STRINGSTRING
SGRA_4209 SGRA_4209 SGRA_0031 SGRA_0031 lon lon gcvT gcvT kynU kynU SGRA_0693 SGRA_0693 SGRA_0759 SGRA_0759 SGRA_0842 SGRA_0842 SGRA_0843 SGRA_0843 gabD gabD SGRA_0982 SGRA_0982 speA speA astE astE tdcF tdcF SGRA_1189 SGRA_1189 mtnN mtnN ftsH ftsH hutH hutH ampC-2 ampC-2 clpS clpS aat aat ggt ggt hutU hutU dtd dtd SGRA_1893 SGRA_1893 SGRA_1937 SGRA_1937 ald ald amiA amiA SGRA_2068 SGRA_2068 gldH gldH hutI hutI SGRA_2469 SGRA_2469 SGRA_2545 SGRA_2545 SGRA_2632 SGRA_2632 sucB sucB cdd cdd pepT pepT gcvH gcvH acm acm SGRA_3129 SGRA_3129 SGRA_3134 SGRA_3134 gcvP gcvP surE surE SGRA_3198 SGRA_3198 pncA pncA SGRA_3474 SGRA_3474 SGRA_3525 SGRA_3525 amn amn hmgA hmgA mazG mazG dut dut SGRA_3965 SGRA_3965 SGRA_3989 SGRA_3989 ggt-2 ggt-2 SGRA_4174 SGRA_4174
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SGRA_4209Cyclase family protein; COG1878 Predicted metal-dependent hydrolase. (256 aa)
SGRA_0031COG3643 Glutamate formiminotransferase. (561 aa)
lonATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (804 aa)
gcvTGlycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (368 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (425 aa)
SGRA_0693Hypothetical protein. (126 aa)
SGRA_0759Dipeptidyl-peptidase 7; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. (711 aa)
SGRA_0842Amidohydrolase; COG1228 Imidazolonepropionase and related amidohydrolases. (430 aa)
SGRA_0843Amidohydrolase; COG1228 Imidazolonepropionase and related amidohydrolases. (1008 aa)
gabDCOG1012 NAD-dependent aldehyde dehydrogenases. (453 aa)
SGRA_0982COG0686 Alanine dehydrogenase. (403 aa)
speAOrn/DAP/Arg decarboxylase 2; COG1166 Arginine decarboxylase (spermidine biosynthesis). (465 aa)
astESuccinylglutamate desuccinylase/aspartoacylase family protein; COG2988 Succinylglutamate desuccinylase. (333 aa)
tdcFEndoribonuclease L-PSP; COG0251 Putative translation initiation inhibitor, yjgF family. (214 aa)
SGRA_1189Amidohydrolase 3; COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold. (564 aa)
mtnNPurine or other phosphorylase family 1; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (227 aa)
ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (675 aa)
hutHCOG2986 Histidine ammonia-lyase. (500 aa)
ampC-2COG2367 Beta-lactamase class A. (350 aa)
clpSATP-dependent Clp protease adaptor protein ClpS; Belongs to the ClpS family. (101 aa)
aatLeucyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. (235 aa)
ggtCOG0405 Gamma-glutamyltransferase. (560 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (672 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (152 aa)
SGRA_1893COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (506 aa)
SGRA_1937COG0506 Proline dehydrogenase. (362 aa)
aldCOG0686 Alanine dehydrogenase. (407 aa)
amiACell wall hydrolase/autolysin; COG0860 N-acetylmuramoyl-L-alanine amidase. (367 aa)
SGRA_2068Metal dependent phosphohydrolase; COG1078 HD superfamily phosphohydrolases. (406 aa)
gldHGliding motility protein GldH. (163 aa)
hutICOG1228 Imidazolonepropionase and related amidohydrolases. (418 aa)
SGRA_2469COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (517 aa)
SGRA_2545Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (413 aa)
SGRA_2632COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (471 aa)
sucB2-oxoglutarate dehydrogenase, e2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (420 aa)
cddCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (161 aa)
pepTPeptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (409 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
acmGlycoside hydrolase family 25; COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase). (218 aa)
SGRA_3129COG1231 Monoamine oxidase. (447 aa)
SGRA_3134Hypothetical protein; COG0804 Urea amidohydrolase (urease) alpha subunit. (490 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (975 aa)
surE5'(3')-nucleotidase/polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (256 aa)
SGRA_3198Hypothetical protein. (306 aa)
pncANicotinamidase; COG1335 Amidases related to nicotinamidase. (207 aa)
SGRA_3474N-formylkynurenine (aryl-) formamidase. (254 aa)
SGRA_3525COG1012 NAD-dependent aldehyde dehydrogenases. (542 aa)
amnAMP nucleosidase; COG0775 Nucleoside phosphorylase. (257 aa)
hmgACOG3508 Homogentisate 1,2-dioxygenase. (386 aa)
mazGNucleoside triphosphate pyrophosphohydrolase; COG1694 Predicted pyrophosphatase. (254 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa)
SGRA_3965COG4539 Predicted membrane protein. (160 aa)
SGRA_3989phytanoyl-CoA dioxygenase. (315 aa)
ggt-2Gamma-glutamyltranspeptidase small chain; COG0405 Gamma-glutamyltransferase. (491 aa)
SGRA_4174Cell wall hydrolase/autolysin; COG0860 N-acetylmuramoyl-L-alanine amidase. (385 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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