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| | AET60208.1 | Glutamate-rich protein grpb. (175 aa) |
| | AET56927.1 | Allantoate amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (409 aa) |
| | AET56944.1 | Hypothetical protein. (511 aa) |
| | AET56950.1 | COG0439 Biotin carboxylase. (458 aa) |
| | AET57018.1 | Rela/spot domain protein; COG2357 Uncharacterized protein conserved in bacteria. (246 aa) |
| | deoD | COG0813 Purine-nucleoside phosphorylase. (235 aa) |
| | dacA | L-arabinose isomerase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (277 aa) |
| | adk | Adenylate kinase (ATP-amp transphosphorylase) (ak)(superoxide-inducible protein 16) (soi16); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | AET57707.1 | Hypothetical protein. (72 aa) |
| | atpC | F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (137 aa) |
| | atpD | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (466 aa) |
| | atpG | F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (288 aa) |
| | atpA | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (504 aa) |
| | atpH | ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (181 aa) |
| | atpF | ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (162 aa) |
| | atpE | F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (74 aa) |
| | atpB | ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (274 aa) |
| | ade | COG1001 Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (575 aa) |
| | gpmA | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (249 aa) |
| | xpt | Adenine/guanine phosphoribosyltransferase family protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (205 aa) |
| | AET58103.1 | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. (118 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa) |
| | AET58284.1 | Hypothetical protein; COG1078 HD superfamily phosphohydrolases. (427 aa) |
| | AET58305.1 | COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain. (499 aa) |
| | AET58317.1 | COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa) |
| | coaX | Hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (255 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) |
| | AET58395.1 | COG0191 Fructose/tagatose bisphosphate aldolase. (284 aa) |
| | pgk | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (393 aa) |
| | tpiA | Triosephosphate isomerase (Triose-phosphate isomerase); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa) |
| | gpmI | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa) |
| | eno | Enolase (2-phosphoglycerate dehydratase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa) |
| | AET58577.1 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (471 aa) |
| | AET58640.1 | COG0516 IMP dehydrogenase/GMP reductase. (58 aa) |
| | AET58838.1 | COG2357 Uncharacterized protein conserved in bacteria. (267 aa) |
| | guaA | GMP synthase (glutamin-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (512 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (391 aa) |
| | AET59110.1 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (432 aa) |
| | purC | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. (293 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (81 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I (FGAM synthase I); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...] (229 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (747 aa) |
| | purF | Amidophosphoribosyltransferase precursor (glutamine phosphoribosylpyrophosphate amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (493 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. (346 aa) |
| | purN | Folate-dependent phosphoribosylglycinamide formyltransferase purn; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (204 aa) |
| | purH | Bifunctional purine biosynthesis protein purH; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). (515 aa) |
| | purD | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (422 aa) |
| | folD | FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa) |
| | AET59282.1 | Hypothetical protein. (446 aa) |
| | AET59328.1 | COG0191 Fructose/tagatose bisphosphate aldolase. (290 aa) |
| | AET59354.1 | Allantoate amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (410 aa) |
| | AET59356.1 | COG3257 Uncharacterized protein, possibly involved in glyoxylate utilization. (255 aa) |
| | AET59402.1 | COG2508 Regulator of polyketide synthase expression. (554 aa) |
| | AET59512.1 | COG0232 dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (471 aa) |
| | purU | Formyltetrahydrofolate deformylase (formyl-FH(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (299 aa) |
| | pgi | Phosphoglucose isomerase (pgi); COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. (451 aa) |
| | AET59802.1 | Hypothetical protein; COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases. (142 aa) |
| | odhA | 2-oxoglutarate dehydrogenase E1 component (alpha-ketoglutarate dehydrogenase); E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). (963 aa) |
| | AET59825.1 | 2-oxoglutarate dehydrogenase, e2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (437 aa) |
| | AET59914.1 | COG2508 Regulator of polyketide synthase expression. (511 aa) |
| | AET59921.1 | COG1607 Acyl-CoA hydrolase. (171 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (297 aa) |
| | accA | Acetyl-coenzyme a carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (327 aa) |
| | AET59982.1 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa) |
| | coaE | Dephospho-CoA kinase (Dephosphocoenzyme A kinase); Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (323 aa) |
| | AET60161.1 | COG2357 Uncharacterized protein conserved in bacteria. (270 aa) |
| | xpt-2 | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (190 aa) |
| | ade-2 | COG1001 Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (613 aa) |
| | coaD | Phosphopantetheine adenylyltransferase (Pantetheine-phosphate adenylyltransferase); Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (173 aa) |
| | AET60372.1 | Flagellum-specific ATP synthase; COG1157 Flagellar biosynthesis/type III secretory pathway ATPase. (439 aa) |
| | AET60795.1 | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (537 aa) |
| | AET60947.1 | COG0777 Acetyl-CoA carboxylase beta subunit. (557 aa) |
| | AET61072.1 | Hypothetical protein. (176 aa) |
| | AET61152.1 | PucR family transcriptional regulator; COG2508 Regulator of polyketide synthase expression. (533 aa) |
| | AET61184.1 | Acetyl-coenzyme A synthetase (acetate--CoA ligase); COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (529 aa) |
| | AET61265.1 | COG0563 Adenylate kinase and related kinases. (226 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (394 aa) |
| | ackA | Acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (147 aa) |
| | AET61481.1 | Lipoamide acyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (467 aa) |
| | folD-2 | Methylenetetrahydrofolate dehydrogenase (nadp(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa) |
| | AET61537.1 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | AET61609.1 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (437 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (190 aa) |
| | AET61640.1 | COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (571 aa) |
| | AET61973.1 | Transcriptional regulator, PucR family protein; COG2508 Regulator of polyketide synthase expression. (542 aa) |
| | AET61999.1 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (337 aa) |
| | AET62278.1 | COG3051 Citrate lyase, alpha subunit. (519 aa) |
| | AET62279.1 | COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (293 aa) |
| | AET62293.1 | GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (725 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa) |
