Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARL13B | GPR161 | ENSBTAP00000006796 | ENSBTAP00000071010 | ADP ribosylation factor like GTPase 13B. | G protein-coupled receptor 161; Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signalin [...] | 0.848 |
| ARL13B | INPP5E | ENSBTAP00000006796 | ENSBTAP00000001784 | ADP ribosylation factor like GTPase 13B. | Inositol polyphosphate-5-phosphatase E. | 0.966 |
| ARL13B | PDE6D | ENSBTAP00000006796 | ENSBTAP00000058012 | ADP ribosylation factor like GTPase 13B. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. [...] | 0.929 |
| ARL13B | TULP3 | ENSBTAP00000006796 | ENSBTAP00000021105 | ADP ribosylation factor like GTPase 13B. | Tubby-like protein; Belongs to the TUB family. | 0.816 |
| GPR161 | ARL13B | ENSBTAP00000071010 | ENSBTAP00000006796 | G protein-coupled receptor 161; Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signalin [...] | ADP ribosylation factor like GTPase 13B. | 0.848 |
| GPR161 | INPP5E | ENSBTAP00000071010 | ENSBTAP00000001784 | G protein-coupled receptor 161; Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signalin [...] | Inositol polyphosphate-5-phosphatase E. | 0.596 |
| GPR161 | TULP3 | ENSBTAP00000071010 | ENSBTAP00000021105 | G protein-coupled receptor 161; Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signalin [...] | Tubby-like protein; Belongs to the TUB family. | 0.914 |
| INPP5E | ARL13B | ENSBTAP00000001784 | ENSBTAP00000006796 | Inositol polyphosphate-5-phosphatase E. | ADP ribosylation factor like GTPase 13B. | 0.966 |
| INPP5E | GPR161 | ENSBTAP00000001784 | ENSBTAP00000071010 | Inositol polyphosphate-5-phosphatase E. | G protein-coupled receptor 161; Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signalin [...] | 0.596 |
| INPP5E | PDE6D | ENSBTAP00000001784 | ENSBTAP00000058012 | Inositol polyphosphate-5-phosphatase E. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. [...] | 0.965 |
| INPP5E | TULP3 | ENSBTAP00000001784 | ENSBTAP00000021105 | Inositol polyphosphate-5-phosphatase E. | Tubby-like protein; Belongs to the TUB family. | 0.610 |
| PDE6D | ARL13B | ENSBTAP00000058012 | ENSBTAP00000006796 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. [...] | ADP ribosylation factor like GTPase 13B. | 0.929 |
| PDE6D | INPP5E | ENSBTAP00000058012 | ENSBTAP00000001784 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. [...] | Inositol polyphosphate-5-phosphatase E. | 0.965 |
| PDE6D | TULP3 | ENSBTAP00000058012 | ENSBTAP00000021105 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. [...] | Tubby-like protein; Belongs to the TUB family. | 0.460 |
| TULP3 | ARL13B | ENSBTAP00000021105 | ENSBTAP00000006796 | Tubby-like protein; Belongs to the TUB family. | ADP ribosylation factor like GTPase 13B. | 0.816 |
| TULP3 | GPR161 | ENSBTAP00000021105 | ENSBTAP00000071010 | Tubby-like protein; Belongs to the TUB family. | G protein-coupled receptor 161; Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signalin [...] | 0.914 |
| TULP3 | INPP5E | ENSBTAP00000021105 | ENSBTAP00000001784 | Tubby-like protein; Belongs to the TUB family. | Inositol polyphosphate-5-phosphatase E. | 0.610 |
| TULP3 | PDE6D | ENSBTAP00000021105 | ENSBTAP00000058012 | Tubby-like protein; Belongs to the TUB family. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (By similarity). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. [...] | 0.460 |