STRINGSTRING
hemC hemC thiE thiE mqnE mqnE ctaB ctaB pcrB pcrB AET57668.1 AET57668.1 metK metK murA murA AET58324.1 AET58324.1 AET58328.1 AET58328.1 speE speE murA-2 murA-2 AET58676.1 AET58676.1 AET58797.1 AET58797.1 AET59242.1 AET59242.1 AET59872.1 AET59872.1 mqnC mqnC AET59894.1 AET59894.1 AET60407.1 AET60407.1 AET60550.1 AET60550.1 AET60617.1 AET60617.1 miaA miaA AET60783.1 AET60783.1 AET61263.1 AET61263.1 nadA nadA ubiX ubiX AET61403.1 AET61403.1 AET61405.1 AET61405.1 ribH ribH AET61453.1 AET61453.1 AET61529.1 AET61529.1 aroA aroA murA-3 murA-3 AET61984.1 AET61984.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
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hemCPhosphate ABC transporter ATPase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (308 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (220 aa)
mqnERadical sam domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (368 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. (314 aa)
pcrBPcrB protein; Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond- formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales. (230 aa)
AET57668.1Hypothetical protein; COG2089 Sialic acid synthase. (342 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (400 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (449 aa)
AET58324.1COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (312 aa)
AET58328.1Dihydropteroate synthase (dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (288 aa)
speESpermidine synthase (Putrescine aminopropyltransferase) (SPDSY); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (275 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa)
AET58676.1Aromatic acid decarboxylase; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase. (196 aa)
AET58797.1COG2873 O-acetylhomoserine sulfhydrylase. (430 aa)
AET59242.1COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (307 aa)
AET59872.1ATP:cob(i)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (187 aa)
mqnCThiamine biosynthesis enzyme thiH; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (377 aa)
AET59894.1Phospho-2-dehydro-3-deoxyheptonate aldolase (phospho-2-keto-3-deoxyheptonate aldolase); COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase. (345 aa)
AET60407.1Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (255 aa)
AET60550.1Fosfomycin resistance protein FosB; COG0346 Lactoylglutathione lyase and related lyases. (66 aa)
AET60617.1O-acetylserine lyase; COG0031 Cysteine synthase. (307 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (326 aa)
AET60783.1Transcriptional regulator TenI; COG0352 Thiamine monophosphate synthase. (206 aa)
AET61263.1COG0421 Spermidine synthase. (248 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (368 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (220 aa)
AET61403.1COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family. (289 aa)
AET61405.1Hypothetical protein; COG0142 Geranylgeranyl pyrophosphate synthase. (289 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (154 aa)
AET61453.1COG0307 Riboflavin synthase alpha chain. (221 aa)
AET61529.1COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (307 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (430 aa)
murA-3UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (436 aa)
AET61984.1Geranyltranstransferase; COG0142 Geranylgeranyl pyrophosphate synthase. (797 aa)
Your Current Organism:
Paenibacillus terrae
NCBI taxonomy Id: 985665
Other names: P. terrae HPL-003, Paenibacillus sp. HPL-003, Paenibacillus terrae HPL-003, Paenibacillus terrae str. HPL-003, Paenibacillus terrae strain HPL-003
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