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| PLK4 | Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Phosphorylates 'Ser-151' of FBXW5 during the G1/S transition, leading to inhibit [...] (893 aa) | ||||
| CEP152 | Centrosomal protein 152. (1742 aa) | ||||
| DEUP1 | Deuterosome assembly protein 1. (436 aa) | ||||
| CEP63 | Centrosomal protein 63. (705 aa) | ||||