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CDH9-2 CDH9-2 CDH10 CDH10 CDH22 CDH22 AJUBA AJUBA ARVCF ARVCF CDH8 CDH8 CDH5 CDH5 SELL SELL CDH17 CDH17 CDH11 CDH11 NLGN1 NLGN1 CDH12 CDH12 CDH18 CDH18 CDH7 CDH7 SELP SELP DSC1 DSC1 CDH16 CDH16 PCDH12 PCDH12 E1BGM9_BOVIN E1BGM9_BOVIN CDH20 CDH20 CDH9 CDH9 DCHS1 DCHS1 CDH6 CDH6 CDH24 CDH24 CDH13 CDH13 CDH19 CDH19 ATP2C1 ATP2C1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDH9-2CDH9 protein. (81 aa)
CDH10Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
CDH22Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins. (869 aa)
AJUBALIM domain-containing protein ajuba; Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration. Contributes to the linking and/or strengthening of epithelia cell-cell junctions in part by linking adhesive receptors to the actin cytoskeleton. May be involved in signal transduction from cell adhesion sites to the nucleus. Plays an importa [...] (564 aa)
ARVCFARVCF delta catenin family member. (957 aa)
CDH8Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (799 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] (783 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (399 aa)
CDH17CDH17 protein. (832 aa)
CDH11Cadherin 11, type 2, OB-cadherin (Osteoblast); Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
NLGN1Neuroligin 1. (823 aa)
CDH12Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
CDH18Cadherin-18; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). (790 aa)
CDH7Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
SELPP-selectin; Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG (By similarity). Belongs to the selectin/LECAM family. (646 aa)
DSC1Desmocollin-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues. (893 aa)
CDH16Cadherin 16. (829 aa)
PCDH12Protocadherin 12. (1197 aa)
E1BGM9_BOVINUncharacterized protein. (291 aa)
CDH20Cadherin 20; Cadherins are calcium-dependent cell adhesion proteins. (801 aa)
CDH9Cadherin 9; Cadherins are calcium-dependent cell adhesion proteins. (658 aa)
DCHS1Dachsous cadherin-related 1. (3296 aa)
CDH6Cadherin-6; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). (790 aa)
CDH24Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins. (799 aa)
CDH13Cadherin-13; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth (By similarity). (701 aa)
CDH19CDH19 protein. (167 aa)
ATP2C1Calcium-transporting ATPase type 2C member 1; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (953 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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