STRINGSTRING
EPRS1 EPRS1 GSTP1 GSTP1 GSTM3 GSTM3 GSTP1-2 GSTP1-2 MTX1 MTX1 GSTM1-2 GSTM1-2 GSTA4 GSTA4 GSTA1 GSTA1 GSTZ1 GSTZ1 ENSBTAP00000073566 ENSBTAP00000073566 GDAP1L1 GDAP1L1 EEF1E1 EEF1E1 GSTO2 GSTO2 GSTO1 GSTO1 GSTT1 GSTT1 VARS1 VARS1 MTX2 MTX2 AIMP2 AIMP2 CARS1 CARS1 CLIC2 CLIC2 EEF1G EEF1G GDAP1 GDAP1 LOC100295687 LOC100295687 LOC785216 LOC785216 GSTA3 GSTA3 MTX3 MTX3 CLIC1 CLIC1 GSTCD GSTCD CLIC3 CLIC3 GSTM1 GSTM1 HPGDS HPGDS GSTA5 GSTA5 E1BKD8_BOVIN E1BKD8_BOVIN GSTT2 GSTT2 GSTA2 GSTA2 CLIC4 CLIC4 FAXC FAXC G3N3V2_BOVIN G3N3V2_BOVIN PTGES2 PTGES2 CLIC5 CLIC5 MARS1 MARS1 GSTT4 GSTT4 CLIC6 CLIC6 EEF1B2 EEF1B2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPRS1Glutamyl-prolyl-tRNA synthetase. (1518 aa)
GSTP1Glutathione S-transferase P; Belongs to the GST superfamily. (191 aa)
GSTM3Glutathione S-transferase. (240 aa)
GSTP1-2Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity); Belongs to the GST superfamily. Pi family. (240 aa)
MTX1Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. (465 aa)
GSTM1-2Uncharacterized protein. (266 aa)
GSTA4Glutathione S-transferase A4; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Alpha family. (303 aa)
GSTA1Glutathione S-transferase. (291 aa)
GSTZ1Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (445 aa)
ENSBTAP00000073566Uncharacterized protein. (244 aa)
GDAP1L1Ganglioside-induced differentiation-associated protein 1-like 1. (367 aa)
EEF1E1Eukaryotic translation elongation factor 1 epsilon 1. (174 aa)
GSTO2Glutathione S-transferase omega 2; Belongs to the GST superfamily. (244 aa)
GSTO1Uncharacterized protein; Belongs to the GST superfamily. (241 aa)
GSTT1Glutathione S-transferase theta-1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity; Belongs to the GST superfamily. Theta family. (240 aa)
VARS1Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1264 aa)
MTX2MTX2 protein. (264 aa)
AIMP2Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2- mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. (320 aa)
CARS1Cysteinyl-tRNA synthetase. (832 aa)
CLIC2Chloride intracellular channel 2. (247 aa)
EEF1GElongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components. (440 aa)
GDAP1Ganglioside-induced differentiation-associated protein 1; Regulates the mitochondrial network by promoting mitochondrial fission; Belongs to the GST superfamily. (358 aa)
LOC100295687Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Protects against the thiol-mediated metal-catalysed oxidative inactivation of enzymes. Belongs to the GST superfamily. Mu family. (218 aa)
LOC785216Uncharacterized protein. (344 aa)
GSTA3Glutathione S-transferase, alpha 3. (222 aa)
MTX3Metaxin. (312 aa)
CLIC1Chloride intracellular channel protein 1; Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions (By similarity). (241 aa)
GSTCDGlutathione S-transferase C-terminal domain-containing protein. (631 aa)
CLIC3Chloride intracellular channel 3. (237 aa)
GSTM1Glutathione S-transferase Mu 1; Belongs to the GST superfamily. (218 aa)
HPGDSHematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa)
GSTA5Glutathione S-transferase. (222 aa)
E1BKD8_BOVINUncharacterized protein. (224 aa)
GSTT2Uncharacterized protein; Belongs to the GST superfamily. (281 aa)
GSTA2Glutathione S-transferase A2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. (223 aa)
CLIC4Chloride intracellular channel protein 4; Can insert into membranes and form chloride ion channels. (253 aa)
FAXCFailed axon connections homolog, metaxin like GST domain containing. (409 aa)
G3N3V2_BOVINChloride intracellular channel protein; Belongs to the chloride channel CLIC family. (137 aa)
PTGES2Prostaglandin E synthase 2 truncated form; Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2); Belongs to the GST superfamily. (431 aa)
CLIC5Chloride intracellular channel protein 5; Required for normal hearing. It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti. Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion. Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture. Plays a role in formation of the lens suture in the eye, which is important for normal optical propert [...] (467 aa)
MARS1Methionine--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus; Belongs to the class-I aminoacyl-tRNA synthetase family. (906 aa)
GSTT4Uncharacterized protein; Belongs to the GST superfamily. (241 aa)
CLIC6Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (655 aa)
EEF1B2Elongation factor 1-beta; EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. (225 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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