STRINGSTRING
PATL1 PATL1 CNOT10 CNOT10 CNOT11 CNOT11 CPEB3 CPEB3 CNOT8 CNOT8 CNOT3 CNOT3 CNOT6 CNOT6 CNOT7 CNOT7 CNOT1 CNOT1 ZFP36 ZFP36 CNOT9 CNOT9 CNOT2 CNOT2 CNOT4 CNOT4 CNOT6L CNOT6L TNKS1BP1 TNKS1BP1 TOB1 TOB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PATL1PAT1 homolog 1, processing body mRNA decay factor. (806 aa)
CNOT10CCR4-NOT transcription complex subunit 10. (743 aa)
CNOT11CCR4-NOT transcription complex subunit 11. (511 aa)
CPEB3Cytoplasmic polyadenylation element binding protein 3. (697 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (292 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (744 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (557 aa)
CNOT7CCR4-NOT transcription complex subunit 7; Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translationa [...] (285 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2376 aa)
ZFP36mRNA decay activator protein ZFP36; Zinc-finger RNA-binding protein that destabilizes numerous cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as an 3'- untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1, and hence promotes ARE-mediated mRNA deadenylation. Functions also by recruiting compo [...] (325 aa)
CNOT9CCR4-NOT transcription complex subunit 9; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down- regulation of MYB- and JUN-dependent transcription. Enhances ligand- dependent transcriptional activity of nuclear hormone receptors. May play a role in cell d [...] (299 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (550 aa)
CNOT4CCR4-NOT transcription complex subunit 4. (713 aa)
CNOT6LEndo/exonuclease/phosphatase domain-containing protein. (555 aa)
TNKS1BP1Tankyrase 1 binding protein 1. (1774 aa)
TOB1Transducer of ERBB2, 1. (341 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.