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| | ychF | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (367 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (435 aa) |
| | SGRA_0005 | COG1748 Saccharopine dehydrogenase and related proteins. (452 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (262 aa) |
| | fbaB | COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes. (350 aa) |
| | SGRA_0043 | Type 4 fimbriae expression regulatory protein pilR; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (549 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (494 aa) |
| | queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (352 aa) |
| | SGRA_0096 | Hypothetical protein. (247 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | rluE | Pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. (199 aa) |
| | ribE | COG0307 Riboflavin synthase alpha chain. (198 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa) |
| | SGRA_0112 | Integrase catalytic region; COG2801 Transposase and inactivated derivatives. (251 aa) |
| | groEL | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (546 aa) |
| | mdaB | NAD(P)H dehydrogenase (quinone); COG2249 Putative NADPH-quinone reductase (modulator of drug activity B). (197 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (537 aa) |
| | uppS | Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (259 aa) |
| | rimM | 16S rRNA processing protein rimm; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (171 aa) |
| | pepP | COG0006 Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family. (466 aa) |
| | kdsC | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). (174 aa) |
| | rlmN | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (348 aa) |
| | SGRA_0279 | Band 7 protein; COG0330 Membrane protease subunits, stomatin/prohibitin homologs. (314 aa) |
| | SGRA_0301 | Antibiotic biosynthesis monooxygenase. (99 aa) |
| | speE | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (399 aa) |
| | SGRA_0334 | Integrase catalytic region; COG2801 Transposase and inactivated derivatives. (167 aa) |
| | SGRA_0335 | Transposase IS3/IS911 family protein; COG2963 Transposase and inactivated derivatives. (95 aa) |
| | SGRA_0348 | IS3 family transposase; COG2801 Transposase and inactivated derivatives. (55 aa) |
| | SGRA_0349 | ISPg5, transposase Orf2; COG2801 Transposase and inactivated derivatives. (92 aa) |
| | fabD | COG0331 (acyl-carrier-protein) S-malonyltransferase. (293 aa) |
| | SGRA_0387 | Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. (119 aa) |
| | SGRA_0414 | COG0542 ATPases with chaperone activity, ATP-binding subunit. (753 aa) |
| | SGRA_0446 | Integrase catalytic region; COG2801 Transposase and inactivated derivatives. (193 aa) |
| | SGRA_0447 | Transposase IS3/IS911 family protein; COG2963 Transposase and inactivated derivatives. (95 aa) |
| | rluB | Pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. (270 aa) |
| | gloA | methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. (133 aa) |
| | clpC | ATPase AAA-2 domain protein; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (847 aa) |
| | SGRA_0580 | Hypothetical protein; COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases. (153 aa) |
| | SGRA_0583 | Xylose isomerase domain-containing protein; COG1082 Sugar phosphate isomerases/epimerases. (277 aa) |
| | serA | COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa) |
| | tatD | Hydrolase, TatD family protein; COG0084 Mg-dependent DNase. (272 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (115 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | kbl | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (395 aa) |
| | rimO | SSU ribosomal protein s12p methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (441 aa) |
| | rsmB | Ribosomal RNA small subunit methyltransferase B; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (405 aa) |
| | SGRA_0702 | 23S rRNA (uracil-5-)-methyltransferase RumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (501 aa) |
| | SGRA_0706 | Organic hydroperoxide resistance protein; COG1764 Predicted redox protein, regulator of disulfide bond formation. (137 aa) |
| | SGRA_0713 | Thioesterase superfamily protein; COG1607 Acyl-CoA hydrolase. (172 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (241 aa) |
| | ltaA | COG2008 Threonine aldolase. (338 aa) |
| | SGRA_0799 | Transposase IS3/IS911 family protein; COG2801 Transposase and inactivated derivatives. (368 aa) |
| | SGRA_0857 | COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (255 aa) |
| | mraW | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (302 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa) |
| | rluF | Putative ribosomal RNA pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. (234 aa) |
| | engB | GTP-binding protein HSR1-related protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (202 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (596 aa) |
| | ppnK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (295 aa) |
| | SGRA_0940 | Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism. (145 aa) |
| | nrdA | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (803 aa) |
| | nrdB | Ribonucleoside-diphosphate reductase small chain; COG0208 Ribonucleotide reductase, beta subunit. (323 aa) |
| | htpG | ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity. (619 aa) |
| | katE | COG0753 Catalase; Belongs to the catalase family. (504 aa) |
| | SGRA_0982 | COG0686 Alanine dehydrogenase. (403 aa) |
| | SGRA_0987 | Integrase catalytic subunit; COG2801 Transposase and inactivated derivatives. (195 aa) |
| | SGRA_0990 | Transposase IS3/IS911 family protein; COG2963 Transposase and inactivated derivatives. (95 aa) |
| | SGRA_0994 | 2OG-Fe(II) oxygenase; COG3145 Alkylated DNA repair protein. (212 aa) |
| | speA | Orn/DAP/Arg decarboxylase 2; COG1166 Arginine decarboxylase (spermidine biosynthesis). (465 aa) |
| | truC | COG0564 Pseudouridylate synthases, 23S RNA-specific. (296 aa) |
| | pepD | Aminoacyl-histidine dipeptidase; COG2195 Di- and tripeptidases. (482 aa) |
| | fbp | COG0158 Fructose-1,6-bisphosphatase. (327 aa) |
| | gadB | COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (483 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (418 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (185 aa) |
| | SGRA_1113 | FeS assembly protein IscX; COG2975 Uncharacterized protein conserved in bacteria. (79 aa) |
| | SGRA_1114 | Cobalamin synthesis protein CobW; COG0523 Putative GTPases (G3E family). (332 aa) |
| | SGRA_1117 | FkbM family methyltransferase; COG0500 SAM-dependent methyltransferases. (299 aa) |
| | nusA | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. (438 aa) |
| | rimP | Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (162 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (417 aa) |
| | SGRA_1151 | Nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (399 aa) |
| | bioF | 8-amino-7-oxononanoate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. (376 aa) |
| | SGRA_1183 | Integrase catalytic subunit; COG2801 Transposase and inactivated derivatives. (165 aa) |
| | SGRA_1190 | Integrase catalytic region; COG2801 Transposase and inactivated derivatives. (251 aa) |
| | mvaD | COG3407 Mevalonate pyrophosphate decarboxylase. (347 aa) |
| | SGRA_1203 | Integrase catalytic subunit; COG2801 Transposase and inactivated derivatives. (195 aa) |
| | SGRA_1217 | Hypothetical protein. (288 aa) |
| | SGRA_1236 | COG2120 Uncharacterized proteins, LmbE homologs. (238 aa) |
| | SGRA_1244 | Hypothetical protein. (237 aa) |
| | SGRA_1250 | Type 4 fimbriae expression regulatory protein PilR; COG3283 Transcriptional regulator of aromatic amino acids metabolism. (300 aa) |
| | SGRA_1262 | Hypothetical protein; COG0500 SAM-dependent methyltransferases. (391 aa) |
| | SGRA_1323 | Integrase catalytic region; COG2801 Transposase and inactivated derivatives. (251 aa) |
| | SGRA_1339 | COG0566 rRNA methylases. (145 aa) |
| | SGRA_1340 | PfkB domain protein; COG0524 Sugar kinases, ribokinase family. (304 aa) |
| | SGRA_1374 | Hypothetical protein. (137 aa) |
| | SGRA_1381 | M22 family peptidase; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. (236 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (265 aa) |
| | SGRA_1401 | Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (427 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (623 aa) |
| | thiD | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (253 aa) |
| | thiG | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (256 aa) |
| | SGRA_1465 | Arsenate reductase; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (196 aa) |
| | hscB | Co-chaperone Hsc20; COG1076 DnaJ-domain-containing proteins 1. (176 aa) |
| | metF | COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (318 aa) |
| | SGRA_1551 | O-methyltransferase family 3; COG4122 Predicted O-methyltransferase. (214 aa) |
| | yhfA | COG1765 Predicted redox protein, regulator of disulfide bond formation. (139 aa) |
| | SGRA_1575 | Antibiotic biosynthesis monooxygenase domain protein. (98 aa) |
| | SGRA_1579 | Formyl transferase domain protein; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. (226 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (213 aa) |
| | SGRA_1649 | TPR repeat-containing protein; COG0457 FOG: TPR repeat. (469 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (589 aa) |
| | hemD | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (262 aa) |
| | rluD | Ribosomal large subunit pseudouridine synthase d; COG0564 Pseudouridylate synthases, 23S RNA-specific. (241 aa) |
| | cysQ | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (263 aa) |
| | SGRA_1702 | COG3228 Uncharacterized protein conserved in bacteria; Belongs to the MtfA family. (305 aa) |
| | sdaA-2 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (482 aa) |
| | aroE | COG0169 Shikimate 5-dehydrogenase. (273 aa) |
| | rfbB | COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (351 aa) |
| | ubiD | UbiD family decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. (610 aa) |
| | rplO | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (229 aa) |
| | rpmD | COG1841 Ribosomal protein L30/L7E. (59 aa) |
| | rpsE | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (171 aa) |
| | rpsH | Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (134 aa) |
| | rplE | Lsu ribosomal protein l5p; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (184 aa) |
| | rpsQ | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (88 aa) |
| | rpsC | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (254 aa) |
| | rplC | COG0087 Ribosomal protein L3. (218 aa) |
| | rpsG | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (157 aa) |
| | SGRA_1853 | COG3550 Uncharacterized protein related to capsule biosynthesis enzymes. (109 aa) |
| | SGRA_1859 | Thioesterase superfamily protein; COG1607 Acyl-CoA hydrolase. (128 aa) |
| | SGRA_1881 | RNA methyltransferase YjfH; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (250 aa) |
| | iscS | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (406 aa) |
| | iscU | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa) |
| | SGRA_1884 | Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. (108 aa) |
| | serA-2 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (340 aa) |
| | ksgA | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (264 aa) |
| | ald | COG0686 Alanine dehydrogenase. (407 aa) |
| | SGRA_1941 | Phosphodiesterase, MJ0936 family protein; COG0622 Predicted phosphoesterase. (173 aa) |
| | gidB | Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (210 aa) |
| | SGRA_1964 | NADPH-dependent FMN reductase; COG0431 Predicted flavoprotein. (180 aa) |
| | engA | Gtp-binding protein enga; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (433 aa) |
| | pfk | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa) |
| | SGRA_1978 | Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family. (237 aa) |
| | ptpS | COG0720 6-pyruvoyl-tetrahydropterin synthase. (138 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa) |
| | SGRA_2015 | Porphobilinogen deaminase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (221 aa) |
| | SGRA_2019 | UBA/THIF-type NAD/FAD binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. (383 aa) |
| | SGRA_2020 | Thiamine S protein; COG1977 Molybdopterin converting factor, small subunit. (93 aa) |
| | argD | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (405 aa) |
| | thrB | COG0083 Homoserine kinase. (303 aa) |
| | SGRA_2047 | Hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (365 aa) |
| | greA | Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (160 aa) |
| | dapD | COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (271 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (702 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (884 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (332 aa) |
| | yjfH | RNA methyltransferase, TrmH family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (239 aa) |
| | galE-2 | COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (347 aa) |
| | glyS1 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (519 aa) |
| | tadA | Cmp/dcmp deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa) |
| | SGRA_2247 | COG2120 Uncharacterized proteins, LmbE homologs. (237 aa) |
| | SGRA_2248 | COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (290 aa) |
| | SGRA_2251 | DNA mismatch repair protein MutS domain-containing protein; COG0249 Mismatch repair ATPase (MutS family). (589 aa) |
| | trpS | COG0180 Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (338 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (223 aa) |
| | SGRA_2279 | COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (150 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (618 aa) |
| | glgA | COG0297 Glycogen synthase. (271 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa) |
| | asnB | COG0367 Asparagine synthase (glutamine-hydrolyzing). (635 aa) |
| | yhbH | Ribosomal subunit interface protein; COG1544 Ribosome-associated protein Y (PSrp-1). (100 aa) |
| | nusG | NusG antitermination factor; Participates in transcription elongation, termination and antitermination. (180 aa) |
| | SGRA_2324 | Appr-1-p processing domain protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. (348 aa) |
| | SGRA_2329 | Putative deoxyribonucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (195 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (358 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (298 aa) |
| | SGRA_2370 | COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (485 aa) |
| | fdx-2 | COG0633 Ferredoxin. (108 aa) |
| | nudG | Pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. (132 aa) |
| | hflX | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (403 aa) |
| | SGRA_2457 | COG3228 Uncharacterized protein conserved in bacteria; Belongs to the MtfA family. (341 aa) |
| | rfbA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (289 aa) |
| | miaB | (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (483 aa) |
| | fabF | 3-oxoacyl-(acyl-carrier-protein) synthase ii; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (416 aa) |
| | upp | COG0035 Uracil phosphoribosyltransferase. (219 aa) |
| | rpsO | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (97 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (341 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa) |
| | SGRA_2594 | COG1956 GAF domain-containing protein. (163 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (298 aa) |
| | SGRA_2615 | CBS domain containing membrane protein; COG0517 FOG: CBS domain. (637 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa) |
| | SGRA_2626 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. (189 aa) |
| | metH | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1225 aa) |
| | SGRA_2652 | O-methyltransferase-like protein; COG4122 Predicted O-methyltransferase. (290 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa) |
| | spoU | tRNA/rRNA methyltransferase (SpoU); COG0566 rRNA methylases. (252 aa) |
| | SGRA_2715 | Hypothetical protein. (176 aa) |
| | SGRA_2731 | COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (254 aa) |
| | SGRA_2737 | RNA binding S1 domain protein; COG2183 Transcriptional accessory protein. (771 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (352 aa) |
| | SGRA_2758 | COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (253 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. (437 aa) |
| | clpB | ATP-dependent chaperone ClpB; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (878 aa) |
| | cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (161 aa) |
| | SGRA_2808 | Sua5/YciO/YrdC/YwlC family protein; COG0009 Putative translation factor (SUA5); Belongs to the SUA5 family. (207 aa) |
| | pdxJ | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (239 aa) |
| | SGRA_2861 | COG0621 2-methylthioadenine synthetase. (448 aa) |
| | ebsC | ybaK/ebsC protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (157 aa) |
| | hisC | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (389 aa) |
| | dcd | COG0717 Deoxycytidine deaminase. (178 aa) |
| | folP | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (284 aa) |
| | fabH-2 | COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III. (358 aa) |
| | SGRA_2969 | Putative SpoU rRNA methylase family protein; COG0566 rRNA methylases. (179 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (296 aa) |
| | SGRA_3023 | VWA containing CoxE family protein. (381 aa) |
| | SGRA_3027 | Regulatory protein (nitrile hydratase activator like); COG0523 Putative GTPases (G3E family). (401 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) |
| | SGRA_3051 | Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (424 aa) |
| | rlmI | COG1092 Predicted SAM-dependent methyltransferases. (408 aa) |
| | ybaZ | methylated-DNA-[protein]-cysteine S-methyltransferase; COG0350 Methylated DNA-protein cysteine methyltransferase. (104 aa) |
| | rfbA-2 | Nucleotidyl transferase; COG1209 dTDP-glucose pyrophosphorylase. (331 aa) |
| | rluD-2 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (245 aa) |
| | folA | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (175 aa) |
| | folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (174 aa) |
| | SGRA_3175 | Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism. (143 aa) |
| | iscS-2 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (376 aa) |
| | cheB | Protein-glutamate methylesterase, two-component response regulator, chemotaxis; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (349 aa) |
| | cheR | MCP methyltransferase, CheR-type; COG1352 Methylase of chemotaxis methyl-accepting proteins. (280 aa) |
| | SGRA_3227 | MCP methyltransferase, CheR-type; COG1352 Methylase of chemotaxis methyl-accepting proteins. (260 aa) |
| | pncB | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (484 aa) |
| | SGRA_3255 | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family. (240 aa) |
| | pncA | Nicotinamidase; COG1335 Amidases related to nicotinamidase. (207 aa) |
| | SGRA_3266 | SUA5/yciO/yrdC domain protein; COG0009 Putative translation factor (SUA5); Belongs to the SUA5 family. (187 aa) |
| | clpX | Sigma 54 interacting domain protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (419 aa) |
| | msrA | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (182 aa) |
| | SGRA_3347 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (221 aa) |
| | folE | COG0302 GTP cyclohydrolase I. (231 aa) |
| | ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (710 aa) |
| | nadB | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (534 aa) |
| | hslR | COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog). (139 aa) |
| | manA | Bifunctional phosphoglucose/phosphomannose isomerase; COG0166 Glucose-6-phosphate isomerase. (330 aa) |
| | rluD-3 | Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (345 aa) |
| | SGRA_3392 | COG1832 Predicted CoA-binding protein. (121 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (342 aa) |
| | lysC | COG0527 Aspartokinases; Belongs to the aspartokinase family. (424 aa) |
| | hsdR-2 | COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases. (1132 aa) |
| | SGRA_3463 | Transposase IS3/IS911 family protein; COG2963 Transposase and inactivated derivatives. (95 aa) |
| | SGRA_3468 | COG2801 Transposase and inactivated derivatives. (253 aa) |
| | SGRA_3478 | COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). (327 aa) |
| | SGRA_3506 | Integrase catalytic region; COG2801 Transposase and inactivated derivatives. (156 aa) |
| | SGRA_3526 | COG0262 Dihydrofolate reductase. (176 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (927 aa) |
| | amn | AMP nucleosidase; COG0775 Nucleoside phosphorylase. (257 aa) |
| | SGRA_3602 | Integrase catalytic subunit; COG2801 Transposase and inactivated derivatives. (241 aa) |
| | SGRA_3603 | Transposase IS3/IS911 family protein; COG2963 Transposase and inactivated derivatives. (95 aa) |
| | SGRA_3648 | Hypothetical protein; COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase. (271 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (174 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (378 aa) |
| | SGRA_3658 | COG3022 Uncharacterized protein conserved in bacteria; Belongs to the UPF0246 family. (250 aa) |
| | SGRA_3716 | Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (181 aa) |
| | SGRA_3748 | Hypothetical protein; COG3150 Predicted esterase. (161 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (238 aa) |
| | tdk | COG1435 Thymidine kinase. (184 aa) |
| | phnA | Alkylphosphonate utilization operon protein phna; COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism. (79 aa) |
| | cmk | COG0283 Cytidylate kinase. (237 aa) |
| | sfcA | Malate dehydrogenase; COG0281 Malic enzyme. (403 aa) |
| | SGRA_3831 | HI0933 family protein; COG2081 Predicted flavoproteins. (405 aa) |
| | SGRA_3832 | Hypothetical protein. (378 aa) |
| | SGRA_3834 | WD40 repeat, subgroup; COG2319 FOG: WD40 repeat. (292 aa) |
| | SGRA_3842 | Nucleotidyl transferase; COG1209 dTDP-glucose pyrophosphorylase. (328 aa) |
| | katE-2 | COG0753 Catalase. (576 aa) |
| | dapB | COG0289 Dihydrodipicolinate reductase; Belongs to the DapB family. (242 aa) |
| | SGRA_3883 | NAD-dependent epimerase/dehydratase; COG0451 Nucleoside-diphosphate-sugar epimerases. (341 aa) |
| | SGRA_3885 | Hypothetical protein; COG1561 Uncharacterized stress-induced protein. (287 aa) |
| | bioA | COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (432 aa) |
| | SGRA_3908 | COG0542 ATPases with chaperone activity, ATP-binding subunit. (1098 aa) |
| | SGRA_3937 | COG0542 ATPases with chaperone activity, ATP-binding subunit. (1098 aa) |
| | wbpO | Nucleotide sugar dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (430 aa) |
| | rocD | COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa) |
| | SGRA_4031 | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (363 aa) |
| | mnmA | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (391 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (672 aa) |
| | asnB-2 | COG0367 Asparagine synthase (glutamine-hydrolyzing). (622 aa) |
| | udp | Phosphorylase family protein; COG2820 Uridine phosphorylase. (288 aa) |
| | SGRA_4105 | COG2801 Transposase and inactivated derivatives. (253 aa) |
| | SGRA_4109 | Transposase IS3/IS911 family protein; COG2963 Transposase and inactivated derivatives. (95 aa) |
| | ptpS-2 | COG0720 6-pyruvoyl-tetrahydropterin synthase. (138 aa) |
| | SGRA_4159 | Integrase catalytic region; COG2801 Transposase and inactivated derivatives. (251 aa) |
| | argS | COG0018 Arginyl-tRNA synthetase. (644 aa) |
| | SGRA_4169 | NAD-dependent epimerase/dehydratase; COG0451 Nucleoside-diphosphate-sugar epimerases. (350 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (376 aa) |
| | SGRA_4190 | COG1607 Acyl-CoA hydrolase. (163 aa) |
| | SGRA_4226 | Metallophosphoesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (319 aa) |
