STRINGSTRING
ZNF330 ZNF330 ADGRG2 ADGRG2 AQP1 AQP1 KATNA1 KATNA1 LOC282685 LOC282685 SLC26A9 SLC26A9 SLC4A1 SLC4A1 SLC9A2 SLC9A2 KLF5 KLF5 PCSK4 PCSK4 F1MQL2_BOVIN F1MQL2_BOVIN SCNN1A SCNN1A KLHL3 KLHL3 TBCCD1 TBCCD1 F1MY81_BOVIN F1MY81_BOVIN AQP12B AQP12B ANKMY1 ANKMY1 MORN5 MORN5 MORN3 MORN3 SLC9A3 SLC9A3 RDX RDX SPTB SPTB AQP10 AQP10 STK19 STK19 SPTBN4 SPTBN4 SPTBN2 SPTBN2 RSPH3 RSPH3 KATNBL1 KATNBL1 AHSP AHSP SPEF1 SPEF1 SPTBN1 SPTBN1 ARRDC3 ARRDC3 TRIM10 TRIM10 RBP5 RBP5 AQP2 AQP2 SLC22A14 SLC22A14 AQP3 AQP3 SLC9A8 SLC9A8 ADD2 ADD2 MORN1 MORN1 SLC5A2 SLC5A2 MIP MIP TTC1 TTC1 RHAG RHAG B4GALT2 B4GALT2 SCNN1B SCNN1B CNPPD1 CNPPD1 C7H5orf24 C7H5orf24 MSN MSN BSND BSND SGK3 SGK3 FAM71B FAM71B AQP9 AQP9 NEDD4 NEDD4 TMOD2 TMOD2 NDFIP2 NDFIP2 KEL KEL TMOD1 TMOD1 GYPC GYPC SLC4A3 SLC4A3 ARGLU1 ARGLU1 L2HGDH L2HGDH FADS3 FADS3 WWP1 WWP1 GOPC GOPC CETN4 CETN4 SCNN1D SCNN1D CA2 CA2 SLC4A8 SLC4A8 WNK4 WNK4 CNTD1 CNTD1 AQP11 AQP11 KLHL14 KLHL14 AQP7 AQP7 AQP8 AQP8 SLC9B1 SLC9B1 LOC784768 LOC784768 SLC4A9 SLC4A9 SLC9A6 SLC9A6 ABRAXAS2 ABRAXAS2 MORN2 MORN2 SLC9A4 SLC9A4 SLC26A3 SLC26A3 SLC9A3R1 SLC9A3R1 MKRN2OS MKRN2OS EPB42 EPB42 CHP1 CHP1 CCDC74B CCDC74B ARRDC5 ARRDC5 SLC26A7 SLC26A7 SLC12A1 SLC12A1 LOC524642 LOC524642 CLCNKA CLCNKA SLC9A1 SLC9A1 SLC9A5 SLC9A5 KATNAL1 KATNAL1 GYPA GYPA CFTR CFTR E1BLI3_BOVIN E1BLI3_BOVIN ANKRD65 ANKRD65 CCER1 CCER1 SLC26A6 SLC26A6 SPTA1 SPTA1 RBM12 RBM12 ANK3 ANK3 SLC9C1 SLC9C1 FAM189B FAM189B DMTN DMTN GYPB GYPB LRRC63 LRRC63 SLC9A3R2 SLC9A3R2 EPB41 EPB41 SLC28A1 SLC28A1 CYB5D1 CYB5D1 PPP1R21 PPP1R21 SPTAN1 SPTAN1 ENOX2 ENOX2 EZR EZR WWP2 WWP2 TMOD3 TMOD3 KATNB1 KATNB1 SLC4A4 SLC4A4 UMOD UMOD KLHL2 KLHL2 ENSBTAP00000061807 ENSBTAP00000061807 D2HGDH D2HGDH ENSBTAP00000063139 ENSBTAP00000063139 SCNN1G SCNN1G SLC4A2 SLC4A2 SGK1 SGK1 NDUFAF8 NDUFAF8 ENSBTAP00000065053 ENSBTAP00000065053 AQP5 AQP5 ENSBTAP00000065605 ENSBTAP00000065605 KCNJ1 KCNJ1 LOC112445029 LOC112445029 ENSBTAP00000066293 ENSBTAP00000066293 ENSBTAP00000066891 ENSBTAP00000066891 STK39 STK39 SLC26A11 SLC26A11 TMEM52B TMEM52B SLC12A3 SLC12A3 NEDD4L NEDD4L VILL VILL ANO1 ANO1 SGK2 SGK2 ENSBTAP00000068684 ENSBTAP00000068684 NDFIP1 NDFIP1 ENSBTAP00000069125 ENSBTAP00000069125 ENSBTAP00000069149 ENSBTAP00000069149 CALM1 CALM1 ADD3 ADD3 MOB2 MOB2 TSC22D3 TSC22D3 WNK1 WNK1 ARRDC1 ARRDC1 PCIF1 PCIF1 N4BP1 N4BP1 ENSBTAP00000073146 ENSBTAP00000073146 DTNA DTNA SLC34A1 SLC34A1 ADD1 ADD1 ANK2 ANK2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ZNF330Zinc finger protein 330. (320 aa)
ADGRG2Adhesion G protein-coupled receptor G2; Belongs to the G-protein coupled receptor 2 family. (964 aa)
AQP1Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. (271 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
LOC282685Rhesus-like protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (417 aa)
SLC26A9Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (805 aa)
SLC4A1Anion exchange protein. (945 aa)
SLC9A2Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (810 aa)
KLF5Kruppel like factor 5. (454 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (752 aa)
F1MQL2_BOVINUncharacterized protein. (1074 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception. Belongs to the amilori [...] (650 aa)
KLHL3Kelch-like protein 3; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation (By similarity). The BCR(KLHL3) complex also mediates ubiquitination and degradation of CLDN8, a tight-junction protein required for paracellular chloride transport in the kidney (By similarity). (587 aa)
TBCCD1TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration; Belongs to the TBCC family. (557 aa)
F1MY81_BOVINANK_REP_REGION domain-containing protein. (502 aa)
AQP12BAquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (311 aa)
ANKMY1Ankyrin repeat and MYND domain containing 1. (229 aa)
MORN5MORN repeat-containing protein 5. (193 aa)
MORN3MORN repeat-containing protein 3. (241 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (835 aa)
RDXRadixin; Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane. (583 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2331 aa)
AQP10Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. (277 aa)
STK19Serine/threonine kinase 19. (169 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2615 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2394 aa)
RSPH3Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia (By similarity). (606 aa)
KATNBL1Katanin regulatory subunit B1 like 1. (304 aa)
AHSPAlpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation (By similarity). (92 aa)
SPEF1Sperm flagellar protein 1; Microtubule-associated protein involved in the stabilization of microtubules along the axis of migration during radial intercalation. Promotes the establishment and stabilization of an axis of microtubules required for the active migration of cells into the outer epithelium (By similarity). Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock (By similarity). (236 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2363 aa)
ARRDC3Arrestin domain-containing protein 3; Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein- coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes. (414 aa)
TRIM10Tripartite motif-containing protein 10; Seems to play an important role in erythropoiesis. Belongs to the TRIM/RBCC family. (489 aa)
RBP5Retinol-binding protein 5; Intracellular transport of retinol. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
AQP2Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SLC22A14Solute carrier family 22 member 14. (576 aa)
AQP3Aquaporin-3; Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an [...] (292 aa)
SLC9A8Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (577 aa)
ADD2Adducin 2. (724 aa)
MORN1MORN repeat containing 1. (476 aa)
SLC5A2Solute carrier family 5 member 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (673 aa)
MIPLens fiber major intrinsic protein; Water channel. Channel activity is down- regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity). Plays a role in cell- to-cell adhesion and facilitates gap junction coupling. Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
TTC1Tetratricopeptide repeat protein 1. (292 aa)
RHAGAmmonium transporter Rh type A; May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Involved in ammonia transport across the erythrocyte membrane. Seems to act as a monovalent cation transport. (426 aa)
B4GALT2Beta-1,4-galactosyltransferase 2. (397 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] (641 aa)
CNPPD1Protein CNPPD1. (371 aa)
C7H5orf24UPF0461 protein C5orf24 homolog; Belongs to the UPF0461 family. (188 aa)
MSNMoesin; Ezrin-radixin-moesin (ERM) family protein that connects the actin cytoskeleton to the plasma membrane and thereby regulates the structure and function of specific domains of the cell cortex. Tethers actin filaments by oscillating between a resting and an activated state providing transient interactions between moesin and the actin cytoskeleton. Once phosphorylated on its C-terminal threonine, moesin is activated leading to interaction with F-actin and cytoskeletal rearrangement. These rearrangements regulate many cellular processes, including cell shape determination, membrane [...] (577 aa)
BSNDBarttin CLCNK type accessory beta subunit. (319 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (490 aa)
FAM71BFamily with sequence similarity 71 member B. (587 aa)
AQP9Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1321 aa)
TMOD2Tropomodulin 2. (351 aa)
NDFIP2Nedd4 family interacting protein 2. (336 aa)
KELKell metallo-endopeptidase. (721 aa)
TMOD1Tropomodulin-1; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus (By similarity). (359 aa)
GYPCGlycophorin C. (109 aa)
SLC4A3Anion exchange protein. (1226 aa)
ARGLU1Arginine and glutamate-rich protein 1; Belongs to the UPF0430 family. (273 aa)
L2HGDHL-2-hydroxyglutarate dehydrogenase, mitochondrial. (463 aa)
FADS3Fatty acid desaturase 3; Acts as a methyl-end fatty acyl coenzyme A (CoA) desaturase that introduces a cis double bond between the preexisting double bond and the terminal methyl group of the fatty acyl chain. Desaturates (11E)-octadecenoate (trans-vaccenoate) at carbon 13 to generate (11E,13Z)-octadecadienoate, likely participating in the biohydrogenation pathway of linoleic acid (LA) (18:2n-6). (443 aa)
WWP1E3 ubiquitin-protein ligase. (921 aa)
GOPCGolgi associated PDZ and coiled-coil motif containing. (463 aa)
CETN4Centrin 4. (166 aa)
SCNN1DSodium channel epithelial 1 delta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (651 aa)
CA2Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. (260 aa)
SLC4A8Anion exchange protein. (1092 aa)
WNK4WNK lysine deficient protein kinase 4. (1246 aa)
CNTD1Cyclin N-terminal domain containing 1. (339 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
KLHL14Kelch like family member 14. (626 aa)
AQP7Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (317 aa)
AQP8Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
SLC9B1Solute carrier family 9 member B1. (513 aa)
LOC784768Calcium-activated chloride channel regulator 1; May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC; Belongs to the CLCR family. (903 aa)
SLC4A9Anion exchange protein. (955 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (724 aa)
ABRAXAS2BRISC complex subunit Abraxas 2; Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked polyubiquitin, leaving the last ubiquitin chain attached to its substrates. May act as a central scaffold protein that assembles the various components of the BRISC complex and retains them in the cytoplasm (By similarity). Plays a role in regulating the onset of apoptosis via its role in modulating 'Lys- 63'-linked ubiquitination of target proteins (By similarity). Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via i [...] (415 aa)
MORN2MORN repeat-containing protein 2. (191 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (760 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatoz [...] (368 aa)
MKRN2OSMKRN2 opposite strand. (230 aa)
EPB42Erythrocyte membrane protein band 4.2; Band 4.2 probably plays an important role in the regulation of erythrocyte shape and mechanical properties. The major membrane binding for band 4.2 is the cytoplasmic domain of the erythrocyte anion transporter, band 3 (By similarity); Belongs to the transglutaminase superfamily. Transglutaminase family. (687 aa)
CHP1Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane- type Na(+)/H(+) ex [...] (195 aa)
CCDC74BCCDC74_C domain-containing protein. (274 aa)
ARRDC5Arrestin domain-containing protein 5; Belongs to the arrestin family. (332 aa)
SLC26A7Anion exchange transporter. (655 aa)
SLC12A1Solute carrier family 12 member 1. (1099 aa)
LOC524642GP-PDE domain-containing protein. (613 aa)
CLCNKAChloride channel protein. (687 aa)
SLC9A1Sodium/hydrogen exchanger 1; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. (818 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (900 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
GYPAGlycophorin A. (99 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1481 aa)
E1BLI3_BOVINULP_PROTEASE domain-containing protein. (221 aa)
ANKRD65Ankyrin repeat domain-containing protein 65. (395 aa)
CCER1Coiled-coil domain-containing glutamate-rich protein 1. (415 aa)
SLC26A6Solute carrier family 26, member 6. (763 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2411 aa)
RBM12RNA binding motif protein 12. (953 aa)
ANK3Ankyrin 3. (1116 aa)
SLC9C1Solute carrier family 9 member C1. (1129 aa)
FAM189BFamily with sequence similarity 189 member B. (669 aa)
DMTNDematin; Membrane-cytoskeleton-associated protein with F-actin-binding activity that induces F-actin bundles formation and stabilization. Its F-actin-bundling activity is reversibly regulated upon its phosphorylation by the cAMP-dependent protein kinase A (PKA). Binds to the erythrocyte membrane glucose transporter-1 SLC2A1/GLUT1, and hence stabilizes and attaches the spectrin-actin network to the erythrocytic plasma membrane. Plays a role in maintaining the functional integrity of PKA-activated erythrocyte shape and the membrane mechanical properties. Plays also a role as a modulator [...] (467 aa)
GYPBGlycophorin B variant 1. (86 aa)
LRRC63Leucine rich repeat containing 63. (568 aa)
SLC9A3R2Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (337 aa)
EPB41Protein 4.1; Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase. (784 aa)
SLC28A1Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (702 aa)
CYB5D1Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (228 aa)
PPP1R21Protein phosphatase 1 regulatory subunit 21. (784 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2489 aa)
ENOX2Ecto-NOX disulfide-thiol exchanger 2. (581 aa)
EZREzrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). (670 aa)
WWP2E3 ubiquitin-protein ligase. (877 aa)
TMOD3Uncharacterized protein. (340 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (689 aa)
SLC4A4Electrogenic sodium bicarbonate cotransporter 1; Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH; Belongs to the anion exchanger (TC 2.A.31) family. (1136 aa)
UMODUromodulin, secreted form; [Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. (647 aa)
KLHL2Kelch like family member 2. (593 aa)
ENSBTAP00000061807Uncharacterized protein. (271 aa)
D2HGDHD-2-hydroxyglutarate dehydrogenase, mitochondrial; Catalyzes the oxidation of D-2-hydroxyglutarate to alpha- ketoglutarate. (544 aa)
ENSBTAP00000063139Uncharacterized protein. (173 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. (652 aa)
SLC4A2Anion exchange protein. (1302 aa)
SGK1Serine/threonine-protein kinase Sgk1; Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription factors, neuronal excitability, cell growth, proliferation, survival, migration and apoptosis. Plays an important role in cellular stress response. Contributes to regulation of renal Na(+) retention, renal K(+) elimination, salt appetite, gastric acid secretion, intestinal Na(+)/H(+) exchange and nutrient transport, insulin-dependent salt sensitivity of blood pressure, salt sensitivity of peri [...] (526 aa)
NDUFAF8NADH:ubiquinone oxidoreductase complex assembly factor 8. (74 aa)
ENSBTAP00000065053ANK_REP_REGION domain-containing protein. (217 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (555 aa)
ENSBTAP00000065605Uncharacterized protein. (75 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (385 aa)
LOC112445029Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (671 aa)
ENSBTAP00000066293Uncharacterized protein. (138 aa)
ENSBTAP00000066891Uncharacterized protein. (74 aa)
STK39Serine/threonine kinase 39. (537 aa)
SLC26A11Sodium-independent sulfate anion transporter; Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (602 aa)
TMEM52BTransmembrane protein 52B. (182 aa)
SLC12A3Solute carrier family 12 member 3. (1093 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1255 aa)
VILLVillin like. (889 aa)
ANO1Anoctamin. (1040 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (388 aa)
ENSBTAP00000068684Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (340 aa)
NDFIP1Nedd4 family interacting protein 1. (252 aa)
ENSBTAP00000069125ULP_PROTEASE domain-containing protein. (214 aa)
ENSBTAP00000069149Uncharacterized protein. (777 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (150 aa)
ADD3Adducin 3. (706 aa)
MOB2MOB kinase activator 2. (601 aa)
TSC22D3Uncharacterized protein. (423 aa)
WNK1WNK lysine deficient protein kinase 1. (2832 aa)
ARRDC1Arrestin domain containing 1. (431 aa)
PCIF1PDX1 C-terminal inhibiting factor 1. (702 aa)
N4BP1NEDD4 binding protein 1. (897 aa)
ENSBTAP00000073146ANK_REP_REGION domain-containing protein. (561 aa)
DTNADystrobrevin. (743 aa)
SLC34A1Solute carrier family 34 member 1. (671 aa)
ADD1Adducin 1. (769 aa)
ANK2ANK_REP_REGION domain-containing protein. (471 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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