STRINGSTRING
AET57175.1 AET57175.1 AET57902.1 AET57902.1 AET58571.1 AET58571.1 ldh ldh AET59129.1 AET59129.1 iolA iolA AET59572.1 AET59572.1 AET59573.1 AET59573.1 AET59574.1 AET59574.1 AET59575.1 AET59575.1 accD accD accA accA AET60033.1 AET60033.1 sucC sucC sucD sucD AET60455.1 AET60455.1 AET60796.1 AET60796.1 ldh-2 ldh-2 gldA gldA AET61184.1 AET61184.1 ackA ackA mgsA mgsA AET61456.1 AET61456.1 AET61457.1 AET61457.1 AET61481.1 AET61481.1 AET61482.1 AET61482.1 AET61483.1 AET61483.1 AET61484.1 AET61484.1 AET61537.1 AET61537.1 AET61538.1 AET61538.1 AET61563.1 AET61563.1 AET61640.1 AET61640.1 gldA-2 gldA-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AET57175.1COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (333 aa)
AET57902.1Protein yhdH; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (335 aa)
AET58571.1Reductase; COG0656 Aldo/keto reductases, related to diketogulonate reductase. (280 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (318 aa)
AET59129.1Oxidoreductase, aldo/keto reductase family protein; COG0656 Aldo/keto reductases, related to diketogulonate reductase. (274 aa)
iolAMethylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. (492 aa)
AET59572.13-ketoacid-coenzyme a transferase1; COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit. (218 aa)
AET59573.1COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit. (221 aa)
AET59574.1COG4689 Acetoacetate decarboxylase. (246 aa)
AET59575.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (297 aa)
accAAcetyl-coenzyme a carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (327 aa)
AET60033.1COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (461 aa)
sucCsuccinyl-CoA synthetase subunit beta (SCS-beta); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
sucDsuccinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (309 aa)
AET60455.1Propanediol utilization phosphotransacylase; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (190 aa)
AET60796.1COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (473 aa)
ldh-2L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (309 aa)
gldACOG0371 Glycerol dehydrogenase and related enzymes. (372 aa)
AET61184.1Acetyl-coenzyme A synthetase (acetate--CoA ligase); COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (529 aa)
ackAAcetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (145 aa)
AET61456.1COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. (762 aa)
AET61457.1COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (337 aa)
AET61481.1Lipoamide acyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (467 aa)
AET61482.12-oxoisovalerate dehydrogenase subunit beta; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (328 aa)
AET61483.13-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (342 aa)
AET61484.1COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (473 aa)
AET61537.1Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
AET61538.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (163 aa)
AET61563.1Formate acetyltransferase 1 (pyruvate formate-lyase 1); COG1882 Pyruvate-formate lyase. (753 aa)
AET61640.1COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (571 aa)
gldA-2COG0371 Glycerol dehydrogenase and related enzymes. (367 aa)
Your Current Organism:
Paenibacillus terrae
NCBI taxonomy Id: 985665
Other names: P. terrae HPL-003, Paenibacillus sp. HPL-003, Paenibacillus terrae HPL-003, Paenibacillus terrae str. HPL-003, Paenibacillus terrae strain HPL-003
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.