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| | SGRA_4226 | Metallophosphoesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (319 aa) |
| | SGRA_0034 | Putative metallopeptidase, M16 family protein. (336 aa) |
| | mdaB | NAD(P)H dehydrogenase (quinone); COG2249 Putative NADPH-quinone reductase (modulator of drug activity B). (197 aa) |
| | SGRA_0240 | Patatin. (825 aa) |
| | pepP | COG0006 Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family. (466 aa) |
| | SGRA_0279 | Band 7 protein; COG0330 Membrane protease subunits, stomatin/prohibitin homologs. (314 aa) |
| | SGRA_0288 | Hypothetical protein. (1336 aa) |
| | plsB | COG2937 Glycerol-3-phosphate O-acyltransferase. (579 aa) |
| | SGRA_0460 | Vitamin K-dependent gamma-carboxylase. (434 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (340 aa) |
| | SGRA_0541 | COG3597 Uncharacterized protein/domain associated with GTPases. (242 aa) |
| | SGRA_0564 | Riboflavin biosynthesis protein RibF; COG0196 FAD synthase; Belongs to the ribF family. (315 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (304 aa) |
| | SGRA_0593 | COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family. (354 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (192 aa) |
| | prpE | prpE protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (627 aa) |
| | SGRA_0713 | Thioesterase superfamily protein; COG1607 Acyl-CoA hydrolase. (172 aa) |
| | SGRA_0771 | Hypothetical protein. (617 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (227 aa) |
| | SGRA_0820 | COG0724 RNA-binding proteins (RRM domain). (122 aa) |
| | katE | COG0753 Catalase; Belongs to the catalase family. (504 aa) |
| | SGRA_0994 | 2OG-Fe(II) oxygenase; COG3145 Alkylated DNA repair protein. (212 aa) |
| | speA | Orn/DAP/Arg decarboxylase 2; COG1166 Arginine decarboxylase (spermidine biosynthesis). (465 aa) |
| | SGRA_1023 | RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (554 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (191 aa) |
| | SGRA_1077 | Hypothetical protein; COG1090 Predicted nucleoside-diphosphate sugar epimerase. (307 aa) |
| | ruvX | Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (171 aa) |
| | SGRA_1103 | Vitamin k-dependent gamma-carboxylase. (440 aa) |
| | SGRA_1115 | M20/M25/M40 family peptidase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (462 aa) |
| | crt | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa) |
| | SGRA_1217 | Hypothetical protein. (288 aa) |
| | moxR | COG0714 MoxR-like ATPases. (331 aa) |
| | hipO | N-acyl-L-amino acid amidohydrolase; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (398 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (335 aa) |
| | SGRA_1374 | Hypothetical protein. (137 aa) |
| | speB | Arginase/agmatinase/formiminoglutamase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. (342 aa) |
| | SGRA_1459 | COG0785 Cytochrome c biogenesis protein. (234 aa) |
| | SGRA_1463 | COG0526 Thiol-disulfide isomerase and thioredoxins. (78 aa) |
| | SGRA_1541 | COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (241 aa) |
| | SGRA_1563 | Short-chain dehydrogenase/reductase sdr; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (232 aa) |
| | gldK | Gliding motility protein GldK. (421 aa) |
| | rpsB | COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (241 aa) |
| | nadC | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (285 aa) |
| | lpxA | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (261 aa) |
| | moxR-2 | ATPase associated with various cellular activities AAA_3; COG0714 MoxR-like ATPases. (320 aa) |
| | fadD | COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (607 aa) |
| | phnP | COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I. (254 aa) |
| | rfbB-2 | dTDP-glucose 4,6-dehydratase, NAD-dependent epimerase/dehydratase-related protein; COG0451 Nucleoside-diphosphate-sugar epimerases. (310 aa) |
| | SGRA_1751 | Hypothetical protein. (256 aa) |
| | SGRA_1813 | AAA ATPase central domain protein; COG0464 ATPases of the AAA+ class. (462 aa) |
| | rpsD | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (204 aa) |
| | rpsM | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (125 aa) |
| | rplP | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (140 aa) |
| | rpsL | Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (128 aa) |
| | SGRA_1859 | Thioesterase superfamily protein; COG1607 Acyl-CoA hydrolase. (128 aa) |
| | motB | OmpA/MotB domain protein; COG1360 Flagellar motor protein. (347 aa) |
| | iscS | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (406 aa) |
| | galE | NAD dependent epimerase; COG0451 Nucleoside-diphosphate-sugar epimerases. (330 aa) |
| | SGRA_1936 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (665 aa) |
| | SGRA_1937 | COG0506 Proline dehydrogenase. (362 aa) |
| | elaA | GCN5-like N-acetyltransferase; COG2153 Predicted acyltransferase. (153 aa) |
| | SGRA_1965 | Beta-lactamase domain protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; Belongs to the UPF0173 family. (232 aa) |
| | SGRA_1997 | COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (636 aa) |
| | ptpS | COG0720 6-pyruvoyl-tetrahydropterin synthase. (138 aa) |
| | SGRA_2010 | Fumarylacetoacetate (FAA) hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (204 aa) |
| | arsA | Arsenite-activated ATPase (arsA) subfamily protein; COG0003 Oxyanion-translocating ATPase. (384 aa) |
| | SGRA_2036 | Cytochrome oxidase assembly; COG1612 Uncharacterized protein required for cytochrome oxidase assembly. (383 aa) |
| | tktA | COG3959 Transketolase, N-terminal subunit. (281 aa) |
| | SGRA_2042 | Peptidase m48 ste24p; COG4783 Putative Zn-dependent protease, contains TPR repeats. (265 aa) |
| | SGRA_2044 | Arginase. (349 aa) |
| | SGRA_2068 | Metal dependent phosphohydrolase; COG1078 HD superfamily phosphohydrolases. (406 aa) |
| | ybeY | Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (145 aa) |
| | SGRA_2223 | COG1960 Acyl-CoA dehydrogenases. (598 aa) |
| | hit | HIT family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. (133 aa) |
| | SGRA_2231 | Peptidase M28; COG2234 Predicted aminopeptidases. (332 aa) |
| | tadA | Cmp/dcmp deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa) |
| | SGRA_2249 | COG1257 Hydroxymethylglutaryl-CoA reductase. (515 aa) |
| | SGRA_2262 | Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG1225 Peroxiredoxin. (203 aa) |
| | SGRA_2281 | Putative thiol-disulfide oxidoreductase DCC; COG3011 Uncharacterized protein conserved in bacteria. (135 aa) |
| | rplA | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (230 aa) |
| | pssA | CDP-diacylglycerol-serine O-phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (248 aa) |
| | SGRA_2327 | Transporter, EamA; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. (316 aa) |
| | ilvE | COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (362 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (466 aa) |
| | SGRA_2392 | COG3000 Sterol desaturase. (401 aa) |
| | fdx-2 | COG0633 Ferredoxin. (108 aa) |
| | SGRA_2394 | Bacterioferritin comigratory protein; COG1225 Peroxiredoxin. (157 aa) |
| | SGRA_2416 | Transcriptional regulator, XRE family; COG1813 Predicted transcription factor, homolog of eukaryotic MBF1. (105 aa) |
| | SGRA_2419 | COG3255 Putative sterol carrier protein. (105 aa) |
| | serC | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (355 aa) |
| | pyk | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa) |
| | SGRA_2540 | Hypothetical protein. (121 aa) |
| | pdhB | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa) |
| | SGRA_2576 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (361 aa) |
| | SGRA_2608 | Sigma factor regulation protein; COG2203 FOG: GAF domain. (432 aa) |
| | SGRA_2611 | COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family. (538 aa) |
| | SGRA_2615 | CBS domain containing membrane protein; COG0517 FOG: CBS domain. (637 aa) |
| | folK | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (162 aa) |
| | SGRA_2628 | COG1428 Deoxynucleoside kinases. (219 aa) |
| | cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (161 aa) |
| | pepC | Peptidase C1B bleomycin hydrolase; COG3579 Aminopeptidase C; Belongs to the peptidase C1 family. (403 aa) |
| | moxR-3 | MoxR-like ATPase, regulator; COG0714 MoxR-like ATPases. (343 aa) |
| | SGRA_2877 | Vitamin k-dependent gamma-carboxylase-like protein. (428 aa) |
| | SGRA_2909 | Peptidase, M28D family protein; COG2234 Predicted aminopeptidases. (465 aa) |
| | hmgL | hydroxymethylglutaryl-CoA lyase; COG0119 Isopropylmalate/homocitrate/citramalate synthases. (276 aa) |
| | ychF | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (367 aa) |
| | gcdH | COG1960 Acyl-CoA dehydrogenases. (405 aa) |
| | SGRA_3003 | COG1960 Acyl-CoA dehydrogenases. (599 aa) |
| | gldJ | Gliding motility protein GldJ. (511 aa) |
| | ybaZ | methylated-DNA-[protein]-cysteine S-methyltransferase; COG0350 Methylated DNA-protein cysteine methyltransferase. (104 aa) |
| | SGRA_3095 | Riboflavin biosynthesis protein ribd; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (348 aa) |
| | SGRA_3100 | MoxR-like protein ATPase-like protein; COG0714 MoxR-like ATPases. (372 aa) |
| | fixB | COG2025 Electron transfer flavoprotein, alpha subunit. (319 aa) |
| | SGRA_3127 | Nudix hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (218 aa) |
| | SGRA_3129 | COG1231 Monoamine oxidase. (447 aa) |
| | SGRA_3137 | ATPase; COG0714 MoxR-like ATPases. (366 aa) |
| | SGRA_3138 | Hypothetical protein. (509 aa) |
| | SGRA_3156 | Hypothetical protein. (473 aa) |
| | iscS-2 | COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (376 aa) |
| | rsbU | COG2208 Serine phosphatase RsbU, regulator of sigma subunit. (542 aa) |
| | kptA | Phosphate acetyltransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (186 aa) |
| | sbcD | Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (405 aa) |
| | SGRA_3293 | ATPase; COG0017 Aspartyl/asparaginyl-tRNA synthetases. (1654 aa) |
| | SGRA_3304 | Hypothetical protein; COG1077 Actin-like ATPase involved in cell morphogenesis. (1163 aa) |
| | glcD | (S)-2-hydroxy-acid oxidase; COG0277 FAD/FMN-containing dehydrogenases. (468 aa) |
| | SGRA_3391 | Monooxygenase FAD-binding protein; COG0644 Dehydrogenases (flavoproteins). (388 aa) |
| | SGRA_3396 | 5 nucleotidase deoxy cytosolic type C; COG4502 Uncharacterized protein conserved in bacteria. (149 aa) |
| | SGRA_3436 | hydroxymethylglutaryl-CoA reductase, degradative; COG1257 Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (460 aa) |
| | idi | Isopentenyl pyrophosphate isomerase; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. (341 aa) |
| | acs | Acetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (633 aa) |
| | SGRA_3458 | COG1741 Pirin-related protein; Belongs to the pirin family. (287 aa) |
| | SGRA_3483 | Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG1225 Peroxiredoxin. (208 aa) |
| | SGRA_3527 | Hypothetical protein. (474 aa) |
| | SGRA_3529 | COG1960 Acyl-CoA dehydrogenases. (388 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (330 aa) |
| | SGRA_3733 | COG1428 Deoxynucleoside kinases. (210 aa) |
| | aspB | Aminotransferase class I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (399 aa) |
| | SGRA_3811 | Peptidase S9B dipeptidylpeptidase IV domain protein; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases. (714 aa) |
| | guaC | Guanosine 5'-monophosphate oxidoreductase; COG0516 IMP dehydrogenase/GMP reductase. (340 aa) |
| | SGRA_3848 | Cation diffusion facilitator family transporter; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (334 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (191 aa) |
| | katE-2 | COG0753 Catalase. (576 aa) |
| | SGRA_3883 | NAD-dependent epimerase/dehydratase; COG0451 Nucleoside-diphosphate-sugar epimerases. (341 aa) |
| | SGRA_3939 | COG2020 Putative protein-S-isoprenylcysteine methyltransferase. (248 aa) |
| | SGRA_3958 | Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG1225 Peroxiredoxin. (152 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (264 aa) |
| | rocF | Arginase/agmatinase/formiminoglutamase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. (326 aa) |
| | SGRA_4026 | Hypothetical protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold. (262 aa) |
| | SGRA_4028 | COG1960 Acyl-CoA dehydrogenases. (613 aa) |
| | ptpS-2 | COG0720 6-pyruvoyl-tetrahydropterin synthase. (138 aa) |
| | hemB | COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (333 aa) |
| | ycaJ | Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase. (424 aa) |
| | SGRA_4153 | Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG0526 Thiol-disulfide isomerase and thioredoxins. (180 aa) |
| | SGRA_4169 | NAD-dependent epimerase/dehydratase; COG0451 Nucleoside-diphosphate-sugar epimerases. (350 aa) |
| | SGRA_4190 | COG1607 Acyl-CoA hydrolase. (163 aa) |
| | SGRA_0017 | COG1960 Acyl-CoA dehydrogenases. (383 aa) |
| | SGRA_0030 | Peptidase S9B dipeptidylpeptidase IV domain protein; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases. (718 aa) |
