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A2ML1 | Alpha-2-macroglobulin like 1. (1396 aa) | ||||
OVOS2 | Uncharacterized protein. (1451 aa) | ||||
LOC506828 | Uncharacterized protein. (1462 aa) | ||||
A2M | Alpha-2-macroglobulin; Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the co [...] (478 aa) | ||||
C3 | Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates (By similarity). [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation. (1661 aa) | ||||
CD109 | CD109 molecule. (1455 aa) | ||||
CPAMD8 | C3 and PZP like alpha-2-macroglobulin domain containing 8. (1839 aa) | ||||
LOC107131209 | Uncharacterized protein. (1735 aa) | ||||
LOC528040 | Uncharacterized protein. (1699 aa) |