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| | SGRA_4128 | COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases. (1036 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (672 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (423 aa) |
| | SGRA_4031 | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (363 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (264 aa) |
| | trmD | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (226 aa) |
| | SGRA_3976 | Hypothetical protein. (461 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (658 aa) |
| | uvrD-2 | COG0210 Superfamily I DNA and RNA helicases. (759 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (376 aa) |
| | argS | COG0018 Arginyl-tRNA synthetase. (644 aa) |
| | SGRA_4160 | COG2963 Transposase and inactivated derivatives. (140 aa) |
| | ycaJ | Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase. (424 aa) |
| | SGRA_3913 | Transposase, is4 family protein; COG3666 Transposase and inactivated derivatives. (554 aa) |
| | leuS | COG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (939 aa) |
| | hsdR-3 | Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1070 aa) |
| | SGRA_3889 | Transposase, mutator type; COG3328 Transposase and inactivated derivatives. (398 aa) |
| | SGRA_3885 | Hypothetical protein; COG1561 Uncharacterized stress-induced protein. (287 aa) |
| | SGRA_3877 | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. (414 aa) |
| | SGRA_3864 | Transposase, is4 family protein; COG3666 Transposase and inactivated derivatives. (554 aa) |
| | SGRA_3849 | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. (460 aa) |
| | xseA | COG1570 Exonuclease VII, large subunit; Belongs to the XseA family. (399 aa) |
| | recD | Putative exodeoxyribonuclease V; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. (762 aa) |
| | recQ-3 | ATP-dependent DNA helicase, RecQ family protein; COG0514 Superfamily II DNA helicase. (654 aa) |
| | holA | COG1466 DNA polymerase III, delta subunit. (356 aa) |
| | SGRA_3580 | COG3666 Transposase and inactivated derivatives. (282 aa) |
| | SGRA_3579 | Transposase, is4 family protein; COG3666 Transposase and inactivated derivatives. (236 aa) |
| | sms | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (464 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (927 aa) |
| | phrB-2 | COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (445 aa) |
| | SGRA_0074 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (330 aa) |
| | queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (352 aa) |
| | rluE | Pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. (199 aa) |
| | SGRA_0100 | COG4268 McrBC 5-methylcytosine restriction system component. (398 aa) |
| | SGRA_0113 | COG2963 Transposase and inactivated derivatives. (140 aa) |
| | SGRA_0118 | Transposase, is4 family protein; COG3666 Transposase and inactivated derivatives. (554 aa) |
| | SGRA_0181 | AAA ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. (427 aa) |
| | SGRA_0199 | COG0392 Predicted integral membrane protein. (397 aa) |
| | rlmN | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (348 aa) |
| | SGRA_0275 | COG1343 Uncharacterized protein predicted to be involved in DNA repair. (98 aa) |
| | cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (321 aa) |
| | hsdR | Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification. (936 aa) |
| | SGRA_0305 | COG4268 McrBC 5-methylcytosine restriction system component. (408 aa) |
| | nfi | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (229 aa) |
| | SGRA_0347 | COG2963 Transposase and inactivated derivatives. (140 aa) |
| | rluB | Pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. (270 aa) |
| | xerD | Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (303 aa) |
| | SGRA_0534 | Transposase, mutator type; Required for the transposition of the insertion element. (362 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (858 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (304 aa) |
| | SGRA_0580 | Hypothetical protein; COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases. (153 aa) |
| | dpx | PHP domain protein; COG1796 DNA polymerase IV (family X). (556 aa) |
| | tatD | Hydrolase, TatD family protein; COG0084 Mg-dependent DNase. (272 aa) |
| | SGRA_0622 | COG0392 Predicted integral membrane protein. (382 aa) |
| | SGRA_0702 | 23S rRNA (uracil-5-)-methyltransferase RumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (501 aa) |
| | rnr | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (986 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (839 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (241 aa) |
| | ung | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (226 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (227 aa) |
| | SGRA_0849 | COG1112 Superfamily I DNA and RNA helicases and helicase subunits. (1342 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (876 aa) |
| | mraW | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (302 aa) |
| | SGRA_0891 | Transposase, is4 family protein; COG3666 Transposase and inactivated derivatives. (554 aa) |
| | parC | COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit. (839 aa) |
| | cysS | COG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (556 aa) |
| | rluF | Putative ribosomal RNA pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. (234 aa) |
| | rsmI | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (252 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (596 aa) |
| | SGRA_0949 | COG1722 Exonuclease VII small subunit. (65 aa) |
| | recQ | ATP-dependent DNA helicase, RecQ family protein; COG0514 Superfamily II DNA helicase. (2930 aa) |
| | truC | COG0564 Pseudouridylate synthases, 23S RNA-specific. (296 aa) |
| | pth | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (226 aa) |
| | SGRA_1023 | RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (554 aa) |
| | SGRA_1025 | ATP-dependent DNA ligase. (1056 aa) |
| | SGRA_1184 | COG2963 Transposase and inactivated derivatives. (140 aa) |
| | SGRA_1191 | COG2963 Transposase and inactivated derivatives. (140 aa) |
| | phrB | COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (466 aa) |
| | SGRA_1262 | Hypothetical protein; COG0500 SAM-dependent methyltransferases. (391 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (593 aa) |
| | SGRA_1322 | COG2963 Transposase and inactivated derivatives. (140 aa) |
| | uvrC | Uvrabc system protein c; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (603 aa) |
| | SGRA_1339 | COG0566 rRNA methylases. (145 aa) |
| | SGRA_1346 | Hypothetical protein. (1035 aa) |
| | SGRA_1355 | Smr protein/MutS2; COG1193 Mismatch repair ATPase (MutS family). (365 aa) |
| | SGRA_1364 | DNA helicase; COG1112 Superfamily I DNA and RNA helicases and helicase subunits. (1127 aa) |
| | SGRA_1411 | Transposase, mutator type; Required for the transposition of the insertion element. (398 aa) |
| | lysS | COG1190 Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family. (545 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1123 aa) |
| | parE | DNA topoisomerase IV subunit B; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit. (616 aa) |
| | recQ-2 | COG0514 Superfamily II DNA helicase. (737 aa) |
| | SGRA_1633 | AAA ATPase; COG1112 Superfamily I DNA and RNA helicases and helicase subunits. (637 aa) |
| | glnS | COG0008 Glutamyl- and glutaminyl-tRNA synthetases. (577 aa) |
| | serS | COG0172 Seryl-tRNA synthetase. (427 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (589 aa) |
| | rnpA | Ribonuclease p protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (133 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1122 aa) |
| | SGRA_1671 | Transposase, mutator type; COG3328 Transposase and inactivated derivatives. (398 aa) |
| | rluD | Ribosomal large subunit pseudouridine synthase d; COG0564 Pseudouridylate synthases, 23S RNA-specific. (241 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (683 aa) |
| | SGRA_1751 | Hypothetical protein. (256 aa) |
| | uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (680 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (152 aa) |
| | rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (332 aa) |
| | dnaN | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa) |
| | SGRA_1881 | RNA methyltransferase YjfH; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (250 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (901 aa) |
| | ksgA | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (264 aa) |
| | gidB | Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (210 aa) |
| | asnS | COG0017 Aspartyl/asparaginyl-tRNA synthetases. (508 aa) |
| | SGRA_1973 | Hypothetical protein. (325 aa) |
| | ruvC | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (177 aa) |
| | recA | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (372 aa) |
| | holB | COG2812 DNA polymerase III, gamma/tau subunits. (385 aa) |
| | pheS | COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (345 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (702 aa) |
| | rnhA | Putative ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family. (209 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (884 aa) |
| | ybeY | Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (145 aa) |
| | SGRA_2155 | Transposase, is4 family protein; COG3666 Transposase and inactivated derivatives. (554 aa) |
| | yjfH | RNA methyltransferase, TrmH family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (239 aa) |
| | mutY | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (402 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (510 aa) |
| | glyS1 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (519 aa) |
| | SGRA_2251 | DNA mismatch repair protein MutS domain-containing protein; COG0249 Mismatch repair ATPase (MutS family). (589 aa) |
| | trpS | COG0180 Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (338 aa) |
| | SGRA_2288 | ADP-ribosylation/crystallin J1. (393 aa) |
| | rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1276 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1420 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (466 aa) |
| | hisS | COG0124 Histidyl-tRNA synthetase. (465 aa) |
| | SGRA_2367 | COG0500 SAM-dependent methyltransferases. (399 aa) |
| | dcm | DNA-cytosine methyltransferase; COG0270 Site-specific DNA methylase. (418 aa) |
| | SGRA_2491 | Hypothetical protein. (474 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (252 aa) |
| | SGRA_2546 | DNA-directed RNA polymerase, omega subunit. (113 aa) |
| | rng | COG1530 Ribonucleases G and E. (520 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (205 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (341 aa) |
| | xthA | Exodeoxyribonuclease III Xth; COG0708 Exonuclease III. (257 aa) |
| | mutS2 | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (800 aa) |
| | ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa) |
| | sprA | Gliding motility protein SprA. (2512 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa) |
| | spoU | tRNA/rRNA methyltransferase (SpoU); COG0566 rRNA methylases. (252 aa) |
| | dnaB | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (510 aa) |
| | SGRA_2735 | Transposase, mutator type; COG3328 Transposase and inactivated derivatives. (398 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (493 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (831 aa) |
| | rny | Phosphodiesterase; Endoribonuclease that initiates mRNA decay. (545 aa) |
| | SGRA_2790 | Hypothetical protein. (1159 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (875 aa) |
| | trmB | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (226 aa) |
| | ebsC | ybaK/ebsC protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (157 aa) |
| | mutL | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (622 aa) |
| | deaD | DEAD/DEAH box helicase domain protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. (474 aa) |
| | miaE | tRNA-hydroxylase; COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA. (200 aa) |
| | SGRA_2969 | Putative SpoU rRNA methylase family protein; COG0566 rRNA methylases. (179 aa) |
| | SGRA_3008 | Transposase, mutator type; COG3328 Transposase and inactivated derivatives. (398 aa) |
| | rluD-2 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (245 aa) |
| | SGRA_3132 | Transposase, mutator type; COG3328 Transposase and inactivated derivatives. (398 aa) |
| | SGRA_3151 | Transposase, mutator type; COG3328 Transposase and inactivated derivatives. (398 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (724 aa) |
| | recB | UvrD/REP helicase; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains). (1091 aa) |
| | ybeA | rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (157 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (307 aa) |
| | SGRA_3455 | COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (206 aa) |
| | SGRA_3429 | Putative DNA-binding protein; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). (237 aa) |
| | dnaE | COG0587 DNA polymerase III, alpha subunit. (1176 aa) |
| | SGRA_3413 | COG1943 Transposase and inactivated derivatives. (142 aa) |
| | hsdR-2 | COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases. (1132 aa) |
| | rluD-3 | Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (345 aa) |
| | ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (710 aa) |
| | SGRA_3284 | Hypothetical protein; COG1002 Type II restriction enzyme, methylase subunits. (1295 aa) |
| | SGRA_3264 | Hypothetical protein. (205 aa) |
