23 items (Saprospira grandis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	rpoA	DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (332 aa)
	dnaG	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (683 aa)
	dnaX	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (593 aa)
	mcrB	ATPase associated with various cellular activities AAA_5; COG1401 GTPase subunit of restriction endonuclease. (549 aa)
	SGRA_0949	COG1722 Exonuclease VII small subunit. (65 aa)
	SGRA_0925	Polysaccharide biosynthesis protein; COG0417 DNA polymerase elongation subunit (family B). (140 aa)
	SGRA_0306	TPR repeat-containing protein; COG1401 GTPase subunit of restriction endonuclease. (825 aa)
	SGRA_0305	COG4268 McrBC 5-methylcytosine restriction system component. (408 aa)
	SGRA_4129	Hypothetical protein. (137 aa)
	SGRA_3981	Hypothetical protein. (223 aa)
	xseA	COG1570 Exonuclease VII, large subunit; Belongs to the XseA family. (399 aa)
	recD	Putative exodeoxyribonuclease V; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. (762 aa)
	clpX	Sigma 54 interacting domain protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (419 aa)
	holA	COG1466 DNA polymerase III, delta subunit. (356 aa)
	SGRA_0100	COG4268 McrBC 5-methylcytosine restriction system component. (398 aa)
	rpoN	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog. (539 aa)
	SGRA_3138	Hypothetical protein. (509 aa)
	SGRA_2546	DNA-directed RNA polymerase, omega subunit. (113 aa)
	rpoC	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1420 aa)
	rpoB	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1276 aa)
	holB	COG2812 DNA polymerase III, gamma/tau subunits. (385 aa)
	SGRA_0181	AAA ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. (427 aa)
	dnaN	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa)

Your Current Organism:

Saprospira grandis

NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SGRA_0100	SGRA_0306	SGRA_0100	SGRA_0306	COG4268 McrBC 5-methylcytosine restriction system component.	TPR repeat-containing protein; COG1401 GTPase subunit of restriction endonuclease.	0.925
SGRA_0100	SGRA_4129	SGRA_0100	SGRA_4129	COG4268 McrBC 5-methylcytosine restriction system component.	Hypothetical protein.	0.684
SGRA_0100	mcrB	SGRA_0100	SGRA_1075	COG4268 McrBC 5-methylcytosine restriction system component.	ATPase associated with various cellular activities AAA_5; COG1401 GTPase subunit of restriction endonuclease.	0.925
SGRA_0181	dnaN	SGRA_0181	SGRA_1874	AAA ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.621
SGRA_0305	SGRA_0306	SGRA_0305	SGRA_0306	COG4268 McrBC 5-methylcytosine restriction system component.	TPR repeat-containing protein; COG1401 GTPase subunit of restriction endonuclease.	0.981
SGRA_0305	SGRA_4129	SGRA_0305	SGRA_4129	COG4268 McrBC 5-methylcytosine restriction system component.	Hypothetical protein.	0.684
SGRA_0305	mcrB	SGRA_0305	SGRA_1075	COG4268 McrBC 5-methylcytosine restriction system component.	ATPase associated with various cellular activities AAA_5; COG1401 GTPase subunit of restriction endonuclease.	0.925
SGRA_0306	SGRA_0100	SGRA_0306	SGRA_0100	TPR repeat-containing protein; COG1401 GTPase subunit of restriction endonuclease.	COG4268 McrBC 5-methylcytosine restriction system component.	0.925
SGRA_0306	SGRA_0305	SGRA_0306	SGRA_0305	TPR repeat-containing protein; COG1401 GTPase subunit of restriction endonuclease.	COG4268 McrBC 5-methylcytosine restriction system component.	0.981
SGRA_0925	dnaN	SGRA_0925	SGRA_1874	Polysaccharide biosynthesis protein; COG0417 DNA polymerase elongation subunit (family B).	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.973
SGRA_0949	xseA	SGRA_0949	SGRA_3760	COG1722 Exonuclease VII small subunit.	COG1570 Exonuclease VII, large subunit; Belongs to the XseA family.	0.997
SGRA_2546	SGRA_3138	SGRA_2546	SGRA_3138	DNA-directed RNA polymerase, omega subunit.	Hypothetical protein.	0.745
SGRA_2546	holA	SGRA_2546	SGRA_3263	DNA-directed RNA polymerase, omega subunit.	COG1466 DNA polymerase III, delta subunit.	0.471
SGRA_2546	holB	SGRA_2546	SGRA_2081	DNA-directed RNA polymerase, omega subunit.	COG2812 DNA polymerase III, gamma/tau subunits.	0.482
SGRA_2546	rpoA	SGRA_2546	SGRA_1819	DNA-directed RNA polymerase, omega subunit.	DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.994
SGRA_2546	rpoB	SGRA_2546	SGRA_2310	DNA-directed RNA polymerase, omega subunit.	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.987
SGRA_2546	rpoC	SGRA_2546	SGRA_2312	DNA-directed RNA polymerase, omega subunit.	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.972
SGRA_2546	rpoN	SGRA_2546	SGRA_3245	DNA-directed RNA polymerase, omega subunit.	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog.	0.838
SGRA_3138	SGRA_2546	SGRA_3138	SGRA_2546	Hypothetical protein.	DNA-directed RNA polymerase, omega subunit.	0.745
SGRA_3138	rpoA	SGRA_3138	SGRA_1819	Hypothetical protein.	DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.735