STRINGSTRING
SGRA_1132 SGRA_1132 SGRA_1158 SGRA_1158 SGRA_1244 SGRA_1244 SGRA_1246 SGRA_1246 SGRA_1288 SGRA_1288 SGRA_1375 SGRA_1375 SGRA_1541 SGRA_1541 SGRA_1554 SGRA_1554 rpoE-5 rpoE-5 rpoE-6 rpoE-6 rpoS rpoS rho rho fnr fnr SGRA_1732 SGRA_1732 dnaG dnaG rpoE-7 rpoE-7 rpoA rpoA SGRA_1892 SGRA_1892 greA greA nusG nusG rpoB rpoB rpoC rpoC nusA nusA rpoE-4 rpoE-4 rpoE-3 rpoE-3 SGRA_0911 SGRA_0911 mraZ mraZ rpoD rpoD SGRA_0764 SGRA_0764 rpoE-2 rpoE-2 rpoE rpoE narL narL SGRA_0495 SGRA_0495 phoB1 phoB1 SGRA_0197 SGRA_0197 SGRA_0177 SGRA_0177 SGRA_0144 SGRA_0144 SGRA_2395 SGRA_2395 rpoE-8 rpoE-8 rpoE-9 rpoE-9 SGRA_2480 SGRA_2480 SGRA_2500 SGRA_2500 SGRA_2546 SGRA_2546 SGRA_2653 SGRA_2653 oxyR oxyR SGRA_2979 SGRA_2979 SGRA_3173 SGRA_3173 SGRA_3261 SGRA_3261 rpoE-10 rpoE-10 SGRA_3372 SGRA_3372 phoB1-2 phoB1-2 SGRA_3560 SGRA_3560 nusB nusB oxyR-2 oxyR-2 oxyR-3 oxyR-3 SGRA_3882 SGRA_3882 SGRA_3957 SGRA_3957 SGRA_4027 SGRA_4027 rpoE-11 rpoE-11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGRA_1132Two component, sigma54 specific, Fis family transcriptional regulator; COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain. (534 aa)
SGRA_1158Two component LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (231 aa)
SGRA_1244Hypothetical protein. (237 aa)
SGRA_1246AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (280 aa)
SGRA_1288Transcriptional regulator, TetR family; COG1309 Transcriptional regulator. (228 aa)
SGRA_1375RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
SGRA_1541COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (241 aa)
SGRA_1554Transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (281 aa)
rpoE-5COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (213 aa)
rpoE-6RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa)
rpoSPutative RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (290 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (589 aa)
fnrCRP family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. (223 aa)
SGRA_1732RNA polymerase, sigma-E factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (683 aa)
rpoE-7RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (332 aa)
SGRA_1892COG2207 AraC-type DNA-binding domain-containing proteins. (296 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (160 aa)
nusGNusG antitermination factor; Participates in transcription elongation, termination and antitermination. (180 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1276 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1420 aa)
nusATranscription elongation factor NusA; Participates in both transcription termination and antitermination. (438 aa)
rpoE-4RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
rpoE-3RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (152 aa)
SGRA_0911tetR family regulatory protein; COG1309 Transcriptional regulator. (211 aa)
mraZMraZ protein; COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family. (153 aa)
rpoDRNA polymerase, sigma 70 subunit, RpoD subfamily protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (290 aa)
SGRA_0764Putative two component, sigma54 specific, transcriptional regulator, Fis family protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (421 aa)
rpoE-2RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
rpoERNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (172 aa)
narLTwo component transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (219 aa)
SGRA_0495Two component transcriptional regulator, LytTR family protein; COG3279 Response regulator of the LytR/AlgR family. (239 aa)
phoB1COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (237 aa)
SGRA_0197RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
SGRA_0177Two component transcriptional regulator, LytTR family protein; COG3279 Response regulator of the LytR/AlgR family. (234 aa)
SGRA_0144Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (310 aa)
SGRA_2395ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (200 aa)
rpoE-8RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
rpoE-9COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
SGRA_2480COG1309 Transcriptional regulator. (194 aa)
SGRA_2500Sigma54 specific transcriptional regulator, Fis family protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (433 aa)
SGRA_2546DNA-directed RNA polymerase, omega subunit. (113 aa)
SGRA_2653Transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. (195 aa)
oxyRRedox-sensitive transcriptional activator OxyR; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (308 aa)
SGRA_2979Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins. (288 aa)
SGRA_3173Regulatory protein tetr; COG1309 Transcriptional regulator. (202 aa)
SGRA_3261Transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. (212 aa)
rpoE-10RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
SGRA_3372Transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (303 aa)
phoB1-2Two component transcriptional regulator, winged helix family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (235 aa)
SGRA_3560COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (291 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (311 aa)
oxyR-2Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (314 aa)
oxyR-3Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (315 aa)
SGRA_3882COG1510 Predicted transcriptional regulators; Belongs to the GbsR family. (218 aa)
SGRA_3957Putative AraC family transcriptional regulator; COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain. (299 aa)
SGRA_4027Putative transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (292 aa)
rpoE-11COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (201 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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