47 items (Saprospira grandis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dnaG	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (683 aa)
	rpoE-7	RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
	SGRA_1804	COG0818 Diacylglycerol kinase. (125 aa)
	rpoA	DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (332 aa)
	prfC	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (526 aa)
	SGRA_2152	COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). (135 aa)
	radC	COG2003 DNA repair proteins; Belongs to the UPF0758 family. (242 aa)
	SGRA_2285	RNA polymerase sigma factor, sigma-70 family protein; COG1191 DNA-directed RNA polymerase specialized sigma subunit. (199 aa)
	rpoB	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1276 aa)
	rpoC	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1420 aa)
	SGRA_2395	ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (200 aa)
	rpoE-8	RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
	rpoE-9	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
	SGRA_2546	DNA-directed RNA polymerase, omega subunit. (113 aa)
	comL	Outer membrane assembly lipoprotein YfiO; COG4105 DNA uptake lipoprotein. (270 aa)
	rpmA	COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (90 aa)
	SGRA_2874	Hypothetical protein. (369 aa)
	ftsK	COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins. (850 aa)
	SGRA_3207	Transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (239 aa)
	SGRA_3212	Switch protein/serine-threonine kinase; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). (132 aa)
	SGRA_3213	Putative anti-sigma regulatory factor, serine/threonine protein kinase; COG0656 Aldo/keto reductases, related to diketogulonate reductase. (200 aa)
	rpoN	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog. (539 aa)
	rpoE-10	RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
	nadE	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (545 aa)
	dnaE	COG0587 DNA polymerase III, alpha subunit. (1176 aa)
	SGRA_3474	N-formylkynurenine (aryl-) formamidase. (254 aa)
	SGRA_3662	Hypothetical protein. (278 aa)
	SGRA_3663	Hypothetical protein. (270 aa)
	hsdS-2	COG0732 Restriction endonuclease S subunits. (385 aa)
	SGRA_3981	Hypothetical protein. (223 aa)
	hsdS-3	Type I restriction-modification system; COG0732 Restriction endonuclease S subunits. (430 aa)
	rpoE-11	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (201 aa)
	SGRA_4209	Cyclase family protein; COG1878 Predicted metal-dependent hydrolase. (256 aa)
	SGRA_0955	Hypothetical protein. (261 aa)
	rpoE-3	RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (152 aa)
	rpoE-4	RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
	SGRA_1061	Hypothetical protein. (144 aa)
	SGRA_1375	RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
	rpoE-5	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (213 aa)
	rpoE-6	RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa)
	rpoS	Putative RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (290 aa)
	SGRA_0197	RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
	rpoE	RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (172 aa)
	SGRA_0626	COG5343 Uncharacterized protein conserved in bacteria. (281 aa)
	rpoE-2	RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
	SGRA_1732	RNA polymerase, sigma-E factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)
	rpoD	RNA polymerase, sigma 70 subunit, RpoD subfamily protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (290 aa)

Your Current Organism:

Saprospira grandis

NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SGRA_0626	rpoE	SGRA_0626	SGRA_0625	COG5343 Uncharacterized protein conserved in bacteria.	RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.903
SGRA_1375	SGRA_2285	SGRA_1375	SGRA_2285	RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase sigma factor, sigma-70 family protein; COG1191 DNA-directed RNA polymerase specialized sigma subunit.	0.730
SGRA_1375	SGRA_2546	SGRA_1375	SGRA_2546	RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	DNA-directed RNA polymerase, omega subunit.	0.457
SGRA_1732	rpoE-10	SGRA_1732	SGRA_3277	RNA polymerase, sigma-E factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.624
SGRA_1732	rpoE-3	SGRA_1732	SGRA_1035	RNA polymerase, sigma-E factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.482
SGRA_1732	rpoE-5	SGRA_1732	SGRA_1614	RNA polymerase, sigma-E factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.472
SGRA_2152	rpoE-11	SGRA_2152	SGRA_4178	COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.430
SGRA_2285	SGRA_1375	SGRA_2285	SGRA_1375	RNA polymerase sigma factor, sigma-70 family protein; COG1191 DNA-directed RNA polymerase specialized sigma subunit.	RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.730
SGRA_2395	rpoE-5	SGRA_2395	SGRA_1614	ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.761
SGRA_2395	rpoE-6	SGRA_2395	SGRA_1620	ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.743
SGRA_2546	SGRA_1375	SGRA_2546	SGRA_1375	DNA-directed RNA polymerase, omega subunit.	RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.457
SGRA_2546	comL	SGRA_2546	SGRA_2547	DNA-directed RNA polymerase, omega subunit.	Outer membrane assembly lipoprotein YfiO; COG4105 DNA uptake lipoprotein.	0.986
SGRA_2546	rpmA	SGRA_2546	SGRA_2701	DNA-directed RNA polymerase, omega subunit.	COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.767
SGRA_2546	rpoA	SGRA_2546	SGRA_1819	DNA-directed RNA polymerase, omega subunit.	DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.994
SGRA_2546	rpoB	SGRA_2546	SGRA_2310	DNA-directed RNA polymerase, omega subunit.	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.987
SGRA_2546	rpoC	SGRA_2546	SGRA_2312	DNA-directed RNA polymerase, omega subunit.	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.972
SGRA_2546	rpoD	SGRA_2546	SGRA_0788	DNA-directed RNA polymerase, omega subunit.	RNA polymerase, sigma 70 subunit, RpoD subfamily protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.733
SGRA_2546	rpoN	SGRA_2546	SGRA_3245	DNA-directed RNA polymerase, omega subunit.	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog.	0.838
SGRA_2546	rpoS	SGRA_2546	SGRA_1646	DNA-directed RNA polymerase, omega subunit.	Putative RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.733
SGRA_3207	SGRA_3212	SGRA_3207	SGRA_3212	Transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.	Switch protein/serine-threonine kinase; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).	0.414