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| | EMX2 | Homeobox protein EMX2; Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system (By similarity). (253 aa) |
| | LHX5 | LIM homeobox 5. (402 aa) |
| | MEOX2 | Mesenchyme homeobox 2. (303 aa) |
| | HOXC4 | HOXC4 protein. (264 aa) |
| | VSX1 | Visual system homeobox 1; Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster (By similarity). May regulate the activity of the LCR and the cone opsin genes at earlier stages of development (By similarity). Dispensable in early retinal development (By similarity). (365 aa) |
| | LHX4 | LIM homeobox 4. (390 aa) |
| | SIX2 | SIX homeobox 2. (296 aa) |
| | HOXD13 | Homeobox D13. (341 aa) |
| | HOXD12 | Homeobox D12. (269 aa) |
| | BARX1 | BARX homeobox 1. (254 aa) |
| | PRRX1 | Paired related homeobox 1. (245 aa) |
| | PITX1 | Homeobox protein. (314 aa) |
| | MNX1 | Motor neuron and pancreas homeobox 1. (409 aa) |
| | HOXD3 | Homeobox D3. (434 aa) |
| | LHX6 | LIM homeobox 6. (392 aa) |
| | HOXB7 | Homeobox protein Hox-B7; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (217 aa) |
| | HOXC9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa) |
| | HOXB4 | Homeobox protein Hox-B4; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. Deformed subfamily. (251 aa) |
| | OTX2 | Orthodenticle homeobox 2. (289 aa) |
| | HOXA11 | Homeobox A11. (316 aa) |
| | HOXB13 | Homeobox B13. (285 aa) |
| | ZFHX3 | Zinc finger homeobox 3. (3704 aa) |
| | VSX2 | Visual system homeobox 2. (361 aa) |
| | HLX | H2.0-like homeobox protein; Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity); Belongs to the H2.0 homeobox family. (486 aa) |
| | HHEX | Hematopoietically expressed homeobox. (271 aa) |
| | BSX | Brain specific homeobox. (232 aa) |
| | MSX2 | Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter (By similarity). (267 aa) |
| | NKX2-8 | NK2 homeobox 8. (237 aa) |
| | SIX5 | SIX homeobox 5. (738 aa) |
| | PBX3 | PBX homeobox 3. (434 aa) |
| | HOXA5 | Homeobox protein Hox-A5; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3' (By similarity); Belongs to the Antp homeobox family. (381 aa) |
| | HOXC8 | Homeobox C8. (242 aa) |
| | SIX1 | SIX homeobox 1. (284 aa) |
| | CDX1 | CDX1 protein. (265 aa) |
| | DRGX | Dorsal root ganglia homeobox. (263 aa) |
| | NKX2-4 | NK2 homeobox 4. (347 aa) |
| | GBX1 | Gastrulation brain homeobox 1. (406 aa) |
| | TLX1 | Homeobox domain-containing protein. (335 aa) |
| | LHX2 | LIM homeobox 2. (406 aa) |
| | NKX3-2 | NK3 homeobox 2. (330 aa) |
| | MSX1 | Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa) |
| | PDX1 | Pancreatic and duodenal homeobox 1. (285 aa) |
| | VAX2 | Ventral anterior homeobox 2. (286 aa) |
| | GSC | Goosecoid homeobox. (257 aa) |
| | NKX2-2 | NK2 homeobox 2. (273 aa) |
| | TLX3 | Homeobox domain-containing protein. (291 aa) |
| | HOXB2 | Homeobox B2. (354 aa) |
| | PAX3 | Paired box 3. (484 aa) |
| | RAX2 | Retina and anterior neural fold homeobox protein 2; May be involved in modulating the expression of photoreceptor specific genes. Binds to the Ret-1 and Bat-1 element within the rhodopsin promoter (By similarity). (184 aa) |
| | HOXC5 | Homeobox C5. (222 aa) |
| | DMBX1 | Diencephalon/mesencephalon homeobox 1. (374 aa) |
| | OTP | Orthopedia homeobox. (325 aa) |
| | HOXC6 | Homeobox C6. (231 aa) |
| | PITX2 | Homeobox protein. (325 aa) |
| | GBX2 | Gastrulation brain homeobox 2. (349 aa) |
| | POU2F2 | POU domain protein. (467 aa) |
| | HOXA3 | Homeobox protein Hox-A3; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (442 aa) |
| | HOXA2 | Homeobox protein Hox-A2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. Proboscipedia subfamily. (372 aa) |
| | ISX | Intestine specific homeobox. (246 aa) |
| | HOXB1 | Homeobox B1. (302 aa) |
| | PROP1 | Homeobox protein prophet of Pit-1; Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes. (226 aa) |
| | DLX4 | Distal-less homeobox 4. (234 aa) |
| | ZFHX2 | Zinc finger homeobox 2. (2571 aa) |
| | HOXC11 | Homeobox C11. (304 aa) |
| | DBX2 | Homeobox protein DBX2. (340 aa) |
| | ESX1 | ESX homeobox 1. (279 aa) |
| | BARHL2 | BarH like homeobox 2. (380 aa) |
| | POU4F2 | POU domain protein. (407 aa) |
| | PAX7 | Paired box 7. (505 aa) |
| | ALX1 | ALX homeobox 1. (295 aa) |
| | DLX1 | Distal-less homeobox 1. (255 aa) |
| | PITX3 | Homeobox protein. (302 aa) |
| | POU3F4 | POU domain protein. (363 aa) |
| | HOXD1 | Homeobox D1. (322 aa) |
| | IRX4 | Iroquois homeobox 4. (522 aa) |
| | HOXD10 | HOXD10 protein. (340 aa) |
| | HOXD9 | Homeobox D9. (345 aa) |
| | IRX6 | Iroquois homeobox 6. (445 aa) |
| | ISL2 | ISL LIM homeobox 2. (359 aa) |
| | DLX3 | Distal-less homeobox 3. (287 aa) |
| | HMX2 | H6 family homeobox 2. (274 aa) |
| | DLX5 | Distal-less homeobox 5. (289 aa) |
| | POU4F3 | POU domain protein. (338 aa) |
| | PHOX2A | Paired like homeobox 2A. (284 aa) |
| | LHX8 | LIM homeobox 8. (377 aa) |
| | NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila). (323 aa) |
| | BARX2 | BARX homeobox 2. (278 aa) |
| | NANOG | Homeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator and repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT [...] (300 aa) |
| | NKX1-2 | NK1 homeobox 2. (301 aa) |
| | EVX1 | Even-skipped homeobox 1. (404 aa) |
| | ALX3 | ALX homeobox 3. (343 aa) |
| | POU5F1 | POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency (By similarity). Belongs to the POU transcription factor family. Class-5 subfamily. (360 aa) |
| | CRX | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity). (299 aa) |
| | POU2F3 | POU domain protein. (429 aa) |
| | NKX2-3 | NK2 transcription factor related, locus 3 (Drosophila). (367 aa) |
| | HOXB3 | HOXB3 protein. (426 aa) |
| | DLX6 | Distal-less homeobox 6. (175 aa) |
| | HOXD4 | HOXD4 protein. (258 aa) |
| | EN2 | Homeobox protein engrailed-like. (324 aa) |
| | CUX2 | Homeobox protein cut-like. (1502 aa) |
| | RAX | Retina and anterior neural fold homeobox. (352 aa) |
| | BARHL1 | BarH like homeobox 1. (327 aa) |
| | VAX1 | Ventral anterior homeobox 1. (334 aa) |
| | LBX1 | Ladybird homeobox 1. (282 aa) |
| | HOXA6 | Homeobox A6. (233 aa) |
| | POU3F2 | POU domain protein. (438 aa) |
| | SHOX | Short stature homeobox. (306 aa) |
| | EN1 | Homeobox protein engrailed-like. (400 aa) |
| | POU4F1 | POU domain protein. (421 aa) |
| | HOXA9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa) |
| | LMX1A | LIM homeobox transcription factor 1 alpha. (382 aa) |
| | HESX1 | HESX homeobox 1. (201 aa) |
| | HOXB8 | Homeobox B8. (243 aa) |
| | OTX1 | Orthodenticle homeobox 1. (355 aa) |
| | HOXB6 | Homeobox B6. (224 aa) |
| | CUX1 | Homeobox protein cut-like. (1648 aa) |
| | NKX2-1 | NK2 homeobox 1. (408 aa) |
| | NKX6-2 | NK6 homeobox 2. (278 aa) |
| | HOXD8 | Homeobox D8. (277 aa) |
| | SIX4 | SIX homeobox 4. (786 aa) |
| | LMX1B | LIM homeobox transcription factor 1 beta. (395 aa) |
| | POU2F1 | POU domain protein. (768 aa) |
| | HOXC10 | Homeobox C10. (373 aa) |
| | NKX1-1 | NK1 homeobox 1. (399 aa) |
| | IRX5 | Iroquois homeobox 5. (500 aa) |
| | PAX6 | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity); Belongs to the paired homeobox family. (436 aa) |
| | HOXA7 | Homeobox A7. (238 aa) |
| | PBX1 | PBX homeobox 1. (325 aa) |
| | PAX4 | Paired box 4. (368 aa) |
| | IRX3 | Iroquois homeobox 3. (502 aa) |
| | MKX | Mohawk homeobox. (352 aa) |
| | HOXB9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa) |
| | POU3F3 | POU domain protein. (499 aa) |
| | EVX2 | Even-skipped homeobox 2. (474 aa) |
| | GSX2 | GS homeobox 2. (305 aa) |
| | IRX2 | Iroquois homeobox 2. (476 aa) |
| | G3N017_BOVIN | Homeobox domain-containing protein. (234 aa) |
| | GSC2 | Goosecoid homeobox 2. (213 aa) |
| | HOXB5 | Homeobox B5. (269 aa) |
| | POU3F1 | POU domain protein. (451 aa) |
| | HOXA4 | Homeobox A4. (319 aa) |
| | G3MWG9_BOVIN | Homeobox domain-containing protein. (262 aa) |
| | PBX2 | PBX homeobox 2. (347 aa) |
| | ZFHX4 | Zinc finger homeobox 4. (3622 aa) |
| | PHOX2B | Paired like homeobox 2B. (315 aa) |
| | HOXD11 | Homeobox D11. (337 aa) |
| | LHX3 | LIM homeodomain 3 protein b isoform. (403 aa) |
| | HOXA10 | HOXA10 protein. (94 aa) |
| | NKX2-6 | NK2 homeobox 6. (300 aa) |
| | HMX1 | H6 family homeobox 1. (347 aa) |
| | POU1F1 | Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'. (291 aa) |
| | MEOX1 | Mesenchyme homeobox 1. (254 aa) |
| | LHX1 | LIM homeobox 1. (406 aa) |
| | CDX2 | Homeobox domain-containing protein. (306 aa) |
| | NKX6-3 | NK6 homeobox 3. (263 aa) |
| | ALX4 | Homeobox protein aristaless-like 4; Transcription factor involved in skull and limb development. (397 aa) |
| | MIXL1 | Mix paired-like homeobox. (237 aa) |
| | DLX2 | Distal-less homeobox 2. (331 aa) |
| | HOXA13 | Homeobox A13. (388 aa) |
| | HMX3 | H6 family homeobox 3. (359 aa) |
| | SHOX2 | Short stature homeobox 2. (353 aa) |
| | LHX9 | LIM/homeobox protein Lhx9; Involved in gonadal development. (378 aa) |
| | IRX1 | Iroquois homeobox 1. (476 aa) |
| | HOXC13 | HOXC13 protein. (330 aa) |
| | HOXC12 | Homeobox C12. (281 aa) |
| | HOXA1 | Homeobox A1. (333 aa) |
| | NKX3-1 | NK3 homeobox 1. (239 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | CDX4 | Caudal type homeobox 4. (274 aa) |
| | EMX1 | Empty spiracles homeobox 1. (288 aa) |
| | NKX6-1 | NK6 homeobox 1. (366 aa) |
| | DBX1 | Homeobox protein DBX1; Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity); Belongs to the H2.0 homeobox family. (345 aa) |
| | PRRX2 | Paired related homeobox 2. (254 aa) |
