STRINGSTRING
IFT140 IFT140 IFT122 IFT122 CILK1 CILK1 ENSBTAP00000066185 ENSBTAP00000066185 ENSBTAP00000063057 ENSBTAP00000063057 WDR60 WDR60 TCTEX1D2 TCTEX1D2 WDR35 WDR35 DYNLL1 DYNLL1 DYNC2LI1 DYNC2LI1 LOC784058 LOC784058 TTC21B TTC21B IFT43 IFT43 WDR19 WDR19 WDR34 WDR34 G3MX54_BOVIN G3MX54_BOVIN LOC101902172 LOC101902172 TTC21A TTC21A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFT140Intraflagellar transport 140. (1457 aa)
IFT122Intraflagellar transport 122. (1182 aa)
CILK1Intestinal cell kinase. (628 aa)
ENSBTAP00000066185Uncharacterized protein. (237 aa)
ENSBTAP00000063057Dynein light chain. (65 aa)
WDR60WD repeat domain 60. (1105 aa)
TCTEX1D2Tctex1 domain-containing protein 2; Required for proper retrograde ciliary transport. Belongs to the dynein light chain Tctex-type family. (294 aa)
WDR35WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking. (1238 aa)
DYNLL1Dynein light chain LC8-type 1. (89 aa)
DYNC2LI1Cytoplasmic dynein 2 light intermediate chain 1; Required for correct intraflagellar transport (IFT), the bi- directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Involved in the regulation of ciliary length. (377 aa)
LOC784058Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L [...] (89 aa)
TTC21BTetratricopeptide repeat domain 21B. (1316 aa)
IFT43Intraflagellar transport protein 43 homolog; As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs), it is involved in ciliogenesis. Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base. (207 aa)
WDR19WD repeat domain 19. (1342 aa)
WDR34WD repeat domain 34. (536 aa)
G3MX54_BOVINDynein light chain. (89 aa)
LOC101902172Dynein light chain. (63 aa)
TTC21ATetratricopeptide repeat domain 21A. (724 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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