| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FOS | FOSB | ENSBTAP00000005660 | ENSBTAP00000010762 | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | FosB proto-oncogene, AP-1 transcription factor subunit. | 0.994 |
| FOS | FOSL1 | ENSBTAP00000005660 | ENSBTAP00000008136 | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | FOS like 1, AP-1 transcription factor subunit. | 0.965 |
| FOS | FOSL2 | ENSBTAP00000005660 | ENSBTAP00000032838 | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | FOS like 2, AP-1 transcription factor subunit. | 0.947 |
| FOS | JUN | ENSBTAP00000005660 | ENSBTAP00000005279 | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28. Binds to the USP28 promoter; Belongs to the bZIP family. Jun subfamily. | 0.999 |
| FOS | JUNB | ENSBTAP00000005660 | ENSBTAP00000015987 | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | Transcription factor jun-B; Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3' (By similarity); Belongs to the bZIP family. Jun subfamily. | 0.998 |
| FOS | JUND | ENSBTAP00000005660 | ENSBTAP00000059607 | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | Transcription factor jun-D; Transcription factor binding AP-1 sites. Belongs to the bZIP family. Jun subfamily. | 0.999 |
| FOSB | FOS | ENSBTAP00000010762 | ENSBTAP00000005660 | FosB proto-oncogene, AP-1 transcription factor subunit. | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | 0.994 |
| FOSB | FOSL1 | ENSBTAP00000010762 | ENSBTAP00000008136 | FosB proto-oncogene, AP-1 transcription factor subunit. | FOS like 1, AP-1 transcription factor subunit. | 0.944 |
| FOSB | FOSL2 | ENSBTAP00000010762 | ENSBTAP00000032838 | FosB proto-oncogene, AP-1 transcription factor subunit. | FOS like 2, AP-1 transcription factor subunit. | 0.961 |
| FOSB | JUN | ENSBTAP00000010762 | ENSBTAP00000005279 | FosB proto-oncogene, AP-1 transcription factor subunit. | Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28. Binds to the USP28 promoter; Belongs to the bZIP family. Jun subfamily. | 0.999 |
| FOSB | JUNB | ENSBTAP00000010762 | ENSBTAP00000015987 | FosB proto-oncogene, AP-1 transcription factor subunit. | Transcription factor jun-B; Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3' (By similarity); Belongs to the bZIP family. Jun subfamily. | 0.990 |
| FOSB | JUND | ENSBTAP00000010762 | ENSBTAP00000059607 | FosB proto-oncogene, AP-1 transcription factor subunit. | Transcription factor jun-D; Transcription factor binding AP-1 sites. Belongs to the bZIP family. Jun subfamily. | 0.999 |
| FOSL1 | FOS | ENSBTAP00000008136 | ENSBTAP00000005660 | FOS like 1, AP-1 transcription factor subunit. | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | 0.965 |
| FOSL1 | FOSB | ENSBTAP00000008136 | ENSBTAP00000010762 | FOS like 1, AP-1 transcription factor subunit. | FosB proto-oncogene, AP-1 transcription factor subunit. | 0.944 |
| FOSL1 | FOSL2 | ENSBTAP00000008136 | ENSBTAP00000032838 | FOS like 1, AP-1 transcription factor subunit. | FOS like 2, AP-1 transcription factor subunit. | 0.988 |
| FOSL1 | JUN | ENSBTAP00000008136 | ENSBTAP00000005279 | FOS like 1, AP-1 transcription factor subunit. | Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28. Binds to the USP28 promoter; Belongs to the bZIP family. Jun subfamily. | 0.999 |
| FOSL1 | JUNB | ENSBTAP00000008136 | ENSBTAP00000015987 | FOS like 1, AP-1 transcription factor subunit. | Transcription factor jun-B; Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3' (By similarity); Belongs to the bZIP family. Jun subfamily. | 0.974 |
| FOSL1 | JUND | ENSBTAP00000008136 | ENSBTAP00000059607 | FOS like 1, AP-1 transcription factor subunit. | Transcription factor jun-D; Transcription factor binding AP-1 sites. Belongs to the bZIP family. Jun subfamily. | 0.980 |
| FOSL2 | FOS | ENSBTAP00000032838 | ENSBTAP00000005660 | FOS like 2, AP-1 transcription factor subunit. | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | 0.947 |
| FOSL2 | FOSB | ENSBTAP00000032838 | ENSBTAP00000010762 | FOS like 2, AP-1 transcription factor subunit. | FosB proto-oncogene, AP-1 transcription factor subunit. | 0.961 |