STRINGSTRING
CCNJ CCNJ CCNJL CCNJL ENSBTAP00000059482 ENSBTAP00000059482 ENSBTAP00000058474 ENSBTAP00000058474 CNTD2 CNTD2 CCNI2 CCNI2 CCNO CCNO CCNA1 CCNA1 CCNG1 CCNG1 CCNB2 CCNB2 CCNA2 CCNA2 CCNE2 CCNE2 CCNE1 CCNE1 CCNI CCNI CCNF CCNF CCNG2 CCNG2 CCND3 CCND3 CCNB3 CCNB3 CCNB1 CCNB1 CCND1 CCND1 CCND2 CCND2 ENSBTAP00000072302 ENSBTAP00000072302
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNJCyclin J; Belongs to the cyclin family. (383 aa)
CCNJLCyclin J like; Belongs to the cyclin family. (386 aa)
ENSBTAP00000059482Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (375 aa)
ENSBTAP00000058474CYCLIN domain-containing protein; Belongs to the cyclin family. (283 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (293 aa)
CCNI2Cyclin I family member 2; Belongs to the cyclin family. (361 aa)
CCNOCyclin O; Belongs to the cyclin family. (351 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (490 aa)
CCNG1Cyclin-G1; May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity); Belongs to the cyclin family. Cyclin G subfamily. (295 aa)
CCNB2G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition. (398 aa)
CCNA2Cyclin-A2; Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle. (429 aa)
CCNE2G1/S-specific cyclin-E2; Essential for the control of the cell cycle at the late G1 and early S phase; Belongs to the cyclin family. Cyclin E subfamily. (404 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (411 aa)
CCNICCNI protein; Belongs to the cyclin family. (377 aa)
CCNFCyclin-F; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. Belongs to the cyclin family. Cyclin AB subfamily. (1215 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (344 aa)
CCND3G1/S-specific cyclin-D3; Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...] (292 aa)
CCNB3Cyclin B3; Belongs to the cyclin family. (1208 aa)
CCNB1G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily. (427 aa)
CCND1G1/S-specific cyclin-D1; Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...] (428 aa)
CCND2G1/S-specific cyclin-D2; Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...] (289 aa)
ENSBTAP00000072302CYCLIN domain-containing protein; Belongs to the cyclin family. (257 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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