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| | trpC | COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (264 aa) |
| | AET56816.1 | COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (332 aa) |
| | thiE | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (220 aa) |
| | AET56951.1 | COG0535 Predicted Fe-S oxidoreductases. (397 aa) |
| | mqnE | Radical sam domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (368 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (300 aa) |
| | AET57137.1 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (340 aa) |
| | AET57166.1 | Nitropropane dioxygenase / trans-enoyl-CoA reductase family protein; COG2070 Dioxygenases related to 2-nitropropane dioxygenase. (357 aa) |
| | AET57177.1 | Oxidoreductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (1004 aa) |
| | AET57219.1 | COG2070 Dioxygenases related to 2-nitropropane dioxygenase. (322 aa) |
| | AET57220.1 | COG2070 Dioxygenases related to 2-nitropropane dioxygenase. (321 aa) |
| | AET57364.1 | 12-oxophytodienoate reductase-like protein 1; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (373 aa) |
| | deoC | Deoxyribose-phosphate aldolase (phosphodeoxyriboaldolase); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa) |
| | AET57668.1 | Hypothetical protein; COG2089 Sialic acid synthase. (342 aa) |
| | fni | Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (366 aa) |
| | AET57842.1 | Anaerobic ribonucleoside-triphosphate reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (165 aa) |
| | AET57888.1 | ABC transporter like protein; Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA. (185 aa) |
| | AET57897.1 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (214 aa) |
| | AET57941.1 | COG0269 3-hexulose-6-phosphate synthase and related proteins. (211 aa) |
| | AET57983.1 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (342 aa) |
| | AET58017.1 | Glycerol uptake operon antiterminator regulatory protein; COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding). (211 aa) |
| | AET58019.1 | Enoate reductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (649 aa) |
| | AET58086.1 | NADH-dependent flavin oxidoreductase, oye family protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (373 aa) |
| | pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (310 aa) |
| | rlmN | Hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (365 aa) |
| | AET58132.1 | Glycosyl transferase family 2; COG0535 Predicted Fe-S oxidoreductases. (319 aa) |
| | AET58320.1 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (296 aa) |
| | AET58332.1 | tRNA-dihydrouridine synthase 1; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (342 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) |
| | pdxS | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (293 aa) |
| | AET58395.1 | COG0191 Fructose/tagatose bisphosphate aldolase. (284 aa) |
| | AET58398.1 | Hypothetical protein; COG1180 Pyruvate-formate lyase-activating enzyme. (423 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. (243 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF (IGP synthase cyclase subunit); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa) |
| | tpiA | Triosephosphate isomerase (Triose-phosphate isomerase); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa) |
| | AET58522.1 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase. (216 aa) |
| | AET58605.1 | Arylsulfatase regulator (Fe-S oxidoreductase); COG0535 Predicted Fe-S oxidoreductases. (473 aa) |
| | AET58610.1 | Arylsulfatase regulator (Fe-S oxidoreductase). (299 aa) |
| | AET58640.1 | COG0516 IMP dehydrogenase/GMP reductase. (58 aa) |
| | nanE | N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (239 aa) |
| | dapA | Hypothetical protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa) |
| | AET58813.1 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (374 aa) |
| | AET58879.1 | Nitropropane dioxygenase / trans-enoyl-CoA reductase family protein; COG2070 Dioxygenases related to 2-nitropropane dioxygenase. (355 aa) |
| | AET58902.1 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (346 aa) |
| | AET58906.1 | NADH:flavin oxidoreductase/NADH oxidase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (359 aa) |
| | AET58923.1 | COG0036 Pentose-5-phosphate-3-epimerase. (218 aa) |
| | AET59059.1 | Hypothetical protein; COG0535 Predicted Fe-S oxidoreductases. (347 aa) |
| | AET59193.1 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (329 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (254 aa) |
| | AET59328.1 | COG0191 Fructose/tagatose bisphosphate aldolase. (290 aa) |
| | AET59342.1 | COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (295 aa) |
| | AET59368.1 | Nitrogenase cofactor biosynthesis protein NifB; COG0535 Predicted Fe-S oxidoreductases. (499 aa) |
| | AET59376.1 | COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. (378 aa) |
| | AET59422.1 | Bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; COG1605 Chorismate mutase. (361 aa) |
| | queE | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (290 aa) |
| | AET59519.1 | COG0067 Glutamate synthase domain 1. (1532 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (513 aa) |
| | mqnC | Thiamine biosynthesis enzyme thiH; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (377 aa) |
| | AET59894.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase (phospho-2-keto-3-deoxyheptonate aldolase); COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase. (345 aa) |
| | AET59955.1 | COG0535 Predicted Fe-S oxidoreductases. (376 aa) |
| | AET60031.1 | COG0535 Predicted Fe-S oxidoreductases. (291 aa) |
| | AET60155.1 | Putative alpha-isopropylmalate/homocitrate synthase family transferase; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. (538 aa) |
| | pyrD-2 | Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (364 aa) |
| | tal | Transaldolase 2; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa) |
| | AET60299.1 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (375 aa) |
| | dapA-2 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa) |
| | AET60461.1 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (490 aa) |
| | AET60723.1 | Hypothetical protein; COG2100 Predicted Fe-S oxidoreductase. (292 aa) |
| | AET60783.1 | Transcriptional regulator TenI; COG0352 Thiamine monophosphate synthase. (206 aa) |
| | thiG | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (255 aa) |
| | AET60824.1 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (340 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (335 aa) |
| | leuA-2 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (514 aa) |
| | AET60917.1 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (673 aa) |
| | AET61171.1 | Alpha-galactosidase 1 (Melibiase); COG3345 Alpha-galactosidase. (758 aa) |
| | AET61267.1 | Glycoside hydrolase, clan gh-d; COG3345 Alpha-galactosidase. (429 aa) |
| | thiH | COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (470 aa) |
| | AET61337.1 | COG0502 Biotin synthase and related enzymes. (336 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa) |
| | trpF | COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (228 aa) |
| | AET61562.1 | Pyruvate formate-lyase activating enzyme (PFL-activating enzyme); Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (252 aa) |
| | AET61601.1 | Had-superfamily hydrolase, subfamily iib; COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa) |
| | rlmN-2 | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (362 aa) |
| | pyrF | Orotidine 5-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (245 aa) |
| | AET61844.1 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (395 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (337 aa) |
| | moaA-2 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (338 aa) |
| | AET62040.1 | Radical sam domain protein; COG0535 Predicted Fe-S oxidoreductases. (368 aa) |
| | AET62117.1 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (38 aa) |
