STRINGSTRING
LRRN4 LRRN4 RFX4 RFX4 MSLN MSLN SVEP1 SVEP1 PI16 PI16 LOC100300091 LOC100300091 HIGD1B HIGD1B TCF21 TCF21 UPK3B UPK3B C23H6orf89 C23H6orf89 F1N6T9_BOVIN F1N6T9_BOVIN PDZD2 PDZD2 MUC16 MUC16 SEMA3D SEMA3D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRN4Leucine rich repeat neuronal 4. (747 aa)
RFX4Regulatory factor X4. (641 aa)
MSLNMSLN protein. (403 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3227 aa)
PI16Peptidase inhibitor 16; May inhibit cardiomyocyte growth. Belongs to the CRISP family. (464 aa)
LOC100300091Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (171 aa)
HIGD1BHIG1 hypoxia inducible domain family member 1B. (99 aa)
TCF21Transcription factor 21; Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. May play a role in the specification or differentiation of one or more subsets of epicardial cell types (By similarity). (179 aa)
UPK3BUroplakin-3b; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). Belongs to the uroplakin-3 family. (279 aa)
C23H6orf89Chromosome 23 C6orf89 homolog. (348 aa)
F1N6T9_BOVINUncharacterized protein. (142 aa)
PDZD2PDZ domain containing 2. (2805 aa)
MUC16SEA domain-containing protein. (228 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (776 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
Server load: low (22%) [HD]