node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FZD1 | FZD2 | ENSBTAP00000002720 | ENSBTAP00000056239 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.514 |
FZD1 | LRP5 | ENSBTAP00000002720 | ENSBTAP00000007756 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.984 |
FZD1 | SFRP1 | ENSBTAP00000002720 | ENSBTAP00000039575 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Secreted frizzled-related protein 1; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metane [...] | 0.760 |
FZD1 | WNT1 | ENSBTAP00000002720 | ENSBTAP00000020414 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.989 |
FZD1 | WNT10B | ENSBTAP00000002720 | ENSBTAP00000020402 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.922 |
FZD1 | WNT2B | ENSBTAP00000002720 | ENSBTAP00000018985 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.940 |
FZD1 | WNT3A | ENSBTAP00000002720 | ENSBTAP00000048402 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.962 |
FZD1 | WNT4 | ENSBTAP00000002720 | ENSBTAP00000069426 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.892 |
FZD2 | FZD1 | ENSBTAP00000056239 | ENSBTAP00000002720 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.514 |
FZD2 | FZD3 | ENSBTAP00000056239 | ENSBTAP00000068662 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.560 |
FZD2 | LRP5 | ENSBTAP00000056239 | ENSBTAP00000007756 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.981 |
FZD2 | SFRP1 | ENSBTAP00000056239 | ENSBTAP00000039575 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Secreted frizzled-related protein 1; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metane [...] | 0.827 |
FZD2 | WNT1 | ENSBTAP00000056239 | ENSBTAP00000020414 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.967 |
FZD2 | WNT10B | ENSBTAP00000056239 | ENSBTAP00000020402 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.845 |
FZD2 | WNT2B | ENSBTAP00000056239 | ENSBTAP00000018985 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.894 |
FZD2 | WNT3A | ENSBTAP00000056239 | ENSBTAP00000048402 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.967 |
FZD2 | WNT4 | ENSBTAP00000056239 | ENSBTAP00000069426 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.954 |
FZD3 | FZD2 | ENSBTAP00000068662 | ENSBTAP00000056239 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.560 |
FZD3 | LRP5 | ENSBTAP00000068662 | ENSBTAP00000007756 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.968 |
FZD3 | SFRP1 | ENSBTAP00000068662 | ENSBTAP00000039575 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. | Secreted frizzled-related protein 1; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metane [...] | 0.713 |