(32 nodes) Acyl transferase/acyl hydrolase/lysophospholipase network (Leptosphaeria maculans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LEMA_P057650.1	Similar to polyketide synthase. (2140 aa)
	LEMA_P049480.1	Similar to malonyl-CoA-acyl carrier protein transacylase. (415 aa)
	LEMA_P008370.1	PNPLA domain-containing protein. (678 aa)
	LEMA_P006610.1	Uncharacterized protein. (2938 aa)
	LEMA_P004990.1	Lysophospholipase. (653 aa)
	PKS2	Highly reducing polyketide synthase PKS2; Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of phomenoic acid, a long chain aliphatic carboxylic acid that does not appear to be essential for pathogenicity but may play a role in allowing to outcompete other fungi in the environmental niche via its antifungal properties. The polyketide synthase produces the long methylated aliphatic carboxylic acid chain of phomenoic acid (Probable). The cluster-specific cytochrome P450 monooxygenase may then hydroxylate the methyl group of carbon 31 (Probable). [...] (2543 aa)
	LEMA_P000820.1	Similar to polyketide synthase. (2565 aa)
	LEMA_P010040.1	PNPLA domain-containing protein. (744 aa)
	LEMA_P009410.1	Uncharacterized protein. (1466 aa)
	LEMA_P020790.1	PNPLA domain-containing protein. (686 aa)
	LEMA_P017310.1	Similar to polyketide synthase. (2589 aa)
	LEMA_P076060.1	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. (1523 aa)
	LEMA_P073040.1	Similar to fatty acid synthase beta subunit; Belongs to the fungal fatty acid synthetase subunit beta family. (2109 aa)
	LEMA_P073030.1	Similar to fatty acid synthase; Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family. (1861 aa)
	pks5	Highly reducing polyketide synthase pks5; Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of abscisic acid (ABA), a phytohormone that acts antagonistically toward salicylic acid (SA), jasmonic acid (JA) and ethylene (ETH) signaling, to impede plant defense responses. The first step of the pathway catalyzes the reaction from farnesyl diphosphate to alpha-ionylideneethane performed by the alpha-ionylideneethane synthase abl3 via a three-step reaction mechanism involving 2 neutral intermediates, beta-farnesene and allofarnesene (By similarity). [...] (2569 aa)
	LEMA_P086730.1	Carrier domain-containing protein. (1899 aa)
	LEMA_P083630.1	Lysophospholipase. (822 aa)
	LEMA_P082310.1	Similar to polyketide synthase. (2558 aa)
	LEMA_P082100.1	Uncharacterized protein. (433 aa)
	LEMA_P082090.1	Similar to fatty acid synthase beta subunit; Belongs to the fungal fatty acid synthetase subunit beta family. (1883 aa)
	LEMA_P081920.1	Similar to polyketide synthase. (2046 aa)
	LEMA_P098490.1	Similar to polyketide synthase. (2165 aa)
	LEMA_P098050.1	Uncharacterized protein. (1363 aa)
	LEMA_P023590.1	PNPLA domain-containing protein. (377 aa)
	LEMA_P031340.1	PNPLA domain-containing protein. (537 aa)
	LEMA_P116030.1	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family. (875 aa)
	LEMA_P117970.1	Carrier domain-containing protein. (3275 aa)
	LEMA_P119710.1	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family. (827 aa)
	LEMA_P121590.1	PNPLA domain-containing protein. (505 aa)
	LEMA_P039980.1	PNPLA domain-containing protein. (362 aa)
	LEMA_P056040.1	PNPLA domain-containing protein. (608 aa)
	LEMA_P057720.1	Carrier domain-containing protein. (2615 aa)

Your Current Organism:

Leptosphaeria maculans

NCBI taxonomy Id: 985895
Other names: L. maculans JN3, Leptosphaeria maculans JN3, Leptosphaeria maculans v23.1.3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LEMA_P000820.1	LEMA_P049480.1	E5ADK6	E5R4W9	Similar to polyketide synthase.	Similar to malonyl-CoA-acyl carrier protein transacylase.	0.647
LEMA_P000820.1	LEMA_P086730.1	E5ADK6	E5A739	Similar to polyketide synthase.	Carrier domain-containing protein.	0.619
LEMA_P004990.1	LEMA_P076060.1	E5AES3	E5A8S2	Lysophospholipase.	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	0.795
LEMA_P004990.1	LEMA_P119710.1	E5AES3	E4ZT49	Lysophospholipase.	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	0.754
LEMA_P009410.1	LEMA_P083630.1	E5ACF2	E5A679	Uncharacterized protein.	Lysophospholipase.	0.491
LEMA_P017310.1	LEMA_P049480.1	E5AAB0	E5R4W9	Similar to polyketide synthase.	Similar to malonyl-CoA-acyl carrier protein transacylase.	0.647
LEMA_P017310.1	LEMA_P086730.1	E5AAB0	E5A739	Similar to polyketide synthase.	Carrier domain-containing protein.	0.634
LEMA_P023590.1	LEMA_P083630.1	E4ZWZ7	E5A679	PNPLA domain-containing protein.	Lysophospholipase.	0.491
LEMA_P031340.1	LEMA_P083630.1	E4ZWK6	E5A679	PNPLA domain-containing protein.	Lysophospholipase.	0.491
LEMA_P039980.1	LEMA_P083630.1	E4ZP72	E5A679	PNPLA domain-containing protein.	Lysophospholipase.	0.491
LEMA_P049480.1	LEMA_P000820.1	E5R4W9	E5ADK6	Similar to malonyl-CoA-acyl carrier protein transacylase.	Similar to polyketide synthase.	0.647
LEMA_P049480.1	LEMA_P017310.1	E5R4W9	E5AAB0	Similar to malonyl-CoA-acyl carrier protein transacylase.	Similar to polyketide synthase.	0.647
LEMA_P049480.1	LEMA_P057650.1	E5R4W9	E4ZHG1	Similar to malonyl-CoA-acyl carrier protein transacylase.	Similar to polyketide synthase.	0.639
LEMA_P049480.1	LEMA_P057720.1	E5R4W9	E4ZI77	Similar to malonyl-CoA-acyl carrier protein transacylase.	Carrier domain-containing protein.	0.647
LEMA_P049480.1	LEMA_P073030.1	E5R4W9	E5A7W9	Similar to malonyl-CoA-acyl carrier protein transacylase.	Similar to fatty acid synthase; Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.	0.763
LEMA_P049480.1	LEMA_P073040.1	E5R4W9	E5A7X0	Similar to malonyl-CoA-acyl carrier protein transacylase.	Similar to fatty acid synthase beta subunit; Belongs to the fungal fatty acid synthetase subunit beta family.	0.763
LEMA_P049480.1	LEMA_P081920.1	E5R4W9	E5A5Q5	Similar to malonyl-CoA-acyl carrier protein transacylase.	Similar to polyketide synthase.	0.647
LEMA_P049480.1	LEMA_P082090.1	E5R4W9	E5A5S2	Similar to malonyl-CoA-acyl carrier protein transacylase.	Similar to fatty acid synthase beta subunit; Belongs to the fungal fatty acid synthetase subunit beta family.	0.592
LEMA_P049480.1	LEMA_P082310.1	E5R4W9	E5A5U7	Similar to malonyl-CoA-acyl carrier protein transacylase.	Similar to polyketide synthase.	0.647
LEMA_P049480.1	LEMA_P086730.1	E5R4W9	E5A739	Similar to malonyl-CoA-acyl carrier protein transacylase.	Carrier domain-containing protein.	0.942