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ABHD4 ABHD4 NAAA NAAA PLAAT5 PLAAT5 PLAAT1 PLAAT1 LOC618367 LOC618367 PLA2G4E PLA2G4E NAPEPLD NAPEPLD ENSBTAP00000070888 ENSBTAP00000070888 ENSBTAP00000071798 ENSBTAP00000071798 PLA2G16 PLA2G16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABHD4(Lyso)-N-acylphosphatidylethanolamine lipase; Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N- acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatid [...] (355 aa)
NAAAN-acylethanolamine acid amidase; Belongs to the acid ceramidase family. (357 aa)
PLAAT5HRASLS5 protein. (306 aa)
PLAAT1Phospholipase A and acyltransferase 1. (198 aa)
LOC618367LRAT domain-containing protein. (188 aa)
PLA2G4EPhospholipase A2. (836 aa)
NAPEPLDN-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of these bioactive fatty acid ethanolamides (FAEs), including anandamide (N-arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors (By similarity). As a regulator of lipid metabolism in the adipose tissue, mediates the crosstalk between adipocytes, gut microbiota and immune cells to control body temperature and weight. In particular, regulates energy homeostasis [...] (392 aa)
ENSBTAP00000070888LRAT domain-containing protein. (165 aa)
ENSBTAP00000071798LRAT domain-containing protein. (195 aa)
PLA2G16LRAT domain-containing protein. (161 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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