16 items (Saprospira grandis) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	SGRA_4190	COG1607 Acyl-CoA hydrolase. (163 aa)
	SGRA_1937	COG0506 Proline dehydrogenase. (362 aa)
	ilvE	COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (362 aa)
	fdx-2	COG0633 Ferredoxin. (108 aa)
	SGRA_2540	Hypothetical protein. (121 aa)
	pdhB	Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa)
	fixB	COG2025 Electron transfer flavoprotein, alpha subunit. (319 aa)
	iscS-2	COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (376 aa)
	acs	Acetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (633 aa)
	SGRA_0034	Putative metallopeptidase, M16 family protein. (336 aa)
	prpE	prpE protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (627 aa)
	SGRA_0713	Thioesterase superfamily protein; COG1607 Acyl-CoA hydrolase. (172 aa)
	crt	COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
	rpsB	COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (241 aa)
	SGRA_1859	Thioesterase superfamily protein; COG1607 Acyl-CoA hydrolase. (128 aa)
	iscS	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (406 aa)

Your Current Organism:

Saprospira grandis

NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SGRA_1937	acs	SGRA_1937	SGRA_3448	COG0506 Proline dehydrogenase.	Acetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.445
SGRA_1937	prpE	SGRA_1937	SGRA_0656	COG0506 Proline dehydrogenase.	prpE protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.	0.445
SGRA_2540	rpsB	SGRA_2540	SGRA_1597	Hypothetical protein.	COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.694
acs	SGRA_1937	SGRA_3448	SGRA_1937	Acetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	COG0506 Proline dehydrogenase.	0.445
acs	crt	SGRA_3448	SGRA_1167	Acetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.571
acs	pdhB	SGRA_3448	SGRA_2542	Acetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.816
acs	prpE	SGRA_3448	SGRA_0656	Acetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	prpE protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.	0.911
crt	acs	SGRA_1167	SGRA_3448	COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.571
crt	fixB	SGRA_1167	SGRA_3123	COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.	COG2025 Electron transfer flavoprotein, alpha subunit.	0.614
crt	prpE	SGRA_1167	SGRA_0656	COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.	prpE protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.	0.447
crt	rpsB	SGRA_1167	SGRA_1597	COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.	COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.571
fdx-2	iscS	SGRA_2393	SGRA_1882	COG0633 Ferredoxin.	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	0.634
fdx-2	iscS-2	SGRA_2393	SGRA_3206	COG0633 Ferredoxin.	COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.	0.634
fixB	crt	SGRA_3123	SGRA_1167	COG2025 Electron transfer flavoprotein, alpha subunit.	COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.614
fixB	pdhB	SGRA_3123	SGRA_2542	COG2025 Electron transfer flavoprotein, alpha subunit.	Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.486
iscS	fdx-2	SGRA_1882	SGRA_2393	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	COG0633 Ferredoxin.	0.634
iscS	iscS-2	SGRA_1882	SGRA_3206	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.	0.916
iscS-2	fdx-2	SGRA_3206	SGRA_2393	COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.	COG0633 Ferredoxin.	0.634
iscS-2	iscS	SGRA_3206	SGRA_1882	COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	0.916
pdhB	acs	SGRA_2542	SGRA_3448	Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Acetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.816