(17 nodes) (2006) Ontogeny of mRNA abundance of nuclear receptors and nuclear receptor target genes in young cattle. network (Bos taurus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Your Input:
	LOC615303	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
	CYP3A4	Uncharacterized protein. (503 aa)
	NR1I3	Nuclear receptor subfamily 1 group I member 3. (406 aa)
	CYP3A5	Cytochrome P450 3A28; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (507 aa)
	UGT2B10	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
	NR1I2	Nuclear receptor subfamily 1 group I member 2. (420 aa)
	LOC100138004	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (531 aa)
	LOC781988	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
	UGT1A1	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (533 aa)
	MGC152010	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
	UGT2A1	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
	ENSBTAP00000060742	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (486 aa)
	LOC100296421	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
	LOC100138908	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (532 aa)
	LOC530553	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
	LOC540544	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (533 aa)
	ENSBTAP00000071522	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (494 aa)

Your Current Organism:

Bos taurus

NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP3A4	CYP3A5	ENSBTAP00000007170	ENSBTAP00000016177	Uncharacterized protein.	Cytochrome P450 3A28; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.407
CYP3A4	ENSBTAP00000060742	ENSBTAP00000007170	ENSBTAP00000060742	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.723
CYP3A4	ENSBTAP00000071522	ENSBTAP00000007170	ENSBTAP00000071522	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.718
CYP3A4	LOC100138004	ENSBTAP00000007170	ENSBTAP00000029956	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.904
CYP3A4	LOC100138908	ENSBTAP00000007170	ENSBTAP00000062781	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.904
CYP3A4	LOC100296421	ENSBTAP00000007170	ENSBTAP00000061729	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.904
CYP3A4	LOC530553	ENSBTAP00000007170	ENSBTAP00000069492	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.903
CYP3A4	LOC540544	ENSBTAP00000007170	ENSBTAP00000071154	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.901
CYP3A4	LOC615303	ENSBTAP00000007170	ENSBTAP00000004581	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.904
CYP3A4	LOC781988	ENSBTAP00000007170	ENSBTAP00000029965	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.906
CYP3A4	MGC152010	ENSBTAP00000007170	ENSBTAP00000050702	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.903
CYP3A4	NR1I2	ENSBTAP00000007170	ENSBTAP00000026059	Uncharacterized protein.	Nuclear receptor subfamily 1 group I member 2.	0.877
CYP3A4	NR1I3	ENSBTAP00000007170	ENSBTAP00000012145	Uncharacterized protein.	Nuclear receptor subfamily 1 group I member 3.	0.795
CYP3A4	UGT1A1	ENSBTAP00000007170	ENSBTAP00000036928	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.933
CYP3A4	UGT2A1	ENSBTAP00000007170	ENSBTAP00000051040	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.904
CYP3A4	UGT2B10	ENSBTAP00000007170	ENSBTAP00000022664	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.922
CYP3A5	CYP3A4	ENSBTAP00000016177	ENSBTAP00000007170	Cytochrome P450 3A28; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Uncharacterized protein.	0.407
CYP3A5	ENSBTAP00000060742	ENSBTAP00000016177	ENSBTAP00000060742	Cytochrome P450 3A28; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.738
CYP3A5	ENSBTAP00000071522	ENSBTAP00000016177	ENSBTAP00000071522	Cytochrome P450 3A28; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.734
CYP3A5	LOC100138004	ENSBTAP00000016177	ENSBTAP00000029956	Cytochrome P450 3A28; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.904

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