STRINGSTRING
rpl24 rpl24 rps4e rps4e VMUT_0108 VMUT_0108 VMUT_0136 VMUT_0136 VMUT_0175 VMUT_0175 tyrS tyrS prf1 prf1 VMUT_0237 VMUT_0237 rps13 rps13 rps17e rps17e metG metG rpl14 rpl14 VMUT_0344 VMUT_0344 rps6e rps6e VMUT_0372 VMUT_0372 pheS pheS rps15 rps15 VMUT_0396 VMUT_0396 lysS lysS VMUT_0449 VMUT_0449 rpl39e rpl39e rps19e rps19e rpl44e rpl44e rps27e rps27e VMUT_0470 VMUT_0470 VMUT_0549 VMUT_0549 rpl12 rpl12 pth pth rpl19e rpl19e rpl18 rpl18 aspS aspS eif1a eif1a gatE gatE rps7 rps7 infB infB rpl24e rpl24e rps27ae rps27ae rpl40e rpl40e rps8e rps8e rps8 rps8 rps28e rps28e rpl7ae rpl7ae rps19p rps19p VMUT_0763 VMUT_0763 rpl37e rpl37e gltX gltX gatD gatD rpl14e rpl14e rps11 rps11 rpl31e rpl31e rpl10e rpl10e alaS alaS rpl10 rpl10 rpl1 rpl1 rpl11 rpl11 spt5 spt5 rpl18a rpl18a VMUT_0935 VMUT_0935 ef1b ef1b rps9 rps9 rpl13 rpl13 rpl18e rpl18e rps24e rps24e VMUT_1164 VMUT_1164 VMUT_1189 VMUT_1189 rpl22 rpl22 eif5a eif5a rpl21e rpl21e hisS hisS cysS cysS VMUT_1267 VMUT_1267 rpl29 rpl29 rps3 rps3 VMUT_1336 VMUT_1336 rpl5 rpl5 VMUT_1353 VMUT_1353 VMUT_1467 VMUT_1467 rps10 rps10 tuf tuf leuS leuS VMUT_1568 VMUT_1568 rpl34e rpl34e rps2 rps2 VMUT_1642 VMUT_1642 rps4 rps4 VMUT_1728 VMUT_1728 rpl35ae rpl35ae VMUT_1737 VMUT_1737 rpl13e rpl13e rps5 rps5 rpl30 rpl30 rpl15 rpl15 rpl3 rpl3 rpl4 rpl4 rpl23 rpl23 thrS thrS rpl37ae rpl37ae VMUT_1831 VMUT_1831 proS proS VMUT_1851 VMUT_1851 VMUT_1852 VMUT_1852 rps14 rps14 argS argS rpl30e rpl30e rps12 rps12 eif6 eif6 VMUT_2110 VMUT_2110 VMUT_2113 VMUT_2113 rpl6 rpl6 rps17 rps17 fusA fusA rpl2 rpl2 VMUT_2243 VMUT_2243 VMUT_2324 VMUT_2324
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl2450S ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit. (159 aa)
rps4e30S ribosomal protein S4E, central domain-containing protein; Belongs to the eukaryotic ribosomal protein eS4 family. (248 aa)
VMUT_0108Deoxyribonuclease. (71 aa)
VMUT_0136asparaginyl-tRNA synthetase. (429 aa)
VMUT_0175Translation initiation factor aIF-2B subunit, conjectural; Belongs to the eIF-2B alpha/beta/delta subunits family. (291 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (374 aa)
prf1Peptide chain release factor 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (385 aa)
VMUT_023730S ribosomal protein S26E. (139 aa)
rps1330S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (158 aa)
rps17e30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (76 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. (584 aa)
rpl1450S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (144 aa)
VMUT_0344glycyl-tRNA synthetase. (591 aa)
rps6e30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (145 aa)
VMUT_0372phenylalanyl-tRNA synthetase subunit beta. (552 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (524 aa)
rps1530S ribosomal protein S15P. (150 aa)
VMUT_0396seryl-tRNA synthetase. (468 aa)
lysSlysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (568 aa)
VMUT_044950S ribosomal protein L15e. (192 aa)
rpl39e50S ribosomal protein L39e; Belongs to the eukaryotic ribosomal protein eL39 family. (54 aa)
rps19e30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (160 aa)
rpl44e50S ribosomal protein L44E; Binds to the 23S rRNA. (94 aa)
rps27e30S ribosomal protein S27E. (71 aa)
VMUT_0470Translation initiation factor 2, alpha subunit. (283 aa)
VMUT_0549Translation initiation factor IF2/IF5. (141 aa)
rpl12Ribosomal protein 60S; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (113 aa)
pthAminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. (121 aa)
rpl19e50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (148 aa)
rpl1850S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (213 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (433 aa)
eif1aS1 IF1 family protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (105 aa)
gatEPutative aspartyl-tRNA(Asn) amidotransferase, B subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (625 aa)
rps730S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (222 aa)
infBTranslation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (598 aa)
rpl24e50S ribosomal protein L24E; Binds to the 23S rRNA. (64 aa)
rps27aeRibosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family. (64 aa)
rpl40e50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa)
rps8e30S ribosomal protein S8e. (133 aa)
rps830S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rps28e30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (81 aa)
rpl7ae50S ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (173 aa)
rps19p30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (199 aa)
VMUT_0763Thioesterase superfamily protein. (160 aa)
rpl37e50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (62 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (588 aa)
gatDglutamyl-tRNA(Gln) amidotransferase, subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (449 aa)
rpl14e50S ribosomal protein L14; Belongs to the eukaryotic ribosomal protein eL14 family. (100 aa)
rps1130S ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (165 aa)
rpl31eRibosomal protein L31e; Belongs to the ribosomal protein L31e family. (108 aa)
rpl10e50S ribosomal protein L10e/L16; Belongs to the universal ribosomal protein uL16 family. (180 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (912 aa)
rpl1050S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (353 aa)
rpl150S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (219 aa)
rpl1150S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (172 aa)
spt5NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (148 aa)
rpl18aRibosomal protein LX. (85 aa)
VMUT_0935aminoacyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (892 aa)
ef1bTranslation elongation factor aEF-1 beta subunit; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (92 aa)
rps930S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (158 aa)
rpl1350S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (195 aa)
rpl18e50S ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL18 family. (122 aa)
rps24e30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (133 aa)
VMUT_1164Selenocysteine-specific translation elongation factor-like protein. (282 aa)
VMUT_1189Hypothetical protein. (46 aa)
rpl2250S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (184 aa)
eif5aTranslation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (132 aa)
rpl21e50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (107 aa)
hisShistidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (430 aa)
cysScysteinyl-tRNA synthetase. (503 aa)
VMUT_1267Hypothetical protein. (188 aa)
rpl2950S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (61 aa)
rps330S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (228 aa)
VMUT_1336Threonyl/alanyl tRNA synthetase SAD. (240 aa)
rpl550S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (197 aa)
VMUT_1353Thioesterase superfamily protein. (169 aa)
VMUT_1467Translation initiation factor SUI1. (125 aa)
rps1030S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa)
tufTranslation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (444 aa)
leuSleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (998 aa)
VMUT_1568Protein synthesis factor GTP-binding protein. (414 aa)
rpl34e50S ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa)
rps230S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (225 aa)
VMUT_1642ABC transporter related protein. (610 aa)
rps430S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (179 aa)
VMUT_1728Hypothetical protein. (668 aa)
rpl35ae50S ribosomal protein L35Ae; Belongs to the eukaryotic ribosomal protein eL33 family. (94 aa)
VMUT_1737TGS domain protein. (392 aa)
rpl13e50S ribosomal protein L13E; Belongs to the eukaryotic ribosomal protein eL13 family. (158 aa)
rps530S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (203 aa)
rpl3050S ribosomal protein L30P. (184 aa)
rpl1550S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (157 aa)
rpl350S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (342 aa)
rpl450S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (278 aa)
rpl2350S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (81 aa)
thrSthreonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (621 aa)
rpl37ae50S ribosomal protein L37Ae; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (92 aa)
VMUT_1831tRNA synthetase class II (D K and N). (357 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (510 aa)
VMUT_1851PUA domain containing protein. (178 aa)
VMUT_1852tRNA-binding domain protein. (112 aa)
rps1430S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (54 aa)
argSarginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (643 aa)
rpl30e50S ribosomal protein L7Ae/L30e/S12e/Gadd45; Belongs to the eukaryotic ribosomal protein eL30 family. (103 aa)
rps1230S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (150 aa)
eif6Putative translation initiation factor eIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (226 aa)
VMUT_2110B3/4 domain protein. (232 aa)
VMUT_2113isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1004 aa)
rpl650S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (190 aa)
rps1730S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (150 aa)
fusATranslation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (739 aa)
rpl250S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (271 aa)
VMUT_224350S ribosomal protein L38. (67 aa)
VMUT_2324tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (356 aa)
Your Current Organism:
Vulcanisaeta moutnovskia
NCBI taxonomy Id: 985053
Other names: V. moutnovskia 768-28, Vulcanisaeta moutnovskia 768-28, Vulcanisaeta moutnovskia str. 768-28, Vulcanisaeta moutnovskia strain 768-28
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