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RAB26 | Ras-related protein Rab-26; Participates in exocrine secretion: regulates the secretion of acinar granules in the parotid gland; Belongs to the small GTPase superfamily. Rab family. (256 aa) | ||||
NKX3-1 | NK3 homeobox 1. (239 aa) | ||||
FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) | ||||
TWSG1 | Twisted gastrulation BMP signaling modulator 1. (223 aa) | ||||
PLXND1 | Plexin D1. (1783 aa) | ||||
LAMA5 | Laminin subunit alpha 5. (2649 aa) | ||||
IGSF3 | Immunoglobulin superfamily member 3. (1194 aa) | ||||
SEMA3C | Semaphorin-3C; Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity). (751 aa) | ||||
NFIB | Nuclear factor 1 B-type; Transcriptional activator of GFAP, essential for proper brain development. Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. (561 aa) | ||||
CELA1 | Chymotrypsin-like elastase family member 1; Acts upon elastin. (266 aa) | ||||
PDX1 | Pancreatic and duodenal homeobox 1. (285 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa) | ||||
CLCN2 | Chloride channel protein. (903 aa) | ||||
EDA | Ectodysplasin-A, membrane form; Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R. Isoform A1 binds only to the receptor EDAR, while isoform A2 binds exclusively to the receptor EDA2R. May also play a role in cell adhesion. Isoform A2 binds exclusively to the receptor EDA2R. (261 aa) | ||||
TGM2 | Protein-glutamine gamma-glutamyltransferase 2; Catalyzes the cross-linking of proteins, such as WDR54, and the conjugation of polyamines to proteins. Belongs to the transglutaminase superfamily. Transglutaminase family. (687 aa) | ||||
LAMA1 | Laminin subunit alpha 1. (3032 aa) | ||||
SRP54 | Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein); Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa) | ||||
EDAR | Ectodysplasin A receptor. (449 aa) | ||||
PLXNA1 | Plexin A1. (1929 aa) | ||||
SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa) | ||||
SOX10 | SRY-box transcription factor 10. (469 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (333 aa) | ||||
BMP7 | Bone morphogenetic protein 7. (431 aa) | ||||
TFCP2L1 | Transcription factor CP2 like 1. (490 aa) | ||||
POLB | DNA polymerase beta; Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases (By similarity). (380 aa) | ||||
FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) | ||||
PAX6 | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity); Belongs to the paired homeobox family. (436 aa) | ||||
TGFB2 | Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (442 aa) | ||||
TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (499 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa) | ||||
DAG1 | Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...] (1008 aa) | ||||
SOX9 | SRY-box transcription factor 9. (524 aa) |