| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IRF1 | IRF4 | ENSBTAP00000041732 | ENSBTAP00000003812 | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | Interferon regulatory factor 4. | 0.512 |
| IRF1 | IRF5 | ENSBTAP00000041732 | ENSBTAP00000006567 | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | Interferon regulatory factor 5; Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling (By similarity). | 0.461 |
| IRF1 | IRF6 | ENSBTAP00000041732 | ENSBTAP00000003694 | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | Interferon regulatory factor 6; Probable DNA-binding transcriptional activator. It is a key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development. Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity); Belongs to the IRF family. | 0.405 |
| IRF1 | IRF7 | ENSBTAP00000041732 | ENSBTAP00000059765 | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | Interferon regulatory factor 7. | 0.658 |
| IRF1 | IRF8 | ENSBTAP00000041732 | ENSBTAP00000023694 | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | Interferon regulatory factor 8. | 0.794 |
| IRF1 | IRF9 | ENSBTAP00000041732 | ENSBTAP00000036313 | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | Interferon-stimulated transcription factor 3, gamma 48kDa. | 0.667 |
| IRF1 | LOC618409 | ENSBTAP00000041732 | ENSBTAP00000065246 | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | IRF tryptophan pentad repeat domain-containing protein. | 0.413 |
| IRF4 | IRF1 | ENSBTAP00000003812 | ENSBTAP00000041732 | Interferon regulatory factor 4. | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | 0.512 |
| IRF4 | IRF7 | ENSBTAP00000003812 | ENSBTAP00000059765 | Interferon regulatory factor 4. | Interferon regulatory factor 7. | 0.530 |
| IRF4 | IRF8 | ENSBTAP00000003812 | ENSBTAP00000023694 | Interferon regulatory factor 4. | Interferon regulatory factor 8. | 0.482 |
| IRF4 | LOC618409 | ENSBTAP00000003812 | ENSBTAP00000065246 | Interferon regulatory factor 4. | IRF tryptophan pentad repeat domain-containing protein. | 0.900 |
| IRF5 | IRF1 | ENSBTAP00000006567 | ENSBTAP00000041732 | Interferon regulatory factor 5; Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling (By similarity). | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | 0.461 |
| IRF5 | IRF8 | ENSBTAP00000006567 | ENSBTAP00000023694 | Interferon regulatory factor 5; Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling (By similarity). | Interferon regulatory factor 8. | 0.422 |
| IRF6 | IRF1 | ENSBTAP00000003694 | ENSBTAP00000041732 | Interferon regulatory factor 6; Probable DNA-binding transcriptional activator. It is a key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development. Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity); Belongs to the IRF family. | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | 0.405 |
| IRF7 | IRF1 | ENSBTAP00000059765 | ENSBTAP00000041732 | Interferon regulatory factor 7. | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | 0.658 |
| IRF7 | IRF4 | ENSBTAP00000059765 | ENSBTAP00000003812 | Interferon regulatory factor 7. | Interferon regulatory factor 4. | 0.530 |
| IRF7 | IRF9 | ENSBTAP00000059765 | ENSBTAP00000036313 | Interferon regulatory factor 7. | Interferon-stimulated transcription factor 3, gamma 48kDa. | 0.707 |
| IRF7 | LOC618409 | ENSBTAP00000059765 | ENSBTAP00000065246 | Interferon regulatory factor 7. | IRF tryptophan pentad repeat domain-containing protein. | 0.434 |
| IRF8 | IRF1 | ENSBTAP00000023694 | ENSBTAP00000041732 | Interferon regulatory factor 8. | Interferon regulatory factor 1; Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target [...] | 0.794 |
| IRF8 | IRF4 | ENSBTAP00000023694 | ENSBTAP00000003812 | Interferon regulatory factor 8. | Interferon regulatory factor 4. | 0.482 |