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| | ENSBTAP00000056656 | Tr-type G domain-containing protein. (74 aa) |
| | LEPROTL1 | Leptin receptor overlapping transcript-like 1; Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability (By similarity). Belongs to the OB-RGRP/VPS55 family. (171 aa) |
| | FSTL1 | Follistatin-related protein 1; May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin (By similarity). (312 aa) |
| | CD34 | CD34 molecule. (386 aa) |
| | ENSBTAP00000073267 | Tr-type G domain-containing protein. (76 aa) |
| | TFPI | Tissue factor pathway inhibitor. (304 aa) |
| | ACTBL2 | Actin beta like 2. (376 aa) |
| | LAMA2-2 | Uncharacterized protein. (924 aa) |
| | NOTUM | Notum, palmitoleoyl-protein carboxylesterase. (500 aa) |
| | ABI3BP | Fibronectin type-III domain-containing protein. (386 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | COL5A2 | Collagen type V alpha 2 chain. (1336 aa) |
| | ENSBTAP00000071921 | Tr-type G domain-containing protein. (74 aa) |
| | ENSBTAP00000071751 | IL3Ra_N domain-containing protein. (143 aa) |
| | PEG10 | CCHC-type domain-containing protein. (405 aa) |
| | ECSCR | Endothelial cell-specific chemotaxis regulator; Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2 (By similarity). Belongs to the ECSCR family. (359 aa) |
| | EFEMP2 | EGF containing fibulin extracellular matrix protein 2. (450 aa) |
| | LIFR | LIF receptor subunit alpha. (1095 aa) |
| | EIF4EBP2 | Uncharacterized protein. (120 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (585 aa) |
| | ENSBTAP00000068799 | Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (170 aa) |
| | CRYBG1 | Crystallin beta-gamma domain containing 1; Belongs to the beta/gamma-crystallin family. (2118 aa) |
| | HNRNPR | Heterogeneous nuclear ribonucleoprotein R. (641 aa) |
| | LRPAP1 | LDL receptor related protein associated protein 1. (440 aa) |
| | KLF6 | Kruppel like factor 6. (309 aa) |
| | CSF2RA-2 | Fibronectin type-III domain-containing protein. (335 aa) |
| | TMEM43 | Uncharacterized protein. (404 aa) |
| | FAM49B | Protein FAM49B. (359 aa) |
| | BSDC1 | BSD domain-containing protein 1. (462 aa) |
| | PAPPA | Pappalysin 1. (1632 aa) |
| | CMTM3 | MARVEL domain-containing protein. (300 aa) |
| | ENSBTAP00000065697 | Uncharacterized protein. (52 aa) |
| | ATP13A3 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1276 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (621 aa) |
| | PDE8B | Phosphodiesterase. (873 aa) |
| | ENSBTAP00000065364 | MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (467 aa) |
| | NET1 | Neuroepithelial cell transforming 1. (574 aa) |
| | SUMF2 | Inactive C-alpha-formylglycine-generating enzyme 2; Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1. Belongs to the sulfatase-modifying factor family. (315 aa) |
| | EMC1 | ER membrane protein complex subunit 1. (998 aa) |
| | PDE8A | Phosphodiesterase. (867 aa) |
| | ADAMTSL4 | ADAMTS like 4. (1070 aa) |
| | RHOBTB3 | Rho related BTB domain containing 3. (982 aa) |
| | LAMA2 | Laminin subunit alpha 2. (2052 aa) |
| | IFI6 | Interferon alpha-inducible protein 6; Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis (By similarity). However, it has also been shown to have a pro- apoptotic activity (By similarity). May have an antiviral activity (By similarity); Belongs to the IFI6/IFI27 family. (134 aa) |
| | LOC404103 | Spleen trypsin inhibitor III. (143 aa) |
| | TACC2 | Transforming acidic coiled-coil containing protein 2. (2625 aa) |
| | SPP1 | Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. (338 aa) |
| | UNK | Unk zinc finger. (811 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (376 aa) |
| | URM1 | Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for co [...] (186 aa) |
| | PAEP | Beta-lactoglobulin; Primary component of whey, it binds retinol and is probably involved in the transport of that molecule; Belongs to the calycin superfamily. Lipocalin family. (245 aa) |
| | LVRN | Aminopeptidase. (989 aa) |
| | PSME3 | Proteasome activator subunit 3. (265 aa) |
| | TTC7B | Tetratricopeptide repeat domain 7B. (909 aa) |
| | EEF1A1 | Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (462 aa) |
| | ENSBTAP00000060062 | Uncharacterized protein. (170 aa) |
| | EPS8L1 | EPS8 like 1. (769 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (841 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (886 aa) |
| | ENSBTAP00000058833 | Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (169 aa) |
| | RARS2 | Probable arginine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (617 aa) |
| | HOXB9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa) |
| | PDE4DIP | Phosphodiesterase 4D interacting protein. (2509 aa) |
| | ENSBTAP00000056870 | Tr-type G domain-containing protein. (120 aa) |
| | TWIST1 | Twist family bHLH transcription factor 1. (201 aa) |
| | TNFSF18 | TNF superfamily member 18. (178 aa) |
| | SETD5 | SET domain containing 5. (1497 aa) |
| | LOC515276 | Galectin. (120 aa) |
| | CSF2RA | Colony stimulating factor 2 receptor alpha subunit. (387 aa) |
| | AVPR2 | Vasopressin V2 receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption (By similarity). (370 aa) |
| | RTL1 | Retrotransposon-like protein 1; Plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta. (1331 aa) |
| | RTL5 | Retrotransposon Gag like 5. (592 aa) |
| | G3N0F2_BOVIN | PB1 domain-containing protein. (347 aa) |
| | G3MYE5_BOVIN | Uncharacterized protein. (207 aa) |
| | ITGBL1 | Integrin subunit beta like 1. (496 aa) |
| | RBM12 | RNA binding motif protein 12. (953 aa) |
| | EFHB | EF-hand domain family member B. (877 aa) |
| | KRT23 | Keratin 23; Belongs to the intermediate filament family. (415 aa) |
| | HPS1 | HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (702 aa) |
| | F1MQX4_BOVIN | Uncharacterized protein. (190 aa) |
| | E1BED8_BOVIN | Tr-type G domain-containing protein. (120 aa) |
| | SRSF3 | Serine/arginine-rich splicing factor 3; Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing. Also functions as export adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA- binding activity. [...] (164 aa) |
| | ENG | ZP domain-containing protein. (650 aa) |
| | KCNN4 | Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4. (257 aa) |
| | CSE1L | Exportin-2; Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause releas [...] (971 aa) |
| | E1B9F6_BOVIN | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (440 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (430 aa) |
| | IRF1 | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] (322 aa) |
| | PHLDA2 | Pleckstrin homology-like domain family A member 2; Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity). (142 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | LHX9 | LIM/homeobox protein Lhx9; Involved in gonadal development. (378 aa) |
| | ARNTL2 | Aryl hydrocarbon receptor nuclear translocator like 2. (587 aa) |
| | SLC2A3 | Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. (494 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E-binding protein 1; Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. (118 aa) |
| | PLPP5 | Phospholipid phosphatase 5. (264 aa) |
| | MUC15 | Mucin-15. (330 aa) |
| | SLC19A3 | Solute carrier family 19 member 3. (485 aa) |
| | PHACTR2 | Phosphatase and actin regulator. (558 aa) |
| | PRSS8 | Serine protease 8; Belongs to the peptidase S1 family. (343 aa) |
| | ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa) |
| | CTSB | Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). (335 aa) |
| | TNFSF15 | Tumor necrosis factor ligand 1B. (256 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (317 aa) |
| | CENPO | Centromere protein O; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex (By similarity). (296 aa) |
| | PTPA | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine- protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the var [...] (324 aa) |
| | CORO1B | Coronin; Belongs to the WD repeat coronin family. (488 aa) |
| | EEF1A2 | Elongation factor 1-alpha 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (463 aa) |
| | TWIST2 | Twist family bHLH transcription factor 2. (160 aa) |
| | MAFF | Transcription factor MafF; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. (172 aa) |
| | CHAMP1 | Chromosome alignment maintaining phosphoprotein 1. (804 aa) |
| | FAU | Ubiquitin-like protein FUBI. (133 aa) |
| | DUSP5 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (457 aa) |
| | SLC19A2 | Solute carrier family 19 member 2. (496 aa) |
| | THY1 | Thy-1 cell surface antigen. (161 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (287 aa) |
| | UNC45A | Unc-45 myosin chaperone A. (944 aa) |
| | TMEM109 | Transmembrane protein 109. (243 aa) |
| | SEMA3F | Semaphorin 3F; Belongs to the semaphorin family. (792 aa) |
| | PAPPA2 | Pappalysin 2. (1791 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity). (209 aa) |
| | CYB561A3 | Cytochrome b ascorbate-dependent protein 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity). (265 aa) |
| | ALS2CL | ALS2 C-terminal-like protein; Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics (By similarity). (953 aa) |
| | ZFAT | Zinc finger and AT-hook domain containing. (1240 aa) |
| | DLX3 | Distal-less homeobox 3. (287 aa) |
| | ZC3H11A | ZC3H11A protein. (816 aa) |
| | FGF5 | Fibroblast growth factor 5; Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase (By similarity). (270 aa) |
| | AFP | Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. (610 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa) |
| | GDAP2 | Ganglioside-induced differentiation-associated protein 2; Belongs to the GDAP2 family. (498 aa) |
| | KRT7 | Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells; Belongs to the intermediate filament family. (466 aa) |
| | TFPI2 | Tissue factor pathway inhibitor 2; May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. (234 aa) |
| | C15H11orf34 | Placenta-expressed transcript 1 protein; Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle (By similarity). (275 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | TREML2 | Triggering receptor expressed on myeloid cells like 2. (436 aa) |
| | GDF15 | Growth differentiation factor 15. (308 aa) |
| | F1MUF2_BOVIN | Galectin. (173 aa) |
| | SYDE1 | Synapse defective Rho GTPase homolog 1. (720 aa) |
| | MCL1 | MCL1 protein. (350 aa) |
| | GRAMD2B | GRAM domain containing 2B. (455 aa) |
| | CCL27 | C-C motif chemokine ligand 27. (119 aa) |
| | CLEC1A | C-type lectin domain family 1 member A. (278 aa) |
| | YEATS2 | YEATS domain containing 2. (1412 aa) |
| | ETV2 | ETS variant 2. (332 aa) |
| | CSF3R | Colony stimulating factor 3 receptor. (841 aa) |
| | FABP7 | Fatty acid-binding protein, brain; FABP are thought to play a role in the intracellular transport of long chain fatty acids and their acyl-CoA esters. Binds oleic and palmitic acids but not palmitoyl CoA. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) |
| | RRM1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (454 aa) |
| | GAB3 | GRB2 associated binding protein 3. (585 aa) |
| | ZDHHC16 | Palmitoyltransferase ZDHHC16; Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6 (By similarity). Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization (By similarity). Also required for eye development (By similarity). Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function (By similarity). May play a role in DNA damage response (By similarity). May be involved in apoptosis regu [...] (377 aa) |
| | SLC29A2 | Solute carrier family 29 member 2. (456 aa) |
| | FAM124B | Protein FAM124B; Belongs to the FAM124 family. (461 aa) |
| | TLL2 | Metalloendopeptidase. (1020 aa) |
| | LENG9 | Leukocyte receptor cluster member 9. (535 aa) |
| | IER3 | Immediate early response 3. (156 aa) |
| | EIF3K | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa) |
| | COPS7A | COP9 signalosome subunit 7A. (275 aa) |
| | TIMP2 | Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family. (235 aa) |
| | PGRMC2 | Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (247 aa) |
| | ANGPTL1 | Angiopoietin-related protein 1. (491 aa) |
| | RXFP1 | Relaxin family peptide receptor 1. (759 aa) |
| | RASA1 | Ras GTPase-activating protein 1; Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21. (1044 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (236 aa) |
| | PCDH12 | Protocadherin 12. (1197 aa) |
| | CTDSP1 | CTD small phosphatase 1. (260 aa) |
| | DUSP9 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (380 aa) |
| | EXPH5 | Exophilin 5. (1933 aa) |
| | GCM1 | Glial cells missing transcription factor 1. (433 aa) |
| | UBA52 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa) |
| | F13A1 | Coagulation factor XIII A chain; Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. (732 aa) |
| | NID1 | NID1 protein. (1241 aa) |
| | LMAN1 | Lectin, mannose binding 1. (518 aa) |
| | PCSK6 | Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (956 aa) |
| | P4HA3 | Prolyl 4-hydroxylase subunit alpha-3; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. (544 aa) |
| | ACTL8 | Actin like 8; Belongs to the actin family. (365 aa) |
| | GLMP | Glycosylated lysosomal membrane protein; Belongs to the GLMP family. (404 aa) |
| | TMBIM4 | Transmembrane BAX inhibitor motif containing 4; Belongs to the BI1 family. (238 aa) |
| | LOXL2 | Lysyl oxidase homolog 2; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Shows no activity against histone H3 when it is trimethylated on 'Lys- 9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2). Also mediates deamination of methylated TAF10, a member o [...] (774 aa) |
| | ACTG1 | Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. (375 aa) |
| | VMAC | Vimentin-type intermediate filament-associated coiled-coil protein. (166 aa) |
| | TLL1 | Metalloendopeptidase. (1013 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (582 aa) |
| | IGFBP2 | Insulin-like growth factor-binding protein 2; Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. (317 aa) |
| | COPZ1 | Coatomer subunit zeta-1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-disso [...] (177 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (573 aa) |
| | MMAB | Corrinoid adenosyltransferase; Adenosyltransferase involved in intracellular vitamin B12 metabolism. Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer taht is stimulated by ATP-binding to MMAB and gated by MMAA. (241 aa) |
| | KLHDC2 | Kelch domain-containing protein 2; Represses CREB3-mediated transcription by interfering with CREB3-DNA binding. (406 aa) |
| | CCNL2 | Cyclin L2; Belongs to the cyclin family. (520 aa) |
| | ACP5 | Tartrate-resistant acid phosphatase type 5. (343 aa) |
| | PHC2 | Polyhomeotic homolog 2. (854 aa) |
| | DGKE | Diacylglycerol kinase. (564 aa) |
| | PKIB | cAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (79 aa) |
| | CXHXorf40A | Uncharacterized protein. (172 aa) |
| | SRPX | Sushi repeat containing protein X-linked. (459 aa) |
| | SKIL | SKI like proto-oncogene. (684 aa) |
| | NFE2L3 | Nuclear factor, erythroid 2 like 3. (695 aa) |
| | MYLIP | Myosin regulatory light chain interacting protein. (380 aa) |
| | KIAA1324L | UPF0577 protein KIAA1324-like homolog. (959 aa) |
| | TMBIM1 | Transmembrane BAX inhibitor motif containing 1; Belongs to the BI1 family. (308 aa) |
| | EDEM2 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (578 aa) |
| | CHST1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (411 aa) |
| | TFG | TFG protein. (401 aa) |
| | CIRBP | Cold inducible RNA binding protein. (213 aa) |
| | ZRANB1 | Ubiquitin thioesterase ZRANB1; Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling (By similarity); Belongs to the peptidase C64 family. (735 aa) |
| | ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif 9. (1937 aa) |
| | DDI1 | Protein DDI1 homolog 1; Probable aspartic protease (By similarity). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2. Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (By similarity). (396 aa) |
| | GMPR2 | GMP reductase 2; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (Probable). Plays a role in modulating cellular differentiation (By similarity). (348 aa) |
| | UBA2 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (640 aa) |
| | LAS1L | LAS1 like, ribosome biogenesis factor. (773 aa) |
| | TFAP2C | Transcription factor AP-2 gamma (Activating enhancer binding protein 2 gamma). (450 aa) |
| | VGLL1 | Vestigial like family member 1. (240 aa) |
| | NR2C2AP | Nuclear receptor 2C2-associated protein; May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes. (140 aa) |
| | BMP1 | Metalloendopeptidase. (988 aa) |
| | KRT8 | Keratin, type II cytoskeletal 8; Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle; Belongs to the intermediate filament family. (478 aa) |
| | BCL2A1 | Bcl-2-related protein A1; Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11 (By similarity). (175 aa) |
| | RPS17 | 40S ribosomal protein S17; Belongs to the eukaryotic ribosomal protein eS17 family. (205 aa) |
| | STAU1 | Staufen double-stranded RNA binding protein 1. (577 aa) |
| | PRDM14 | PR/SET domain 14. (571 aa) |
| | NECTIN4 | Nectin-4; Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. (510 aa) |
