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spoU spoU trmB trmB yjfH yjfH gidB gidB ksgA ksgA SGRA_1881 SGRA_1881 ypsC ypsC SGRA_1551 SGRA_1551 SGRA_1525 SGRA_1525 SGRA_1519 SGRA_1519 hemK hemK SGRA_1339 SGRA_1339 SGRA_1249 SGRA_1249 SGRA_1248 SGRA_1248 SGRA_1117 SGRA_1117 SGRA_1028 SGRA_1028 rsmI rsmI ubiE ubiE mraW mraW SGRA_0702 SGRA_0702 rsmB rsmB prmA prmA gcvT gcvT rlmN rlmN SGRA_0250 SGRA_0250 panB panB thyA thyA glyA glyA SGRA_0717 SGRA_0717 SGRA_3939 SGRA_3939 SGRA_3905 SGRA_3905 hsdM-2 hsdM-2 SGRA_3429 SGRA_3429 hsdM hsdM SGRA_3390 SGRA_3390 SGRA_3354 SGRA_3354 SGRA_3227 SGRA_3227 SGRA_2910 SGRA_2910 rsmD rsmD SGRA_2969 SGRA_2969 rlmI rlmI ybaZ ybaZ SGRA_3145 SGRA_3145 cheR cheR tpmT tpmT ybeA ybeA ermC ermC SGRA_4149 SGRA_4149 rsmE rsmE hsdM-3 hsdM-3 SGRA_4031 SGRA_4031 trmD trmD SGRA_2290 SGRA_2290 SGRA_2367 SGRA_2367 dcm dcm pcm pcm metH metH SGRA_2652 SGRA_2652
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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spoUtRNA/rRNA methyltransferase (SpoU); COG0566 rRNA methylases. (252 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (226 aa)
yjfHRNA methyltransferase, TrmH family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (239 aa)
gidBMethyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (210 aa)
ksgA16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (264 aa)
SGRA_1881RNA methyltransferase YjfH; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (250 aa)
ypsCTHUMP domain-containing protein; COG0116 Predicted N6-adenine-specific DNA methylase; Belongs to the methyltransferase superfamily. (399 aa)
SGRA_1551O-methyltransferase family 3; COG4122 Predicted O-methyltransferase. (214 aa)
SGRA_1525Type 11 methyltransferase; COG0500 SAM-dependent methyltransferases. (263 aa)
SGRA_15193-demethylubiquinone-9 3-methyltransferase; COG0500 SAM-dependent methyltransferases. (216 aa)
hemKN5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; COG2890 Methylase of polypeptide chain release factors. (270 aa)
SGRA_1339COG0566 rRNA methylases. (145 aa)
SGRA_1249O-methyltransferase family 2; COG0500 SAM-dependent methyltransferases. (323 aa)
SGRA_1248O-methyltransferase family 2. (231 aa)
SGRA_1117FkbM family methyltransferase; COG0500 SAM-dependent methyltransferases. (299 aa)
SGRA_1028COG0500 SAM-dependent methyltransferases. (268 aa)
rsmIUroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (252 aa)
ubiEDemethylmenaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (250 aa)
mraWS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (302 aa)
SGRA_070223S rRNA (uracil-5-)-methyltransferase RumA; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (501 aa)
rsmBRibosomal RNA small subunit methyltransferase B; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (405 aa)
prmACOG2264 Ribosomal protein L11 methylase. (276 aa)
gcvTGlycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (368 aa)
rlmNRibosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (348 aa)
SGRA_0250Fmu (sun) domain protein; COG0144 tRNA and rRNA cytosine-C5-methylases. (450 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (435 aa)
SGRA_0717Methyltransferase type 11; COG0500 SAM-dependent methyltransferases. (224 aa)
SGRA_3939COG2020 Putative protein-S-isoprenylcysteine methyltransferase. (248 aa)
SGRA_3905Methyltransferase; COG0500 SAM-dependent methyltransferases. (205 aa)
hsdM-2COG0286 Type I restriction-modification system methyltransferase subunit. (512 aa)
SGRA_3429Putative DNA-binding protein; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). (237 aa)
hsdMCOG0286 Type I restriction-modification system methyltransferase subunit. (501 aa)
SGRA_3390Methyltransferase type 12; COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase. (235 aa)
SGRA_33545-methylaminomethyl-2-thiouridine methyltransferase. (229 aa)
SGRA_3227MCP methyltransferase, CheR-type; COG1352 Methylase of chemotaxis methyl-accepting proteins. (260 aa)
SGRA_2910Uroporphyrin-iii c/tetrapyrrole (corrin/porphyrin) methyltransferase; COG0313 Predicted methyltransferases. (235 aa)
rsmDMethyltransferase; COG0742 N6-adenine-specific methylase. (184 aa)
SGRA_2969Putative SpoU rRNA methylase family protein; COG0566 rRNA methylases. (179 aa)
rlmICOG1092 Predicted SAM-dependent methyltransferases. (408 aa)
ybaZmethylated-DNA-[protein]-cysteine S-methyltransferase; COG0350 Methylated DNA-protein cysteine methyltransferase. (104 aa)
SGRA_3145COG0500 SAM-dependent methyltransferases. (290 aa)
cheRMCP methyltransferase, CheR-type; COG1352 Methylase of chemotaxis methyl-accepting proteins. (280 aa)
tpmTThiopurine S-methyltransferase; COG0500 SAM-dependent methyltransferases. (195 aa)
ybeArRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (157 aa)
ermCMethyltransferase type 11; COG0500 SAM-dependent methyltransferases. (237 aa)
SGRA_4149Methyltransferase type 11; COG0500 SAM-dependent methyltransferases. (243 aa)
rsmE16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (238 aa)
hsdM-3COG0286 Type I restriction-modification system methyltransferase subunit. (780 aa)
SGRA_4031rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (363 aa)
trmDtRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (226 aa)
SGRA_2290N-6 DNA methylase; COG0286 Type I restriction-modification system methyltransferase subunit. (629 aa)
SGRA_2367COG0500 SAM-dependent methyltransferases. (399 aa)
dcmDNA-cytosine methyltransferase; COG0270 Site-specific DNA methylase. (418 aa)
pcmprotein-l-isoaspartate(D-aspartate) o-methyltransferase; COG2518 Protein-L-isoaspartate carboxylmethyltransferase. (219 aa)
metHB12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1225 aa)
SGRA_2652O-methyltransferase-like protein; COG4122 Predicted O-methyltransferase. (290 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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