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nadA nadA AET56859.1 AET56859.1 AET56923.1 AET56923.1 AET56941.1 AET56941.1 AET57262.1 AET57262.1 AET57477.1 AET57477.1 ppc ppc AET57519.1 AET57519.1 AET57854.1 AET57854.1 AET58186.1 AET58186.1 AET58320.1 AET58320.1 AET58328.1 AET58328.1 AET58329.1 AET58329.1 AET58330.1 AET58330.1 dapA dapA AET58889.1 AET58889.1 AET59231.1 AET59231.1 aroE aroE aroD aroD aroK aroK AET59342.1 AET59342.1 AET59351.1 AET59351.1 AET59383.1 AET59383.1 AET59422.1 AET59422.1 AET59519.1 AET59519.1 AET59766.1 AET59766.1 AET60180.1 AET60180.1 asd asd AET60431.1 AET60431.1 dapA-2 dapA-2 AET60594.1 AET60594.1 AET60663.1 AET60663.1 AET60799.1 AET60799.1 AET60819.1 AET60819.1 AET60837.1 AET60837.1 fumC fumC AET60918.1 AET60918.1 AET61019.1 AET61019.1 aspA aspA AET61081.1 AET61081.1 aspA-2 aspA-2 dapB dapB AET61395.1 AET61395.1 aroB aroB aroC aroC AET61441.1 AET61441.1 lysA lysA AET61547.1 AET61547.1 dapF dapF AET61627.1 AET61627.1 aroA aroA AET61669.1 AET61669.1 AET61833.1 AET61833.1 aroE-2 aroE-2 aspA-3 aspA-3 AET61932.1 AET61932.1 dapH dapH AET61980.1 AET61980.1 AET61998.1 AET61998.1 AET62009.1 AET62009.1 AET62277.1 AET62277.1
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (368 aa)
AET56859.1Malate dehydrogenase; COG0281 Malic enzyme. (573 aa)
AET56923.1Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (451 aa)
AET56941.1COG0019 Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (428 aa)
AET57262.1Amidohydrolase; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (405 aa)
AET57477.1Amidohydrolase; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (394 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (930 aa)
AET57519.1Malate dehydrogenase; COG0281 Malic enzyme. (566 aa)
AET57854.1Amidohydrolase; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (409 aa)
AET58186.1Dihydrodipicolinate reductase. (72 aa)
AET58320.1COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (296 aa)
AET58328.1Dihydropteroate synthase (dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (288 aa)
AET58329.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa)
AET58330.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (182 aa)
dapAHypothetical protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
AET58889.1Hypothetical protein; COG1228 Imidazolonepropionase and related amidohydrolases. (436 aa)
AET59231.1Amidohydrolase; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; Belongs to the peptidase M20A family. (402 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (296 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (254 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (190 aa)
AET59342.1COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (295 aa)
AET59351.1Amidohydrolase; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; Belongs to the peptidase M20A family. (406 aa)
AET59383.1COG0281 Malic enzyme. (467 aa)
AET59422.1Bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; COG1605 Chorismate mutase. (361 aa)
AET59519.1COG0067 Glutamate synthase domain 1. (1532 aa)
AET59766.1Malate dehydrogenase (oxaloacetate-decarboxylating); COG0281 Malic enzyme. (472 aa)
AET60180.1Amidohydrolase; COG1228 Imidazolonepropionase and related amidohydrolases. (389 aa)
asdAspartate-semialdehyde dehydrogenase (ASA dehydrogenase); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (345 aa)
AET60431.1Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. (405 aa)
dapA-2Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa)
AET60594.1Hypothetical protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (382 aa)
AET60663.1COG0019 Diaminopimelate decarboxylase. (410 aa)
AET60799.1COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (495 aa)
AET60819.1COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; Belongs to the peptidase M20A family. (392 aa)
AET60837.1Crowt peptidase m20d; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (390 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa)
AET60918.1Oxalate decarboxylase; COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes. (388 aa)
AET61019.1Malic protein NAD-binding protein; COG0281 Malic enzyme. (475 aa)
aspACOG1027 Aspartate ammonia-lyase. (472 aa)
AET61081.1Peptidase M20; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (379 aa)
aspA-2COG1027 Aspartate ammonia-lyase. (482 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa)
AET61395.1Chorismate mutase (CM); Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (124 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (364 aa)
aroCChorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (389 aa)
AET61441.1N-acyl-L-amino acid amidohydrolase; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (397 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (455 aa)
AET61547.1COG0527 Aspartokinases; Belongs to the aspartokinase family. (417 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (277 aa)
AET61627.1Hypothetical protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (401 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (430 aa)
AET61669.1Malate dehydrogenase; COG0281 Malic enzyme. (572 aa)
AET61833.1Malate dehydrogenase (oxaloacetate-decarboxylating); COG0281 Malic enzyme. (401 aa)
aroE-2Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (289 aa)
aspA-3COG1027 Aspartate ammonia-lyase. (469 aa)
AET61932.1Hypothetical protein; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (378 aa)
dapHTetrahydrodipicolinate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (237 aa)
AET61980.1Aminobenzoyl-glutamate utilization protein B; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (478 aa)
AET61998.1COG0076 Glutamate decarboxylase and related PLP-dependent proteins. (468 aa)
AET62009.1COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (423 aa)
AET62277.1COG0281 Malic enzyme. (390 aa)
Your Current Organism:
Paenibacillus terrae
NCBI taxonomy Id: 985665
Other names: P. terrae HPL-003, Paenibacillus sp. HPL-003, Paenibacillus terrae HPL-003, Paenibacillus terrae str. HPL-003, Paenibacillus terrae strain HPL-003
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