGRA_0494Signal transduction histidine kinase, LytS; COG3275 Putative regulator of cell autolysis. (354 aa)
rluBPseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. (270 aa)
yaeTSurface antigen variable number repeat protein; COG4775 Outer membrane protein/protective antigen OMA87. (857 aa)
mrdAPeptidoglycan glycosyltransferase; COG0768 Cell division protein FtsI/penicillin-binding protein 2. (617 aa)
SGRA_0387Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. (119 aa)
SGRA_0380Pseudouridine synthase, Rsu; COG3210 Large exoproteins involved in heme utilization or adhesion. (110 aa)
SGRA_0369Lvivd repeat-containing protein. (430 aa)
mrpATP-binding protein, Mrp/Nbp35 family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (364 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (278 aa)
ccmBCOG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component. (220 aa)
cas1CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (321 aa)
SGRA_0275COG1343 Uncharacterized protein predicted to be involved in DNA repair. (98 aa)
rlmNRibosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (348 aa)
SGRA_0221ABC transporter related protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components. (212 aa)
rimM16S rRNA processing protein rimm; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (171 aa)
SGRA_0181AAA ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. (427 aa)
SGRA_0178Signal transduction histidine kinase, LytS; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain. (352 aa)
mltGAminodeoxychorismate lyase family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (353 aa)
rluEPseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. (199 aa)
SGRA_0015Calcium-binding EF-hand-containing protein; COG5126 Ca2+-binding protein (EF-Hand superfamily). (150 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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