STRINGSTRING
CSTA CSTA CSTB CSTB CSTB-2 CSTB-2 KNG1 KNG1 CST6 CST6 CST3 CST3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSTACystatin-A; This is an intracellular thiol proteinase inhibitor; Belongs to the cystatin family. (98 aa)
CSTBCystatin-B; This is an intracellular thiol proteinase inhibitor. (149 aa)
CSTB-2Stefin-C; Strong inhibitor of papain and cathepsin L but poor inhibitor of cathepsin B; Belongs to the cystatin family. (101 aa)
KNG1Kininogen-1 heavy chain; (1) Kininogens are inhibitors of thiol proteases; (2) HMW- kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of [...] (621 aa)
CST6Cystatin E/M; Belongs to the cystatin family. (149 aa)
CST3Cystatin-C; This is a thiol proteinase inhibitor. (219 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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