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SGRA_4226 SGRA_4226 SGRA_4026 SGRA_4026 SGRA_3527 SGRA_3527 acs acs iscS-2 iscS-2 SGRA_3138 SGRA_3138 fixB fixB gldJ gldJ cdd cdd pdhB pdhB SGRA_2540 SGRA_2540 fdx-2 fdx-2 ilvE ilvE SGRA_1965 SGRA_1965 SGRA_1937 SGRA_1937 iscS iscS SGRA_1859 SGRA_1859 SGRA_1813 SGRA_1813 rpsB rpsB gldK gldK SGRA_1463 SGRA_1463 hipO hipO crt crt SGRA_1115 SGRA_1115 SGRA_0994 SGRA_0994 SGRA_0820 SGRA_0820 SGRA_0713 SGRA_0713 prpE prpE SGRA_0034 SGRA_0034 SGRA_4190 SGRA_4190
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGRA_4226Metallophosphoesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (319 aa)
SGRA_4026Hypothetical protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold. (262 aa)
SGRA_3527Hypothetical protein. (474 aa)
acsAcetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (633 aa)
iscS-2COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (376 aa)
SGRA_3138Hypothetical protein. (509 aa)
fixBCOG2025 Electron transfer flavoprotein, alpha subunit. (319 aa)
gldJGliding motility protein GldJ. (511 aa)
cddCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (161 aa)
pdhBTransketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa)
SGRA_2540Hypothetical protein. (121 aa)
fdx-2COG0633 Ferredoxin. (108 aa)
ilvECOG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (362 aa)
SGRA_1965Beta-lactamase domain protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; Belongs to the UPF0173 family. (232 aa)
SGRA_1937COG0506 Proline dehydrogenase. (362 aa)
iscSCysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (406 aa)
SGRA_1859Thioesterase superfamily protein; COG1607 Acyl-CoA hydrolase. (128 aa)
SGRA_1813AAA ATPase central domain protein; COG0464 ATPases of the AAA+ class. (462 aa)
rpsBCOG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (241 aa)
gldKGliding motility protein GldK. (421 aa)
SGRA_1463COG0526 Thiol-disulfide isomerase and thioredoxins. (78 aa)
hipON-acyl-L-amino acid amidohydrolase; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (398 aa)
crtCOG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
SGRA_1115M20/M25/M40 family peptidase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (462 aa)
SGRA_09942OG-Fe(II) oxygenase; COG3145 Alkylated DNA repair protein. (212 aa)
SGRA_0820COG0724 RNA-binding proteins (RRM domain). (122 aa)
SGRA_0713Thioesterase superfamily protein; COG1607 Acyl-CoA hydrolase. (172 aa)
prpEprpE protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (627 aa)
SGRA_0034Putative metallopeptidase, M16 family protein. (336 aa)
SGRA_4190COG1607 Acyl-CoA hydrolase. (163 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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