STRINGSTRING
moxR-2 moxR-2 rho rho mfd mfd phoH phoH SGRA_1715 SGRA_1715 spoVK spoVK SGRA_1729 SGRA_1729 SGRA_1742 SGRA_1742 uvrB uvrB SGRA_1813 SGRA_1813 fusA fusA secA secA prfC prfC icmF icmF trmE trmE lptB lptB feoB feoB engA engA atpD atpD uvrD uvrD coaE coaE recA recA arsA arsA holB holB recG recG typA typA mutS mutS uvrA uvrA gldA gldA SGRA_2216 SGRA_2216 SGRA_2251 SGRA_2251 SGRA_2287 SGRA_2287 tufA tufA atpA atpA ftsY ftsY uvrA-2 uvrA-2 lepA lepA hflX hflX SGRA_2500 SGRA_2500 ruvB ruvB SGRA_2572 SGRA_2572 mutS2 mutS2 era era SGRA_2628 SGRA_2628 argK argK miaA miaA rsgA rsgA dnaB dnaB clpB clpB moxR-3 moxR-3 SGRA_2901 SGRA_2901 deaD deaD ychF ychF SGRA_2984 SGRA_2984 ftsK ftsK SGRA_3027 SGRA_3027 SGRA_3037 SGRA_3037 SGRA_3059 SGRA_3059 SGRA_3086 SGRA_3086 SGRA_3089 SGRA_3089 parA parA SGRA_3100 SGRA_3100 SGRA_3137 SGRA_3137 SGRA_3185 SGRA_3185 recB recB SGRA_3257 SGRA_3257 holA holA SGRA_3293 SGRA_3293 ffh ffh clpX clpX SGRA_3346 SGRA_3346 SGRA_3397 SGRA_3397 SGRA_3404 SGRA_3404 recN recN SGRA_1633 SGRA_1633 SGRA_1638 SGRA_1638 bioD bioD adk adk pilB pilB purA purA SGRA_0724 SGRA_0724 priA priA SGRA_0757 SGRA_0757 SGRA_0764 SGRA_0764 SGRA_0814 SGRA_0814 SGRA_0849 SGRA_0849 engB engB SGRA_0947 SGRA_0947 recQ recQ mcrB mcrB udk udk SGRA_1114 SGRA_1114 infB infB SGRA_1132 SGRA_1132 SGRA_1218 SGRA_1218 moxR moxR SGRA_1250 SGRA_1250 SGRA_1255 SGRA_1255 dnaX dnaX SGRA_1285 SGRA_1285 SGRA_1303 SGRA_1303 ftsH ftsH SGRA_1364 SGRA_1364 SGRA_1384 SGRA_1384 obgE obgE hsdR-2 hsdR-2 aroK aroK SGRA_3539 SGRA_3539 sms sms SGRA_3570 SGRA_3570 SGRA_3606 SGRA_3606 recQ-3 recQ-3 comM comM SGRA_3680 SGRA_3680 recD recD SGRA_3722 SGRA_3722 SGRA_3733 SGRA_3733 macB macB SGRA_3736 SGRA_3736 tdk tdk cmk cmk SGRA_3813 SGRA_3813 clpC clpC SGRA_3849 SGRA_3849 SGRA_3869 SGRA_3869 SGRA_3877 SGRA_3877 SGRA_3880 SGRA_3880 gmk gmk SGRA_3894 SGRA_3894 hsdR-3 hsdR-3 SGRA_3908 SGRA_3908 SGRA_3937 SGRA_3937 smc smc SGRA_4057 SGRA_4057 SGRA_4069 SGRA_4069 SGRA_4128 SGRA_4128 SGRA_4131 SGRA_4131 ycaJ ycaJ uvrD-2 uvrD-2 recF recF SGRA_0414 SGRA_0414 SGRA_0403 SGRA_0403 SGRA_0401 SGRA_0401 sbcC sbcC mrp mrp SGRA_0322 SGRA_0322 lolD lolD SGRA_0306 SGRA_0306 hsdR hsdR SGRA_0288 SGRA_0288 SGRA_0244 SGRA_0244 SGRA_0221 SGRA_0221 SGRA_0212 SGRA_0212 SGRA_0195 SGRA_0195 SGRA_0181 SGRA_0181 pyrG pyrG lon lon SGRA_0043 SGRA_0043 SGRA_0036 SGRA_0036 dnaA dnaA recQ-2 recQ-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
moxR-2ATPase associated with various cellular activities AAA_3; COG0714 MoxR-like ATPases. (320 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (589 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1122 aa)
phoHPhoh family protein; COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. (339 aa)
SGRA_1715ATP-binding protein; COG1106 Predicted ATPases. (434 aa)
spoVKStage V sporulation protein K; COG0464 ATPases of the AAA+ class. (875 aa)
SGRA_1729Cobyrinic acid ac-diamide synthase; COG1192 ATPases involved in chromosome partitioning. (280 aa)
SGRA_1742ABC transporter related protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. (605 aa)
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (680 aa)
SGRA_1813AAA ATPase central domain protein; COG0464 ATPases of the AAA+ class. (462 aa)
fusAElongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (710 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (1110 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (526 aa)
icmFmethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1119 aa)
trmEtRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (455 aa)
lptBABC transporter related protein; COG1137 ABC-type (unclassified) transport system, ATPase component. (246 aa)
feoBFerrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (648 aa)
engAGtp-binding protein enga; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (433 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (502 aa)
uvrDCOG0210 Superfamily I DNA and RNA helicases; Belongs to the helicase family. UvrD subfamily. (1069 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa)
recArecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (372 aa)
arsAArsenite-activated ATPase (arsA) subfamily protein; COG0003 Oxyanion-translocating ATPase. (384 aa)
holBCOG2812 DNA polymerase III, gamma/tau subunits. (385 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (702 aa)
typAGTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response. (607 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (884 aa)
uvrAExcinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (943 aa)
gldAGliding motility protein GldA; COG1131 ABC-type multidrug transport system, ATPase component. (363 aa)
SGRA_2216ABC transporter-related protein; COG1122 ABC-type cobalt transport system, ATPase component. (222 aa)
SGRA_2251DNA mismatch repair protein MutS domain-containing protein; COG0249 Mismatch repair ATPase (MutS family). (589 aa)
SGRA_2287ABC transporter, ATP-binding protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily. (570 aa)
tufATranslation elongation factor 1a (ef-1a/ef-tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (395 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (534 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (322 aa)
uvrA-2UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (930 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (596 aa)
hflXGTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (403 aa)
SGRA_2500Sigma54 specific transcriptional regulator, Fis family protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (433 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (341 aa)
SGRA_2572SMC domain protein; COG4637 Predicted ATPase. (454 aa)
mutS2MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (800 aa)
eraGTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (299 aa)
SGRA_2628COG1428 Deoxynucleoside kinases. (219 aa)
argKArginine/ornithine transport system ATPase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family. (360 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa)
rsgAGTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (312 aa)
dnaBPrimary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (510 aa)
clpBATP-dependent chaperone ClpB; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (878 aa)
moxR-3MoxR-like ATPase, regulator; COG0714 MoxR-like ATPases. (343 aa)
SGRA_2901Hypothetical protein; COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA. (678 aa)
deaDDEAD/DEAH box helicase domain protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. (474 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (367 aa)
SGRA_2984AAA ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (399 aa)
ftsKCOG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins. (850 aa)
SGRA_3027Regulatory protein (nitrile hydratase activator like); COG0523 Putative GTPases (G3E family). (401 aa)
SGRA_3037SMC domain protein; COG1122 ABC-type cobalt transport system, ATPase component. (620 aa)
SGRA_3059Iron ABC transporter ATP-binding protein; COG4559 ABC-type hemin transport system, ATPase component. (267 aa)
SGRA_3086COG0464 ATPases of the AAA+ class. (868 aa)
SGRA_3089ABC transporter related protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component. (236 aa)
parACOG1192 ATPases involved in chromosome partitioning. (258 aa)
SGRA_3100MoxR-like protein ATPase-like protein; COG0714 MoxR-like ATPases. (372 aa)
SGRA_3137ATPase; COG0714 MoxR-like ATPases. (366 aa)
SGRA_3185ABC transporter related protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. (600 aa)
recBUvrD/REP helicase; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains). (1091 aa)
SGRA_3257Hypothetical protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. (371 aa)
holACOG1466 DNA polymerase III, delta subunit. (356 aa)
SGRA_3293ATPase; COG0017 Aspartyl/asparaginyl-tRNA synthetases. (1654 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (447 aa)
clpXSigma 54 interacting domain protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (419 aa)
SGRA_3346HlyB/MsbA family ABC transporter; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain. (580 aa)
SGRA_3397ABC transporter related protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. (597 aa)
SGRA_3404ATPase-like protein; COG4637 Predicted ATPase. (354 aa)
recNDNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (552 aa)
SGRA_1633AAA ATPase; COG1112 Superfamily I DNA and RNA helicases and helicase subunits. (637 aa)
SGRA_1638ABC transporter related protein; COG1131 ABC-type multidrug transport system, ATPase component. (210 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (213 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (192 aa)
pilBCOG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. (478 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (422 aa)
SGRA_0724ABC transporter ATP-binding protein; COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component. (255 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (839 aa)
SGRA_0757COG0488 ATPase components of ABC transporters with duplicated ATPase domains. (448 aa)
SGRA_0764Putative two component, sigma54 specific, transcriptional regulator, Fis family protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (421 aa)
SGRA_0814ATPase-like protein; COG1106 Predicted ATPases. (1555 aa)
SGRA_0849COG1112 Superfamily I DNA and RNA helicases and helicase subunits. (1342 aa)
engBGTP-binding protein HSR1-related protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (202 aa)
SGRA_0947ABC transporter, ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. (240 aa)
recQATP-dependent DNA helicase, RecQ family protein; COG0514 Superfamily II DNA helicase. (2930 aa)
mcrBATPase associated with various cellular activities AAA_5; COG1401 GTPase subunit of restriction endonuclease. (549 aa)
udkCOG0572 Uridine kinase. (209 aa)
SGRA_1114Cobalamin synthesis protein CobW; COG0523 Putative GTPases (G3E family). (332 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (1002 aa)
SGRA_1132Two component, sigma54 specific, Fis family transcriptional regulator; COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain. (534 aa)
SGRA_1218ABC transporter related protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component. (315 aa)
moxRCOG0714 MoxR-like ATPases. (331 aa)
SGRA_1250Type 4 fimbriae expression regulatory protein PilR; COG3283 Transcriptional regulator of aromatic amino acids metabolism. (300 aa)
SGRA_1255Type 4 fimbriae expression regulatory protein PilR; COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain. (608 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (593 aa)
SGRA_1285Hypothetical protein; COG0802 Predicted ATPase or kinase. (143 aa)
SGRA_1303WD-40 repeat-containing protein; COG1117 ABC-type phosphate transport system, ATPase component. (1119 aa)
ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (675 aa)
SGRA_1364DNA helicase; COG1112 Superfamily I DNA and RNA helicases and helicase subunits. (1127 aa)
SGRA_1384COG0488 ATPase components of ABC transporters with duplicated ATPase domains. (646 aa)
obgEGTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (335 aa)
hsdR-2COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases. (1132 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (174 aa)
SGRA_3539Putative ATP binding protein; COG1129 ABC-type sugar transport system, ATPase component. (500 aa)
smsDNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (464 aa)
SGRA_3570ABC-type transporter ATP-binding protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains. (622 aa)
SGRA_3606Hypothetical protein. (429 aa)
recQ-3ATP-dependent DNA helicase, RecQ family protein; COG0514 Superfamily II DNA helicase. (654 aa)
comMMg chelatase, subunit chli; COG0606 Predicted ATPase with chaperone activity. (518 aa)
SGRA_3680WD-40 repeat-containing protein; COG1672 Predicted ATPase (AAA+ superfamily). (355 aa)
recDPutative exodeoxyribonuclease V; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. (762 aa)
SGRA_3722ABC transporter related protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. (597 aa)
SGRA_3733COG1428 Deoxynucleoside kinases. (210 aa)
macBABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (250 aa)
SGRA_3736Hypothetical protein; COG0210 Superfamily I DNA and RNA helicases. (1481 aa)
tdkCOG1435 Thymidine kinase. (184 aa)
cmkCOG0283 Cytidylate kinase. (237 aa)
SGRA_3813Hypothetical protein; COG1100 GTPase SAR1 and related small G proteins. (151 aa)
clpCATPase AAA-2 domain protein; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (847 aa)
SGRA_3849COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. (460 aa)
SGRA_3869SMC domain-containing protein; COG3950 Predicted ATP-binding protein involved in virulence. (433 aa)
SGRA_3877COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. (414 aa)
SGRA_3880Hypothetical protein; COG1106 Predicted ATPases. (422 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (206 aa)
SGRA_3894SMC domain-containing protein; COG3950 Predicted ATP-binding protein involved in virulence. (441 aa)
hsdR-3Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1070 aa)
SGRA_3908COG0542 ATPases with chaperone activity, ATP-binding subunit. (1098 aa)
SGRA_3937COG0542 ATPases with chaperone activity, ATP-binding subunit. (1098 aa)
smcChromosome segregation protein smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1173 aa)
SGRA_4057COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component. (428 aa)
SGRA_4069ATP/GTP-binding protein; COG3593 Predicted ATP-dependent endonuclease of the OLD family. (761 aa)
SGRA_4128COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases. (1036 aa)
SGRA_4131ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (751 aa)
ycaJRecombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase. (424 aa)
uvrD-2COG0210 Superfamily I DNA and RNA helicases. (759 aa)
recFDNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (372 aa)
SGRA_0414COG0542 ATPases with chaperone activity, ATP-binding subunit. (753 aa)
SGRA_0403AAA ATPase; COG3950 Predicted ATP-binding protein involved in virulence. (440 aa)
SGRA_0401SMC domain protein; COG3950 Predicted ATP-binding protein involved in virulence. (532 aa)
sbcCSMC domain protein; COG0419 ATPase involved in DNA repair. (1222 aa)
mrpATP-binding protein, Mrp/Nbp35 family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (364 aa)
SGRA_0322Adenylate kinase. (187 aa)
lolDABC transporter related protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (220 aa)
SGRA_0306TPR repeat-containing protein; COG1401 GTPase subunit of restriction endonuclease. (825 aa)
hsdRType I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification. (936 aa)
SGRA_0288Hypothetical protein. (1336 aa)
SGRA_0244Hypothetical protein; COG1106 Predicted ATPases. (399 aa)
SGRA_0221ABC transporter related protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components. (212 aa)
SGRA_0212Hypothetical protein; COG4637 Predicted ATPase. (946 aa)
SGRA_0195ABC transporter related protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component. (233 aa)
SGRA_0181AAA ATPase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member. (427 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (537 aa)
lonATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (804 aa)
SGRA_0043Type 4 fimbriae expression regulatory protein pilR; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (549 aa)
SGRA_0036ABC transporter related protein; COG4152 ABC-type uncharacterized transport system, ATPase component. (299 aa)
dnaAChromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (501 aa)
recQ-2COG0514 Superfamily II DNA helicase. (737 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
Server load: low (36%) [HD]