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PDE4C PDE4C PDE4B PDE4B PDE3B PDE3B PDE1B PDE1B PDE6C PDE6C PDE4D PDE4D PDE1C PDE1C PDE8B PDE8B PDE9A PDE9A PDE8A PDE8A PDE3A PDE3A PDE2A PDE2A PDE10A PDE10A PDE6B PDE6B PDE1A PDE1A PDE7B PDE7B PDE6A PDE6A PDE11A PDE11A PDE4A PDE4A PDE7A PDE7A PDE5A PDE5A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDE4CPhosphodiesterase. (694 aa)
PDE4BPhosphodiesterase. (721 aa)
PDE3BPhosphodiesterase. (1115 aa)
PDE1BCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate (By similarity). (535 aa)
PDE6CCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP. (855 aa)
PDE4DPhosphodiesterase. (678 aa)
PDE1CPhosphodiesterase. (670 aa)
PDE8BPhosphodiesterase. (873 aa)
PDE9APhosphodiesterase. (563 aa)
PDE8APhosphodiesterase. (867 aa)
PDE3APhosphodiesterase. (866 aa)
PDE2AcGMP-dependent 3',5'-cyclic phosphodiesterase; Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. (1015 aa)
PDE10APhosphodiesterase. (763 aa)
PDE6BRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta; This protein participates in processes of transmission and amplification of the visual signal. Necessary for the formation of a functional phosphodiesterase holoenzyme. (867 aa)
PDE1ACalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP (By similarity). (530 aa)
PDE7BPhosphodiesterase. (501 aa)
PDE6ARod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; This protein participates in processes of transmission and amplification of the visual signal. (859 aa)
PDE11APhosphodiesterase. (926 aa)
PDE4APhosphodiesterase. (872 aa)
PDE7APhosphodiesterase 7A; Belongs to the cyclic nucleotide phosphodiesterase family. (251 aa)
PDE5AcGMP-specific 3',5'-cyclic phosphodiesterase; Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. Specifically regulates nitric-oxide-generated cGMP (By similarity). (865 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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