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dnaN dnaN dnaX dnaX SGRA_1023 SGRA_1023 nrdA nrdA SGRA_0925 SGRA_0925 dpx dpx SGRA_0403 SGRA_0403 SGRA_0401 SGRA_0401 SGRA_0400 SGRA_0400 holB holB SGRA_2572 SGRA_2572 sprA sprA SGRA_2901 SGRA_2901 SGRA_2984 SGRA_2984 SGRA_3037 SGRA_3037 SGRA_3038 SGRA_3038 SGRA_3257 SGRA_3257 holA holA SGRA_3404 SGRA_3404 dnaE dnaE polA polA SGRA_3606 SGRA_3606 tdk tdk SGRA_3869 SGRA_3869 apaG apaG SGRA_3894 SGRA_3894 SGRA_4131 SGRA_4131
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaNDNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (593 aa)
SGRA_1023RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (554 aa)
nrdARibonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (803 aa)
SGRA_0925Polysaccharide biosynthesis protein; COG0417 DNA polymerase elongation subunit (family B). (140 aa)
dpxPHP domain protein; COG1796 DNA polymerase IV (family X). (556 aa)
SGRA_0403AAA ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (440 aa)
SGRA_0401SMC domain protein; COG3950 Predicted ATP-binding protein involved in virulence. (532 aa)
SGRA_0400AAA ATPase. (287 aa)
holBCOG2812 DNA polymerase III, gamma/tau subunits. (385 aa)
SGRA_2572SMC domain protein; COG4637 Predicted ATPase. (454 aa)
sprAGliding motility protein SprA. (2512 aa)
SGRA_2901Hypothetical protein; COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA. (678 aa)
SGRA_2984AAA ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (399 aa)
SGRA_3037SMC domain protein; COG1122 ABC-type cobalt transport system, ATPase component. (620 aa)
SGRA_3038Hypothetical protein; COG1403 Restriction endonuclease. (319 aa)
SGRA_3257Hypothetical protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. (371 aa)
holACOG1466 DNA polymerase III, delta subunit. (356 aa)
SGRA_3404ATPase-like protein; COG4637 Predicted ATPase. (354 aa)
dnaECOG0587 DNA polymerase III, alpha subunit. (1176 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (927 aa)
SGRA_3606Hypothetical protein. (429 aa)
tdkCOG1435 Thymidine kinase. (184 aa)
SGRA_3869SMC domain-containing protein; COG3950 Predicted ATP-binding protein involved in virulence. (433 aa)
apaGCo2+/Mg2+ efflux protein ApaG; COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. (129 aa)
SGRA_3894SMC domain-containing protein; COG3950 Predicted ATP-binding protein involved in virulence. (441 aa)
SGRA_4131ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (751 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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