STRINGSTRING
AET56952.1 AET56952.1 fabZ fabZ AET57957.1 AET57957.1 AET57958.1 AET57958.1 AET57959.1 AET57959.1 fabH fabH AET58834.1 AET58834.1 fabH-2 fabH-2 AET59924.1 AET59924.1 accD accD accA accA AET60190.1 AET60190.1 AET60249.1 AET60249.1 tmcAL tmcAL fapR fapR plsX plsX fabH-3 fabH-3 AET60334.1 AET60334.1 AET60335.1 AET60335.1 acpP acpP AET60337.1 AET60337.1 AET60706.1 AET60706.1 AET60709.1 AET60709.1 AET60711.1 AET60711.1 AET60804.1 AET60804.1 AET60805.1 AET60805.1 AET60806.1 AET60806.1 AET60898.1 AET60898.1 AET60899.1 AET60899.1 AET61187.1 AET61187.1 AET61188.1 AET61188.1 AET61189.1 AET61189.1 AET61198.1 AET61198.1 AET61202.1 AET61202.1 AET61298.1 AET61298.1 AET61537.1 AET61537.1 AET61538.1 AET61538.1 AET61703.1 AET61703.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AET56952.1COG0236 Acyl carrier protein. (92 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase fabz; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (148 aa)
AET57957.1Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins. (2524 aa)
AET57958.1COG1020 Non-ribosomal peptide synthetase modules and related proteins. (2543 aa)
AET57959.1COG1020 Non-ribosomal peptide synthetase modules and related proteins. (2332 aa)
fabH3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (316 aa)
AET58834.1Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (254 aa)
fabH-23-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (329 aa)
AET59924.14'-phosphopantetheinyl transferase sfp (Surfactin synthetase-activating enzyme); COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (232 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (297 aa)
accAAcetyl-coenzyme a carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (327 aa)
AET60190.13-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
AET60249.1COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family. (1231 aa)
tmcALNucleotidyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (411 aa)
fapRFatty acid biosynthesis transcriptional regulator; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism. (198 aa)
plsXGlycerol-3-phosphate acyltransferase plsx; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (330 aa)
fabH-33-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (329 aa)
AET60334.1COG0331 (acyl-carrier-protein) S-malonyltransferase. (313 aa)
AET60335.13-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier protein reductase); Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa)
AET60337.13-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
AET60706.1Gramicidin S biosynthesis protein; COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis. (274 aa)
AET60709.1COG1020 Non-ribosomal peptide synthetase modules and related proteins. (10743 aa)
AET60711.1COG1020 Non-ribosomal peptide synthetase modules and related proteins. (2956 aa)
AET60804.1Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins. (451 aa)
AET60805.1Bacitracin synthetase 3; COG1020 Non-ribosomal peptide synthetase modules and related proteins. (218 aa)
AET60806.1Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins. (810 aa)
AET60898.1Phenylalanine racemase; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family. (1143 aa)
AET60899.1COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family. (2847 aa)
AET61187.1COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family. (1562 aa)
AET61188.1COG1020 Non-ribosomal peptide synthetase modules and related proteins. (4228 aa)
AET61189.1Pks acyltransferase domain protein; COG0331 (acyl-carrier-protein) S-malonyltransferase. (407 aa)
AET61198.1COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis. (244 aa)
AET61202.1Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (420 aa)
AET61298.1COG1020 Non-ribosomal peptide synthetase modules and related proteins. (3740 aa)
AET61537.1Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
AET61538.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (163 aa)
AET61703.1COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III. (328 aa)
Your Current Organism:
Paenibacillus terrae
NCBI taxonomy Id: 985665
Other names: P. terrae HPL-003, Paenibacillus sp. HPL-003, Paenibacillus terrae HPL-003, Paenibacillus terrae str. HPL-003, Paenibacillus terrae strain HPL-003
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