STRINGSTRING
SLC26A10 SLC26A10 SLC12A4 SLC12A4 SLC45A2 SLC45A2 SLC1A3 SLC1A3 SLC28A3 SLC28A3 ATP1A3 ATP1A3 SLC22A11 SLC22A11 SLC2A12 SLC2A12 SLC1A1 SLC1A1 SLC39A14 SLC39A14 SLC22A9 SLC22A9 SLCO1C1 SLCO1C1 SLC35D2 SLC35D2 LETM1 LETM1 SLC10A5 SLC10A5 SLC36A2 SLC36A2 SLC9B1 SLC9B1 SLC16A13 SLC16A13 SLC4A9 SLC4A9 SLC5A12 SLC5A12 SLCO1B3 SLCO1B3 SLC15A3 SLC15A3 LOC531152 LOC531152 SLC9A6 SLC9A6 SLC5A6 SLC5A6 SLC9A4 SLC9A4 SLC26A3 SLC26A3 SLC26A4 SLC26A4 SLC6A7 SLC6A7 SLC25A11 SLC25A11 SLC46A1 SLC46A1 SLC17A3 SLC17A3 SLC6A11 SLC6A11 SLCO6A1 SLCO6A1 SLC15A5 SLC15A5 SLC37A1 SLC37A1 MFSD2B MFSD2B SLC41A3 SLC41A3 SLC9A9 SLC9A9 SLC35E2 SLC35E2 SLC35E3 SLC35E3 SLC26A7 SLC26A7 SLC18A1 SLC18A1 CDH17 CDH17 SLC12A1 SLC12A1 SLCO5A1 SLCO5A1 SLC9C2 SLC9C2 SLC9A1 SLC9A1 SLC9A5 SLC9A5 LOC616319 LOC616319 SLC26A6 SLC26A6 F1N3X5_BOVIN F1N3X5_BOVIN SLC24A2 SLC24A2 SLC9C1 SLC9C1 SLC2A13 SLC2A13 SLC4A7 SLC4A7 LOC785907 LOC785907 ENSBTAP00000054367 ENSBTAP00000054367 SLC25A6 SLC25A6 SLC6A19 SLC6A19 LOC519202 LOC519202 SLC32A1 SLC32A1 CLCN4 CLCN4 SLC36A3 SLC36A3 SLC28A1 SLC28A1 SLC25A1 SLC25A1 SLC19A1 SLC19A1 SLC25A13 SLC25A13 SLC37A4 SLC37A4 SLC6A6 SLC6A6 SLC13A1 SLC13A1 SLC6A12 SLC6A12 CTNS CTNS SLC25A5 SLC25A5 SLC8A3 SLC8A3 SLC47A2 SLC47A2 SLC4A4 SLC4A4 ENSBTAP00000060800 ENSBTAP00000060800 SLC6A15 SLC6A15 MFSD3 MFSD3 ENSBTAP00000061480 ENSBTAP00000061480 SLC24A1 SLC24A1 SLC8B1 SLC8B1 SLC4A2 SLC4A2 ENSBTAP00000063388 ENSBTAP00000063388 SLC5A9 SLC5A9 SLC37A2 SLC37A2 SLC5A1 SLC5A1 CLCN3 CLCN3 SLC4A10 SLC4A10 SLC34A3 SLC34A3 SLC6A2 SLC6A2 SLC35C2 SLC35C2 SLC4A11 SLC4A11 SLC15A4 SLC15A4 LOC112445029 LOC112445029 SLC45A4 SLC45A4 SLC26A11 SLC26A11 ENSBTAP00000067263 ENSBTAP00000067263 SLC6A4 SLC6A4 SLC12A3 SLC12A3 SLC25A12 SLC25A12 SLC5A10 SLC5A10 SLC6A20 SLC6A20 TMEM241 TMEM241 ENSBTAP00000068684 ENSBTAP00000068684 SLC34A2 SLC34A2 SLC9B2 SLC9B2 SLC35C1 SLC35C1 SLC12A7 SLC12A7 SLC23A2 SLC23A2 ENSBTAP00000072448 ENSBTAP00000072448 SLC2A10 SLC2A10 SLC6A9 SLC6A9 SLC6A14 SLC6A14 SLC35B1 SLC35B1 SLC34A1 SLC34A1 SLC47A1 SLC47A1 SLC1A2 SLC1A2 SLC10A7 SLC10A7 SLC7A5 SLC7A5 SLC25A10 SLC25A10 SLC13A3 SLC13A3 SLC17A8 SLC17A8 SLC25A22 SLC25A22 SLCO2A1 SLCO2A1 SLC26A9 SLC26A9 SLC45A1 SLC45A1 SLC15A2 SLC15A2 CLCN5 CLCN5 SLC4A1 SLC4A1 SLCO3A1 SLCO3A1 SLC9A2 SLC9A2 SLC10A1 SLC10A1 SLC6A17 SLC6A17 SLC35E4 SLC35E4 SLC16A2 SLC16A2 SLC17A2 SLC17A2 SLCO1A2 SLCO1A2 SLC9A7 SLC9A7 SLC12A9 SLC12A9 SLC5A11 SLC5A11 MCU MCU SLC5A7 SLC5A7 SLC15A1 SLC15A1 SLC9A3 SLC9A3 SLC13A5 SLC13A5 SLC18A2 SLC18A2 SLC24A5 SLC24A5 SLC4A5 SLC4A5 SLC10A4 SLC10A4 SLC35E1 SLC35E1 SLC41A1 SLC41A1 SLC35D1 SLC35D1 SLC39A8 SLC39A8 SLC6A1 SLC6A1 ADGRV1 ADGRV1 SLC17A6 SLC17A6 SLC24A4 SLC24A4 SLC26A1 SLC26A1 SLC17A7 SLC17A7 SLC7A8 SLC7A8 SLC45A3 SLC45A3 SLC1A4 SLC1A4 SLC20A1 SLC20A1 SLC5A4 SLC5A4 SLC23A1 SLC23A1 LOC785933 LOC785933 LOC515755 LOC515755 SLC9A8 SLC9A8 SLC2A4 SLC2A4 SLC16A10 SLC16A10 SLC26A5 SLC26A5 SLC12A2 SLC12A2 SLC6A8 SLC6A8 SLC22A4 SLC22A4 SLC5A2 SLC5A2 SLC8A2 SLC8A2 SLC38A2 SLC38A2 SLC5A8 SLC5A8 SLC25A15 SLC25A15 SLC24A3 SLC24A3 SLC1A7 SLC1A7 SLC6A18 SLC6A18 SLC25A31 SLC25A31 SLC25A3 SLC25A3 SLC6A16 SLC6A16 MFSD2A MFSD2A SLC25A4 SLC25A4 ANKH ANKH SLC1A6 SLC1A6 SLC1A5 SLC1A5 SLC22A6 SLC22A6 SLC22A8 SLC22A8 SLC12A8 SLC12A8 SLC35A1 SLC35A1 SLC12A5 SLC12A5 SLC6A5 SLC6A5 SLC33A1 SLC33A1 SLC10A3 SLC10A3 SLC6A13 SLC6A13 SLC26A2 SLC26A2 SLC20A2 SLC20A2 SLC4A3 SLC4A3 MFSD12 MFSD12 SLC16A1 SLC16A1 SLC11A1 SLC11A1 SLCO2B1 SLCO2B1 TMCO3 TMCO3 SLC5A5 SLC5A5 SLC6A3 SLC6A3 CLCN7 CLCN7 SLC10A2 SLC10A2 SLC36A1 SLC36A1 SLC12A6 SLC12A6 SLC25A14 SLC25A14 SLC28A2 SLC28A2 SLCO4C1 SLCO4C1 SLCO4A1 SLCO4A1 SLC25A30 SLC25A30 SLC35D3 SLC35D3 SLC10A6 SLC10A6 SLC8A1 SLC8A1 SLC26A8 SLC26A8 SLC4A8 SLC4A8
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SLC26A10STAS domain-containing protein. (683 aa)
SLC12A4Solute carrier family 12 member 4. (1086 aa)
SLC45A2Solute carrier family 45 member 2. (576 aa)
SLC1A3Excitatory amino acid transporter 1; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (By similarity). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity). (542 aa)
SLC28A3Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (697 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (988 aa)
SLC22A11Solute carrier family 22 member 11. (525 aa)
SLC2A12Solute carrier family 2, facilitated glucose transporter member 12; Insulin-independent facilitative glucose transporter. (621 aa)
SLC1A1Excitatory amino acid transporter 3; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D- aspartate. Can also transport L-cysteine (By similarity). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter- transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (By similarity). Plays an important role in L-glu [...] (524 aa)
SLC39A14Zinc transporter ZIP14; Broad-scope metal ion transporter with a preference for zinc uptake. Also mediates cellular uptake of nontransferrin-bound iron. (490 aa)
SLC22A9Solute carrier family 22 member 9; Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons- containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes (By similarity); Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. (552 aa)
SLCO1C1Solute carrier organic anion transporter family member. (712 aa)
SLC35D2UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter. (338 aa)
LETM1Mitochondrial proton/calcium exchanger protein; Mitochondrial proton/calcium antiporter that mediates proton- dependent calcium efflux from mitochondrion (By similarity). Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (By similarity). Required for the maintenance of the tubular shape and cristae organization (By similarity). In contrast to SLC8B1/NCLX, does not constitute the major factor for mitochondrial calcium extrusion (By similarity); Belongs to the LETM1 family. (786 aa)
SLC10A5Solute carrier family 10 member 5. (438 aa)
SLC36A2Solute carrier family 36 member 2. (482 aa)
SLC9B1Solute carrier family 9 member B1. (513 aa)
SLC16A13Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. (426 aa)
SLC4A9Anion exchange protein. (955 aa)
SLC5A12Sodium-coupled monocarboxylate transporter 2; Acts as an electroneutral and low-affinity sodium (Na(+))- dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina. Mediates electroneutral uptake of lactate, with a stoichiomet [...] (617 aa)
SLCO1B3Solute carrier organic anion transporter family member. (689 aa)
SLC15A3Solute carrier family 15 member 3. (581 aa)
LOC531152Similar to solute carrier family 5 (Sodium/glucose cotransporter), member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (225 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (724 aa)
SLC5A6Solute carrier family 5 member 6; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (638 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (760 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (781 aa)
SLC6A7Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (636 aa)
SLC25A11Mitochondrial 2-oxoglutarate/malate carrier protein; Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae. Involved in the regulation of apoptosis; Belongs to the mitochondrial carrier (TC 2.A.29) [...] (314 aa)
SLC46A1Proton-coupled folate transporter; Has been shown to act both as an intestinal proton-coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial cells. The iron is then released from heme and may be transported into the bloodstream. Dietary heme iron is an important nutritional source of iron. Shows a higher affinity for folate than heme. Belongs to the major facilitator superfamily. SLC46A family. (459 aa)
SLC17A3Solute carrier family 17 (Sodium phosphate), member 3. (493 aa)
SLC6A11Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
SLCO6A1Solute carrier organic anion transporter family member. (752 aa)
SLC15A5Solute carrier family 15 member 5. (571 aa)
SLC37A1Solute carrier family 37 member 1. (503 aa)
MFSD2BMajor facilitator superfamily domain containing 2B. (490 aa)
SLC41A3Solute carrier family 41 member 3. (484 aa)
SLC9A9Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (640 aa)
SLC35E2TPT domain-containing protein. (405 aa)
SLC35E3Solute carrier family 35 member E3; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily. (313 aa)
SLC26A7Anion exchange transporter. (655 aa)
SLC18A1Solute carrier family 18 member A1. (523 aa)
CDH17CDH17 protein. (832 aa)
SLC12A1Solute carrier family 12 member 1. (1099 aa)
SLCO5A1Solute carrier organic anion transporter family member. (846 aa)
SLC9C2Cyclic nucleotide-binding domain-containing protein. (378 aa)
SLC9A1Sodium/hydrogen exchanger 1; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. (818 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (900 aa)
LOC616319LOC616319 protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (330 aa)
SLC26A6Solute carrier family 26, member 6. (763 aa)
F1N3X5_BOVINUncharacterized protein. (112 aa)
SLC24A2Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (660 aa)
SLC9C1Solute carrier family 9 member C1. (1129 aa)
SLC2A13Solute carrier family 2 member 13; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (648 aa)
SLC4A7Anion exchange protein. (1218 aa)
LOC785907Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (693 aa)
ENSBTAP00000054367Uncharacterized protein. (196 aa)
SLC25A6ADP/ATP translocase 3, N-terminally processed; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (By similarity). (298 aa)
SLC6A19Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (634 aa)
LOC519202MFS domain-containing protein. (538 aa)
SLC32A1Solute carrier family 32 member 1. (526 aa)
CLCN4Chloride channel protein. (782 aa)
SLC36A3Solute carrier family 36 member 3. (475 aa)
SLC28A1Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (702 aa)
SLC25A1Tricarboxylate transport protein, mitochondrial; Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Required for proper neuromuscular junction formation. Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa)
SLC19A1Solute carrier family 19 member 1. (614 aa)
SLC25A13Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (679 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
SLC6A6Sodium- and chloride-dependent taurine transporter; Sodium-dependent taurine and beta-alanine transporter. (722 aa)
SLC13A1Solute carrier family 13 member 1. (658 aa)
SLC6A12Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (656 aa)
CTNSCystinosin; Cystine/H(+) symporter thought to transport cystine out of lysosomes. Plays an important role in melanin synthesis, possibly by preventing melanosome acidification and subsequent degradation of tyrosinase TYR; Belongs to the cystinosin family. (377 aa)
SLC25A5ADP/ATP translocase 2, N-terminally processed; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (By similarity). (299 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
SLC47A2Multidrug and toxin extrusion protein; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (630 aa)
SLC4A4Electrogenic sodium bicarbonate cotransporter 1; Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH; Belongs to the anion exchanger (TC 2.A.31) family. (1136 aa)
ENSBTAP00000060800Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (304 aa)
SLC6A15Sodium-dependent neutral amino acid transporter B(0)AT2; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for methionine and for the branched- chain amino acids, particularly leucine, valine and isoleucine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily. (729 aa)
MFSD3Major facilitator superfamily domain containing 3. (414 aa)
ENSBTAP00000061480AA_permease domain-containing protein. (229 aa)
SLC24A1Sodium/potassium/calcium exchanger 1; Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (By similarity). Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily. (1215 aa)
SLC8B1Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (584 aa)
SLC4A2Anion exchange protein. (1302 aa)
ENSBTAP00000063388Uncharacterized protein. (437 aa)
SLC5A9Solute carrier family 5 member 9; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (681 aa)
SLC37A2Glucose-6-phosphate exchanger SLC37A2; Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels. (505 aa)
SLC5A1Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (664 aa)
CLCN3Chloride channel protein. (872 aa)
SLC4A10Sodium-driven chloride bicarbonate exchanger; Sodium/bicarbonate cotransporter which plays an important role in regulating intracellular pH (By similarity). Has been shown to act as a sodium/bicarbonate cotransporter in exchange for intracellular chloride (By similarity). Has also been shown to act as a sodium/biocarbonate cotransporter which does not couple net influx of bicarbonate to net efflux of chloride, with the observed chloride efflux being due to chloride self-exchange (By similarity). Controls neuronal pH and may contribute to the secretion of cerebrospinal fluid (By similar [...] (1117 aa)
SLC34A3Solute carrier family 34 member 3. (765 aa)
SLC6A2Sodium-dependent noradrenaline transporter; Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals. (673 aa)
SLC35C2Solute carrier family 35 member C2. (365 aa)
SLC4A11Solute carrier family 4 member 11. (906 aa)
SLC15A4Solute carrier family 15 member 4; Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides (By similarity); Belongs to the PTR2/POT transporter (TC 2.A.17) family. (566 aa)
LOC112445029Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (671 aa)
SLC45A4Solute carrier family 45 member 4. (814 aa)
SLC26A11Sodium-independent sulfate anion transporter; Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (602 aa)
ENSBTAP00000067263Uncharacterized protein. (393 aa)
SLC6A4Sodium-dependent serotonin transporter; Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner. (630 aa)
SLC12A3Solute carrier family 12 member 3. (1093 aa)
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (712 aa)
SLC5A10Sodium/glucose cotransporter 5; High capacity transporter for mannose and fructose and, to a lesser extent, glucose, AMG, and galactose. (645 aa)
SLC6A20Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (592 aa)
TMEM241Transmembrane protein 241. (250 aa)
ENSBTAP00000068684Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (340 aa)
SLC34A2Sodium-dependent phosphate transport protein 2B; May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli (By similarity). (711 aa)
SLC9B2Solute carrier family 9 member B2. (535 aa)
SLC35C1GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily. (364 aa)
SLC12A7Solute carrier family 12 member 7. (901 aa)
SLC23A2Solute carrier family 23 member 2. (650 aa)
ENSBTAP00000072448Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (218 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (570 aa)
SLC6A9Sodium- and chloride-dependent glycine transporter 1; Terminates the action of glycine by its high affinity sodium- dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission (By similarity). (735 aa)
SLC6A14Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (682 aa)
SLC35B1Solute carrier family 35 member B1; Probable sugar transporter. (355 aa)
SLC34A1Solute carrier family 34 member 1. (671 aa)
SLC47A1Uncharacterized protein. (300 aa)
SLC1A2Amino acid transporter. (595 aa)
SLC10A7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (340 aa)
SLC7A5Solute carrier family 7 member 5. (617 aa)
SLC25A10Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (287 aa)
SLC13A3Solute carrier family 13 (Sodium-dependent dicarboxylate transporter), member 3. (602 aa)
SLC17A8Solute carrier family 17 member 8. (588 aa)
SLC25A22Mitochondrial glutamate carrier 1; Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+) (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family. (322 aa)
SLCO2A1Solute carrier organic anion transporter family member. (644 aa)
SLC26A9Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (805 aa)
SLC45A1Solute carrier family 45 member 1. (754 aa)
SLC15A2Uncharacterized protein. (729 aa)
CLCN5Chloride channel protein. (816 aa)
SLC4A1Anion exchange protein. (945 aa)
SLCO3A1Solute carrier organic anion transporter family member 3A1; Mediates the Na(+)-independent transport of organic anions. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin. (710 aa)
SLC9A2Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (810 aa)
SLC10A1Solute carrier family 10 (Sodium/bile acid cotransporter family), member 1. (370 aa)
SLC6A17Sodium-dependent neutral amino acid transporter SLC6A17; Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity); Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A17 subfamily. (727 aa)
SLC35E4Solute carrier family 35 member E4. (350 aa)
SLC16A2Solute carrier family 16 member 2. (604 aa)
SLC17A2Sodium-dependent phosphate transport protein 3; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane (By similarity). (479 aa)
SLCO1A2Solute carrier organic anion transporter family member. (666 aa)
SLC9A7Solute carrier family 9 member A7. (690 aa)
SLC12A9Solute carrier family 12 member 9. (914 aa)
SLC5A11Sodium/myo-inositol cotransporter 2; Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D- chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney; Belongs to the sodium:solute symporter (SSF) (TC 2 [...] (673 aa)
MCUMitochondrial calcium uniporter. (351 aa)
SLC5A7Solute carrier family 5 (Choline transporter), member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
SLC15A1Solute carrier family 15 member 1. (706 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (835 aa)
SLC13A5Solute carrier family 13 member 5. (566 aa)
SLC18A2Synaptic vesicular amine transporter; Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis. (517 aa)
SLC24A5Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (501 aa)
SLC4A5Anion exchange protein. (1036 aa)
SLC10A4Solute carrier family 10 (Sodium/bile acid cotransporter family), member 4. (448 aa)
SLC35E1Solute carrier family 35 member E1. (412 aa)
SLC41A1Solute carrier family 41 member 1. (514 aa)
SLC35D1UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-GlcNAc, the donor substrate, and thus be involved in growth factor signaling (By similarity); Belongs to the TPT transporter family. SLC35D subfamily. (355 aa)
SLC39A8Solute carrier family 39 member 8. (461 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6307 aa)
SLC17A6Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate (By similarity). Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. (582 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (603 aa)
SLC26A1Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (873 aa)
SLC17A7Vesicular glutamate transporter 1; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate (By similarity). (560 aa)
SLC7A8Solute carrier family 7 member 8. (528 aa)
SLC45A3Solute carrier family 45 member 3. (550 aa)
SLC1A4Neutral amino acid transporter A; Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A4 subfamily. (530 aa)
SLC20A1Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (681 aa)
SLC5A4Solute carrier family 5 member 4; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (660 aa)
SLC23A1Solute carrier family 23 member 1. (604 aa)
LOC785933Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (715 aa)
LOC515755Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (757 aa)
SLC9A8Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (577 aa)
SLC2A4Solute carrier family 2, facilitated glucose transporter member 4; Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell. (509 aa)
SLC16A10Solute carrier family 16 member 10. (515 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (741 aa)
SLC12A2Solute carrier family 12 member 2. (1201 aa)
SLC6A8Sodium- and chloride-dependent creatine transporter 1; Required for the uptake of creatine. Plays an important role in supplying creatine to the brain via the blood-brain barrier (By similarity); Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily. (635 aa)
SLC22A4Solute carrier family 22 member 4. (553 aa)
SLC5A2Solute carrier family 5 member 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (673 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
SLC38A2Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta (By similarity). (506 aa)
SLC5A8Sodium-dependent monocarboxylate cotransporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (611 aa)
SLC25A15Solute carrier family 25 (Mitochondrial carrier; ornithine transporter) member 15; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa)
SLC24A3Solute carrier family 24 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (594 aa)
SLC1A7Amino acid transporter. (560 aa)
SLC6A18Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (616 aa)
SLC25A31ADP/ATP translocase 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility (By similarity). (323 aa)
SLC25A3Phosphate carrier protein, mitochondrial; Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP); Belongs to the mitochondrial carrier (TC 2.A.29) family. (362 aa)
SLC6A16Solute carrier family 6 member 16. (761 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (454 aa)
SLC25A4ADP/ATP translocase 1; Involved in mitochondrial ADP/ATP transport. Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. (298 aa)
ANKHANKH inorganic pyrophosphate transport regulator. (492 aa)
SLC1A6Amino acid transporter. (564 aa)
SLC1A5Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. (539 aa)
SLC22A6Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of p-aminohippurate (PAH), 2,3- dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2- phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido- 3-'deoxy [...] (549 aa)
SLC22A8Solute carrier family 22 member 8. (543 aa)
SLC12A8Solute carrier family 12 member 8. (714 aa)
SLC35A1Solute carrier family 35 (CMP-sialic acid transporter), member A1. (337 aa)
SLC12A5Solute carrier family 12 member 5. (1116 aa)
SLC6A5Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (798 aa)
SLC33A1Solute carrier family 33 (Acetyl-CoA transporter), member 1. (550 aa)
SLC10A3P3 protein; The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (477 aa)
SLC6A13Sodium- and chloride-dependent GABA transporter 2; Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport (By similarity). Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily. (602 aa)
SLC26A2Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (734 aa)
SLC20A2Sodium-dependent phosphate transporter 2; Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not significantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage calcification and vascular calcification. Function [...] (645 aa)
SLC4A3Anion exchange protein. (1226 aa)
MFSD12Major facilitator superfamily domain containing 12. (476 aa)
SLC16A1Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to [...] (501 aa)
SLC11A1Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] (570 aa)
SLCO2B1Solute carrier organic anion transporter family member. (707 aa)
TMCO3Transmembrane and coiled-coil domains 3. (677 aa)
SLC5A5Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (602 aa)
SLC6A3Sodium-dependent dopamine transporter; Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily. (750 aa)
CLCN7H(+)/Cl(-) exchange transporter 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen (By similarity). Belongs to the chloride channel (TC 2.A.49) family. ClC- 7/CLCN7 subfamily. (809 aa)
SLC10A2Solute carrier family 10 member 2. (336 aa)
SLC36A1Solute carrier family 36 member 1. (507 aa)
SLC12A6Solute carrier family 12 member 6. (1150 aa)
SLC25A14Solute carrier family 25 (Mitochondrial carrier, brain), member 14; Belongs to the mitochondrial carrier (TC 2.A.29) family. (325 aa)
SLC28A2Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (659 aa)
SLCO4C1Solute carrier organic anion transporter family member. (716 aa)
SLCO4A1Solute carrier organic anion transporter family member. (764 aa)
SLC25A30Solute carrier family 25 member 30; Belongs to the mitochondrial carrier (TC 2.A.29) family. (291 aa)
SLC35D3Solute carrier family 35 member D3. (423 aa)
SLC10A6Solute carrier family 10 member 6; Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (270 aa)
SLC8A1Sodium/calcium exchanger 1; Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage- gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels r [...] (970 aa)
SLC26A8Testis anion transporter 1; Acts as a DIDS-sensitive anion exchanger mediating chloride, sulfate and oxalate transport. May fulfill critical anion exchange functions in male germ line during meiosis and hence may play a role in spermatogenesis. May be involved in a new regulatory pathway linking sulfate transport to RhoGTPase signaling in male germ cells. A critical component of the sperm annulus that is essential for correct sperm tail differentiation and motility and hence male fertility (By similarity). Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (960 aa)
SLC4A8Anion exchange protein. (1092 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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