(9 nodes) CoA-ligase activity network (Methanothrix soehngenii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	acsA-3	Acetyl-coenzyme A synthetase. (662 aa)
	acsA-4	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (672 aa)
	MCON_0780	Acyl-coenzyme A synthetase. (633 aa)
	paaK	Protein involved in phenylacetate-CoA ligase activity. (434 aa)
	paaK-2	Phenylacetate-coenzyme A ligase. (427 aa)
	paaK-3	Phenylacetate-coenzyme A ligase. (443 aa)
	acsA	Acetyl-coenzyme A synthetase; Protein involved in acetate-CoA ligase activity, AMP binding and acetyl-CoA biosynthetic process from acetate. (656 aa)
	acsA-5	Acetyl-coenzyme A synthetase. (661 aa)
	acsA-2	Acetyl-coenzyme A synthetase. (661 aa)

Your Current Organism:

Methanothrix soehngenii

NCBI taxonomy Id: 990316
Other names: M. soehngenii GP6, Methanosaeta concilii DSM 3671, Methanosaeta concilii GP6, Methanothrix soehngenii DSM 3671, Methanothrix soehngenii GP6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCON_0780	acsA	MCON_0780	MCON_0556	Acyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase; Protein involved in acetate-CoA ligase activity, AMP binding and acetyl-CoA biosynthetic process from acetate.	0.714
MCON_0780	acsA-2	MCON_0780	MCON_0558	Acyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.713
MCON_0780	acsA-3	MCON_0780	MCON_0559	Acyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.710
MCON_0780	acsA-4	MCON_0780	MCON_0561	Acyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.713
MCON_0780	acsA-5	MCON_0780	MCON_2868	Acyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.712
acsA	MCON_0780	MCON_0556	MCON_0780	Acetyl-coenzyme A synthetase; Protein involved in acetate-CoA ligase activity, AMP binding and acetyl-CoA biosynthetic process from acetate.	Acyl-coenzyme A synthetase.	0.714
acsA	acsA-2	MCON_0556	MCON_0558	Acetyl-coenzyme A synthetase; Protein involved in acetate-CoA ligase activity, AMP binding and acetyl-CoA biosynthetic process from acetate.	Acetyl-coenzyme A synthetase.	0.657
acsA	acsA-3	MCON_0556	MCON_0559	Acetyl-coenzyme A synthetase; Protein involved in acetate-CoA ligase activity, AMP binding and acetyl-CoA biosynthetic process from acetate.	Acetyl-coenzyme A synthetase.	0.657
acsA	acsA-4	MCON_0556	MCON_0561	Acetyl-coenzyme A synthetase; Protein involved in acetate-CoA ligase activity, AMP binding and acetyl-CoA biosynthetic process from acetate.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.658
acsA	acsA-5	MCON_0556	MCON_2868	Acetyl-coenzyme A synthetase; Protein involved in acetate-CoA ligase activity, AMP binding and acetyl-CoA biosynthetic process from acetate.	Acetyl-coenzyme A synthetase.	0.657
acsA-2	MCON_0780	MCON_0558	MCON_0780	Acetyl-coenzyme A synthetase.	Acyl-coenzyme A synthetase.	0.713
acsA-2	acsA	MCON_0558	MCON_0556	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase; Protein involved in acetate-CoA ligase activity, AMP binding and acetyl-CoA biosynthetic process from acetate.	0.657
acsA-2	acsA-3	MCON_0558	MCON_0559	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.781
acsA-2	acsA-4	MCON_0558	MCON_0561	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.726
acsA-2	acsA-5	MCON_0558	MCON_2868	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.653
acsA-3	MCON_0780	MCON_0559	MCON_0780	Acetyl-coenzyme A synthetase.	Acyl-coenzyme A synthetase.	0.710
acsA-3	acsA	MCON_0559	MCON_0556	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase; Protein involved in acetate-CoA ligase activity, AMP binding and acetyl-CoA biosynthetic process from acetate.	0.657
acsA-3	acsA-2	MCON_0559	MCON_0558	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.781
acsA-3	acsA-4	MCON_0559	MCON_0561	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.780
acsA-3	acsA-5	MCON_0559	MCON_2868	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.655

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