STRINGSTRING
fbaB fbaB pckA pckA eno eno lpd lpd SGRA_0746 SGRA_0746 fbp fbp gapA gapA SGRA_1245 SGRA_1245 SGRA_1247 SGRA_1247 pdhA pdhA SGRA_1893 SGRA_1893 pfk pfk SGRA_2011 SGRA_2011 SGRA_2469 SGRA_2469 pyk pyk pdhB pdhB SGRA_2632 SGRA_2632 tpiA tpiA aceF aceF gpm gpm manA manA acs acs pgk pgk gapA-2 gapA-2 lpd-2 lpd-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fbaBCOG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes. (350 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (537 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
lpdCOG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (472 aa)
SGRA_0746Putative zinc-type alcohol dehydrogenase-like protein; COG1064 Zn-dependent alcohol dehydrogenases. (335 aa)
fbpCOG0158 Fructose-1,6-bisphosphatase. (327 aa)
gapACOG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (495 aa)
SGRA_1245Alcohol dehydrogenase zinc-binding domain protein; COG1064 Zn-dependent alcohol dehydrogenases. (350 aa)
SGRA_1247Phosphoglycerate mutase family protein; COG0406 Fructose-2,6-bisphosphatase. (170 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (335 aa)
SGRA_1893COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (506 aa)
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa)
SGRA_2011HAD-superfamily hydrolase, subfamily IA, variant 3; COG1011 Predicted hydrolase (HAD superfamily). (215 aa)
SGRA_2469COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (517 aa)
pykCOG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa)
pdhBTransketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa)
SGRA_2632COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (471 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (257 aa)
aceFPyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (417 aa)
gpmPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (510 aa)
manABifunctional phosphoglucose/phosphomannose isomerase; COG0166 Glucose-6-phosphate isomerase. (330 aa)
acsAcetyl-coenzyme a synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (633 aa)
pgkCOG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa)
gapA-2Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
lpd-2COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (470 aa)
Your Current Organism:
Saprospira grandis
NCBI taxonomy Id: 984262
Other names: S. grandis str. Lewin, Saprospira grandis str. Lewin, Saprospira grandis strain Lewin
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