STRINGSTRING
eif6 eif6 thiI thiI VMUT_0088 VMUT_0088 rpl24 rpl24 rps4e rps4e VMUT_0108 VMUT_0108 VMUT_0136 VMUT_0136 VMUT_0175 VMUT_0175 tyrS tyrS VMUT_0205 VMUT_0205 prf1 prf1 VMUT_0222 VMUT_0222 VMUT_0237 VMUT_0237 VMUT_0245 VMUT_0245 VMUT_0257 VMUT_0257 cca cca rps13 rps13 nep1 nep1 tiaS tiaS VMUT_0291 VMUT_0291 VMUT_0298 VMUT_0298 VMUT_0300 VMUT_0300 tgtA tgtA rps17e rps17e metG metG truB truB taw3 taw3 rpl14 rpl14 VMUT_0344 VMUT_0344 rps6e rps6e VMUT_0372 VMUT_0372 pheS pheS VMUT_0385 VMUT_0385 rps15 rps15 VMUT_0391 VMUT_0391 VMUT_0396 VMUT_0396 lysS lysS VMUT_0447 VMUT_0447 VMUT_0449 VMUT_0449 VMUT_0451 VMUT_0451 VMUT_0452 VMUT_0452 rpl39e rpl39e rps19e rps19e VMUT_0464 VMUT_0464 rpl44e rpl44e rps27e rps27e VMUT_0470 VMUT_0470 nop10 nop10 VMUT_0504 VMUT_0504 VMUT_0516 VMUT_0516 VMUT_0524 VMUT_0524 VMUT_0549 VMUT_0549 rpl12 rpl12 pth pth rpl19e rpl19e rpl18 rpl18 aspS aspS VMUT_0616 VMUT_0616 eif1a eif1a gatE gatE rtcB rtcB rps7 rps7 truD truD infB infB rpl24e rpl24e dys dys rps27ae rps27ae VMUT_0735 VMUT_0735 rpl40e rpl40e rps8e rps8e rps8 rps8 rps28e rps28e rpl7ae rpl7ae rps19p rps19p VMUT_0763 VMUT_0763 VMUT_0766 VMUT_0766 rpl37e rpl37e gltX gltX VMUT_0799 VMUT_0799 rnz rnz VMUT_0809 VMUT_0809 gatD gatD kae1 kae1 rpl14e rpl14e rps11 rps11 VMUT_0880 VMUT_0880 rpl31e rpl31e VMUT_0889 VMUT_0889 VMUT_0894 VMUT_0894 rpl10e rpl10e alaS alaS rpl10 rpl10 rpl1 rpl1 rpl11 rpl11 spt5 spt5 rpl18a rpl18a tfe tfe VMUT_0930 VMUT_0930 VMUT_0934 VMUT_0934 VMUT_0935 VMUT_0935 ef1b ef1b VMUT_0961 VMUT_0961 rpoN rpoN rps9 rps9 rpl13 rpl13 rpl18e rpl18e rpoD rpoD VMUT_1117 VMUT_1117 VMUT_1126 VMUT_1126 rps24e rps24e VMUT_1164 VMUT_1164 VMUT_1189 VMUT_1189 rpl22 rpl22 eif5a eif5a rpl21e rpl21e pus10 pus10 hisS hisS cysS cysS VMUT_1267 VMUT_1267 VMUT_1270 VMUT_1270 rpl29 rpl29 rps3 rps3 flpA flpA VMUT_1325 VMUT_1325 VMUT_1336 VMUT_1336 rpl5 rpl5 VMUT_1353 VMUT_1353 VMUT_1382 VMUT_1382 VMUT_1447 VMUT_1447 VMUT_1465 VMUT_1465 VMUT_1467 VMUT_1467 rps10 rps10 tuf tuf leuS leuS VMUT_1568 VMUT_1568 VMUT_1574 VMUT_1574 rpl34e rpl34e rps2 rps2 VMUT_1605 VMUT_1605 VMUT_1615 VMUT_1615 VMUT_1642 VMUT_1642 VMUT_1643 VMUT_1643 VMUT_1669 VMUT_1669 tbp tbp VMUT_1689 VMUT_1689 rps4 rps4 VMUT_1728 VMUT_1728 rpl35ae rpl35ae VMUT_1737 VMUT_1737 tfb tfb rpl13e rpl13e rps5 rps5 rpl30 rpl30 rpl15 rpl15 rpl3 rpl3 rpl4 rpl4 rpl23 rpl23 thrS thrS rpl37ae rpl37ae VMUT_1798 VMUT_1798 VMUT_1799 VMUT_1799 tmcA tmcA VMUT_1817 VMUT_1817 VMUT_1831 VMUT_1831 proS proS VMUT_1851 VMUT_1851 VMUT_1852 VMUT_1852 rps14 rps14 VMUT_1985 VMUT_1985 rpoK rpoK VMUT_2048 VMUT_2048 VMUT_2049 VMUT_2049 argS argS rpoH rpoH VMUT_2058 VMUT_2058 VMUT_2059 VMUT_2059 rpoA2 rpoA2 rpl30e rpl30e nusA nusA rps12 rps12 VMUT_2073 VMUT_2073 VMUT_2076 VMUT_2076 VMUT_2078 VMUT_2078 truA truA VMUT_2086 VMUT_2086 rpoL rpoL VMUT_2110 VMUT_2110 csl4 csl4 VMUT_2113 VMUT_2113 VMUT_2117 VMUT_2117 rpl6 rpl6 rps17 rps17 taw1 taw1 VMUT_2176 VMUT_2176 fusA fusA VMUT_2213 VMUT_2213 VMUT_2218 VMUT_2218 rpl2 rpl2 VMUT_2226 VMUT_2226 VMUT_2243 VMUT_2243 rtcA rtcA VMUT_2291 VMUT_2291 VMUT_2320 VMUT_2320 VMUT_2324 VMUT_2324 VMUT_2325 VMUT_2325 VMUT_2344 VMUT_2344
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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eif6Putative translation initiation factor eIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (226 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (483 aa)
VMUT_0088Hypothetical protein. (79 aa)
rpl2450S ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit. (159 aa)
rps4e30S ribosomal protein S4E, central domain-containing protein; Belongs to the eukaryotic ribosomal protein eS4 family. (248 aa)
VMUT_0108Deoxyribonuclease. (71 aa)
VMUT_0136asparaginyl-tRNA synthetase. (429 aa)
VMUT_0175Translation initiation factor aIF-2B subunit, conjectural; Belongs to the eIF-2B alpha/beta/delta subunits family. (291 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (374 aa)
VMUT_0205Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (375 aa)
prf1Peptide chain release factor 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (385 aa)
VMUT_0222RNA modification enzyme, MiaB family. (452 aa)
VMUT_023730S ribosomal protein S26E. (139 aa)
VMUT_0245GTPase or GTP-binding protein. (371 aa)
VMUT_0257Putative RNA methylase. (198 aa)
ccatRNA cytidylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (456 aa)
rps1330S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (158 aa)
nep1Ribosome biogenesis protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (228 aa)
tiaSHypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (422 aa)
VMUT_0291Transcription factor CBF/NF-Y histone. (76 aa)
VMUT_0298Hypothetical protein. (275 aa)
VMUT_0300Like-Sm ribonucleoprotein core. (140 aa)
tgtAtRNA-guanine transglycosylase, various specificities; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (542 aa)
rps17e30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (76 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. (584 aa)
truBrRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (348 aa)
taw3Hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (213 aa)
rpl1450S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (144 aa)
VMUT_0344glycyl-tRNA synthetase. (591 aa)
rps6e30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (145 aa)
VMUT_0372phenylalanyl-tRNA synthetase subunit beta. (552 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (524 aa)
VMUT_0385Mn2+-dependent serine/threonine protein kinase. (223 aa)
rps1530S ribosomal protein S15P. (150 aa)
VMUT_0391KH type 1 domain protein. (197 aa)
VMUT_0396seryl-tRNA synthetase. (468 aa)
lysSlysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (568 aa)
VMUT_0447Putative RNA-binding protein containing THUMP domain. (316 aa)
VMUT_044950S ribosomal protein L15e. (192 aa)
VMUT_0451Hypothetical protein. (192 aa)
VMUT_0452Hypothetical protein. (104 aa)
rpl39e50S ribosomal protein L39e; Belongs to the eukaryotic ribosomal protein eL39 family. (54 aa)
rps19e30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (160 aa)
VMUT_0464Transcription termination factor Tfs; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (100 aa)
rpl44e50S ribosomal protein L44E; Binds to the 23S rRNA. (94 aa)
rps27e30S ribosomal protein S27E. (71 aa)
VMUT_0470Translation initiation factor 2, alpha subunit. (283 aa)
nop10RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (77 aa)
VMUT_0504Dissimilatory sulfite reductase subunit C. (111 aa)
VMUT_0516Fmu (Sun) domain protein. (404 aa)
VMUT_0524SirA family protein. (82 aa)
VMUT_0549Translation initiation factor IF2/IF5. (141 aa)
rpl12Ribosomal protein 60S; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (113 aa)
pthAminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. (121 aa)
rpl19e50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (148 aa)
rpl1850S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (213 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (433 aa)
VMUT_0616Transcription elongation factor NusA-like protein. (141 aa)
eif1aS1 IF1 family protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (105 aa)
gatEPutative aspartyl-tRNA(Asn) amidotransferase, B subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (625 aa)
rtcBHypothetical protein; Belongs to the RtcB family. (490 aa)
rps730S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (222 aa)
truDtRNA pseudouridine synthase D TruD; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (449 aa)
infBTranslation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (598 aa)
rpl24e50S ribosomal protein L24E; Binds to the 23S rRNA. (64 aa)
dysDeoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. (330 aa)
rps27aeRibosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family. (64 aa)
VMUT_0735Helicase domain protein. (1037 aa)
rpl40e50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa)
rps8e30S ribosomal protein S8e. (133 aa)
rps830S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rps28e30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (81 aa)
rpl7ae50S ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (173 aa)
rps19p30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (199 aa)
VMUT_0763Thioesterase superfamily protein. (160 aa)
VMUT_0766Like-Sm ribonucleoprotein core. (72 aa)
rpl37e50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (62 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (588 aa)
VMUT_0799Histone acetyltransferase, ELP3 family. (508 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (307 aa)
VMUT_0809Dimethyladenosine transferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (276 aa)
gatDglutamyl-tRNA(Gln) amidotransferase, subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (449 aa)
kae1Putative metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. (334 aa)
rpl14e50S ribosomal protein L14; Belongs to the eukaryotic ribosomal protein eL14 family. (100 aa)
rps1130S ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (165 aa)
VMUT_0880THUMP domain protein. (179 aa)
rpl31eRibosomal protein L31e; Belongs to the ribosomal protein L31e family. (108 aa)
VMUT_0889Hypothetical protein. (162 aa)
VMUT_0894Putative RNA methylase. (350 aa)
rpl10e50S ribosomal protein L10e/L16; Belongs to the universal ribosomal protein uL16 family. (180 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (912 aa)
rpl1050S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (353 aa)
rpl150S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (219 aa)
rpl1150S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (172 aa)
spt5NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (148 aa)
rpl18aRibosomal protein LX. (85 aa)
tfeTranscription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...] (178 aa)
VMUT_0930Methyltransferase. (281 aa)
VMUT_0934PP-loop domain protein. (338 aa)
VMUT_0935aminoacyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (892 aa)
ef1bTranslation elongation factor aEF-1 beta subunit; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (92 aa)
VMUT_0961Like-Sm ribonucleoprotein, core. (81 aa)
rpoNRNA polymerase, N/8 Kd subunits; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (68 aa)
rps930S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (158 aa)
rpl1350S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (195 aa)
rpl18e50S ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL18 family. (122 aa)
rpoDRNA polymerase insert; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. (317 aa)
VMUT_1117Hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (148 aa)
VMUT_1126Hypothetical protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (186 aa)
rps24e30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (133 aa)
VMUT_1164Selenocysteine-specific translation elongation factor-like protein. (282 aa)
VMUT_1189Hypothetical protein. (46 aa)
rpl2250S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (184 aa)
eif5aTranslation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (132 aa)
rpl21e50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (107 aa)
pus10THUMP domain-containing protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (412 aa)
hisShistidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (430 aa)
cysScysteinyl-tRNA synthetase. (503 aa)
VMUT_1267Hypothetical protein. (188 aa)
VMUT_1270POP4 domain containing protein. (82 aa)
rpl2950S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (61 aa)
rps330S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (228 aa)
flpAFibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (238 aa)
VMUT_1325tRNA (guanine-N(2)-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (386 aa)
VMUT_1336Threonyl/alanyl tRNA synthetase SAD. (240 aa)
rpl550S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (197 aa)
VMUT_1353Thioesterase superfamily protein. (169 aa)
VMUT_1382Methyltransferase type 11. (223 aa)
VMUT_1447tRNA-splicing endonuclease subunit alpha. (184 aa)
VMUT_1465DNA-directed RNA polymerase. (197 aa)
VMUT_1467Translation initiation factor SUI1. (125 aa)
rps1030S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa)
tufTranslation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (444 aa)
leuSleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (998 aa)
VMUT_1568Protein synthesis factor GTP-binding protein. (414 aa)
VMUT_1574tRNA (guanine-N1-)-methyltransferase. (355 aa)
rpl34e50S ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa)
rps230S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (225 aa)
VMUT_1605Zinc finger TFIIB-type domain protein. (311 aa)
VMUT_1615Hypothetical protein. (145 aa)
VMUT_1642ABC transporter related protein. (610 aa)
VMUT_1643Beta-aspartate methyltransferase. (263 aa)
VMUT_166930S ribosomal protein S25e. (113 aa)
tbp2-alkenal reductase; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (193 aa)
VMUT_1689DNA-directed RNA polymerase subunit P. (80 aa)
rps430S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (179 aa)
VMUT_1728Hypothetical protein. (668 aa)
rpl35ae50S ribosomal protein L35Ae; Belongs to the eukaryotic ribosomal protein eL33 family. (94 aa)
VMUT_1737TGS domain protein. (392 aa)
tfbTranscription factor TFIIB cyclin-related protein; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (336 aa)
rpl13e50S ribosomal protein L13E; Belongs to the eukaryotic ribosomal protein eL13 family. (158 aa)
rps530S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (203 aa)
rpl3050S ribosomal protein L30P. (184 aa)
rpl1550S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (157 aa)
rpl350S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (342 aa)
rpl450S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (278 aa)
rpl2350S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (81 aa)
thrSthreonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (621 aa)
rpl37ae50S ribosomal protein L37Ae; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (92 aa)
VMUT_1798Brix domain-containing protein; Probably involved in the biogenesis of the ribosome. (176 aa)
VMUT_1799Hypothetical protein. (50 aa)
tmcAPutative P-loop ATPase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (799 aa)
VMUT_1817AIR synthase related protein domain protein. (330 aa)
VMUT_1831tRNA synthetase class II (D K and N). (357 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (510 aa)
VMUT_1851PUA domain containing protein. (178 aa)
VMUT_1852tRNA-binding domain protein. (112 aa)
rps1430S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (54 aa)
VMUT_1985Thg1 domain containing protein. (242 aa)
rpoKDNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (117 aa)
VMUT_2048Peptidase S26B, signal peptidase. (144 aa)
VMUT_2049Ribosomal-protein-alanine acetyltransferase. (183 aa)
argSarginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (643 aa)
rpoHRNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (90 aa)
VMUT_2058DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1141 aa)
VMUT_2059DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (891 aa)
rpoA2DNA-directed RNA polymerase, subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (391 aa)
rpl30e50S ribosomal protein L7Ae/L30e/S12e/Gadd45; Belongs to the eukaryotic ribosomal protein eL30 family. (103 aa)
nusANusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family. (150 aa)
rps1230S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (150 aa)
VMUT_2073Sjogrens syndrome scleroderma autoantigen 1. (133 aa)
VMUT_2076SirA family protein. (81 aa)
VMUT_2078Hypothetical protein. (82 aa)
truAtRNA-pseudouridine synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (272 aa)
VMUT_2086RNA-binding protein FAU-1. (484 aa)
rpoLDNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (91 aa)
VMUT_2110B3/4 domain protein. (232 aa)
csl4RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa)
VMUT_2113isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1004 aa)
VMUT_2117GTPase or GTP-binding protein K06947. (438 aa)
rpl650S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (190 aa)
rps1730S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (150 aa)
taw1Wyosine base formation; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (367 aa)
VMUT_2176Hypothetical protein. (207 aa)
fusATranslation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (739 aa)
VMUT_2213Fe-S oxidoreductase. (310 aa)
VMUT_2218Beta-lactamase domain protein. (249 aa)
rpl250S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (271 aa)
VMUT_2226tRNA intron endonuclease, catalytic domain-containing protein. (197 aa)
VMUT_224350S ribosomal protein L38. (67 aa)
rtcARNA-3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (350 aa)
VMUT_2291Putative circadian clock protein, KaiC. (289 aa)
VMUT_2320Hypothetical protein. (82 aa)
VMUT_2324tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (356 aa)
VMUT_2325PUA domain containing protein. (149 aa)
VMUT_2344SirA family protein. (94 aa)
Your Current Organism:
Vulcanisaeta moutnovskia
NCBI taxonomy Id: 985053
Other names: V. moutnovskia 768-28, Vulcanisaeta moutnovskia 768-28, Vulcanisaeta moutnovskia str. 768-28, Vulcanisaeta moutnovskia strain 768-28
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